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Contribution of Topoisomerase IV Mutation to Quinolone Resistance in Mycoplasma genitalium

Antimicrobial Agents and Chemotherapy, 2013-04, Vol.57 (4), p.1772-1776

2013

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Structures of Kibdelomycin Bound to Staphylococcus aureus GyrB and ParE Showed a Novel U‑Shaped Binding Mode

ACS chemical biology, 2014-09, Vol.9 (9), p.2023-2031

2014

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Relationship between the expression of ompF and quinolone resistance in Escherichia coli

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2009-12, Vol.15 (6), p.361-366

2009

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Kibdelomycin is a bactericidal broad-spectrum aerobic antibacterial agent

Antimicrobial agents and chemotherapy, 2015-06, Vol.59 (6), p.3474-3481

2015

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Synthesis and Antibacterial Activity of Novel Pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic Acid Derivatives Carrying the 3-Cyclopropylaminomethyl-4-substituted-1-pyrrolidinyl Group as a C-10 Substituent

Journal of medicinal chemistry, 2008-06, Vol.51 (11), p.3238-3249

2008

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PA subunit of RNA polymerase as a promising target for anti-influenza virus agents

Antiviral research, 2008-06, Vol.78 (3), p.194-201

2008

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Target Preference of 15 Quinolones against Staphylococcus aureus, Based on Antibacterial Activities and Target Inhibition

Antimicrobial Agents and Chemotherapy, 2001-12, Vol.45 (12), p.3544-3547

2001

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In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP-AM1977)

Antimicrobial agents and chemotherapy, 2017-06, Vol.61 (6)

2017

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Dietary Yeasts Reduce Inflammation in Central Nerve System via Microflora

Annals of clinical and translational neurology, 2015-01, Vol.2 (1), p.56-66

2015

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Hybrid Control for Machine Tool Table Applying Sensorless Cutting Force Monitoring

International journal of automation technology, 2011-07, Vol.5 (4), p.587-593

2011

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Contributions of the 8-Methoxy Group of Gatifloxacin to Resistance Selectivity, Target Preference, and Antibacterial Activity against Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy, 2001-06, Vol.45 (6), p.1649-1653

2001

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Real-Time Cutting Force/Torque Prediction During Turning

International journal of automation technology, 2012-09, Vol.6 (5), p.669-674

2012

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Cultivation of Neisseria gonorrhoeae in Liquid Media and Determination of Its In Vitro Susceptibilities to Quinolones

Journal of Clinical Microbiology, 2005-09, Vol.43 (9), p.4321-4327

2005

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Contribution of the 8-Methoxy Group to the Activity of Gatifloxacin against Type II Topoisomerases of Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy, 2003-01, Vol.47 (1), p.77-81

2003

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Reply to comment on: Dietary yeasts reduce inflammation in central nervous system via microflora

Annals of clinical and translational neurology, 2015-11, Vol.2 (11), p.1040-1040

2015

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Efficacy of Quinolones against Secondary Pneumococcal Pneumonia after Influenza Virus Infection in Mice

Antimicrobial Agents and Chemotherapy, 2006-02, Vol.50 (2), p.748-751

2006

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Structure activity relationship of N-1 substituted 1,5-naphthyrid-2-one analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-9)

Bioorganic & medicinal chemistry letters, 2022-11, Vol.75, p.128808, Article 128808

2022

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Inhibitory Activities of Gatifloxacin (AM-1155), a Newly Developed Fluoroquinolone, against Bacterial and Mammalian Type II Topoisomerases

Antimicrobial Agents and Chemotherapy, 1998-10, Vol.42 (10), p.2678-2681

1998

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The effect of pharmacokinetic/pharmacodynamic (PK/PD) parameters of gatifloxacin on its bactericidal activity and resistance selectivity against clinical isolates of Streptococcus pneumoniae

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2003-09, Vol.9 (3), p.210-214

2003

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In Vitro and In Vivo Characterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4830-4839

2016

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Oxabicyclooctane-Linked Novel Bacterial Topoisomerase Inhibitors as Broad Spectrum Antibacterial Agents

ACS medicinal chemistry letters, 2014-05, Vol.5 (5), p.609-614

2014

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Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2)

Bioorganic & medicinal chemistry letters, 2015-05, Vol.25 (9), p.1831-1835

2015

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Hydroxy tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of RHS moiety (Part-3)

Bioorganic & medicinal chemistry letters, 2015-06, Vol.25 (12), p.2473-2478

2015

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Structure activity relationship of C-2 ether substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-5)

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3630-3635

2015

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Structure activity relationship of pyridoxazinone substituted RHS analogs of oxabicyclooctane-linked 1,5-naphthyridinyl novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-6)

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3636-3643

2015

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Contribution of Topoisomerase IV Mutation to Quinolone Resistance in Mycoplasma genitalium

Structures of Kibdelomycin Bound to Staphylococcus aureus GyrB and ParE Showed a Novel U‑Shaped Binding Mode

Relationship between the expression of ompF and quinolone resistance in Escherichia coli

Kibdelomycin is a bactericidal broad-spectrum aerobic antibacterial agent

Synthesis and Antibacterial Activity of Novel Pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic Acid Derivatives Carrying the 3-Cyclopropylaminomethyl-4-substituted-1-pyrrolidinyl Group as a C-10 Substituent

PA subunit of RNA polymerase as a promising target for anti-influenza virus agents

Target Preference of 15 Quinolones against Staphylococcus aureus, Based on Antibacterial Activities and Target Inhibition

In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP-AM1977)

Dietary Yeasts Reduce Inflammation in Central Nerve System via Microflora

Hybrid Control for Machine Tool Table Applying Sensorless Cutting Force Monitoring

Contributions of the 8-Methoxy Group of Gatifloxacin to Resistance Selectivity, Target Preference, and Antibacterial Activity against Streptococcus pneumoniae

Real-Time Cutting Force/Torque Prediction During Turning

Cultivation of Neisseria gonorrhoeae in Liquid Media and Determination of Its In Vitro Susceptibilities to Quinolones

Contribution of the 8-Methoxy Group to the Activity of Gatifloxacin against Type II Topoisomerases of Streptococcus pneumoniae

Reply to comment on: Dietary yeasts reduce inflammation in central nervous system via microflora

Efficacy of Quinolones against Secondary Pneumococcal Pneumonia after Influenza Virus Infection in Mice

Structure activity relationship of N-1 substituted 1,5-naphthyrid-2-one analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-9)

Inhibitory Activities of Gatifloxacin (AM-1155), a Newly Developed Fluoroquinolone, against Bacterial and Mammalian Type II Topoisomerases

The effect of pharmacokinetic/pharmacodynamic (PK/PD) parameters of gatifloxacin on its bactericidal activity and resistance selectivity against clinical isolates of Streptococcus pneumoniae

In Vitro and In Vivo Characterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase

Oxabicyclooctane-Linked Novel Bacterial Topoisomerase Inhibitors as Broad Spectrum Antibacterial Agents

Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2)

Hydroxy tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of RHS moiety (Part-3)

Structure activity relationship of C-2 ether substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-5)

Structure activity relationship of pyridoxazinone substituted RHS analogs of oxabicyclooctane-linked 1,5-naphthyridinyl novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-6)

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