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Partial recovery of visual function in a blind patient after optogenetic therapy

Nature Medicine, 2021-07, Vol.27 (7), p.1223-1229

2021

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Long-Term Follow-Up After Unilateral Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy: The RESTORE Study

Journal of neuro-ophthalmology, 2021-09, Vol.41 (3), p.309-315

2021

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Biodistribution of intravitreal lenadogene nolparvovec gene therapy in nonhuman primates

Molecular therapy. Methods & clinical development, 2021-12, Vol.23, p.307-318

2021

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Absence of lenadogene nolparvovec DNA in a brain tumor biopsy from a patient in the REVERSE clinical study, a case report

BMC neurology, 2022-07, Vol.22 (1), p.257-7, Article 257

2022

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Visual Outcomes in Leber Hereditary Optic Neuropathy Patients With the m.11778G>A (MTND4) Mitochondrial DNA Mutation

Journal of neuro-ophthalmology, 2020-12, Vol.40 (4), p.547-557

2020

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Prasugrel Use in Real Life: A Report From the Outpatient Setting in France

Clinical cardiology (Mahwah, N.J.), 2016-07, Vol.39 (7), p.378-384

2016

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Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy

Science translational medicine, 2020-12, Vol.12 (573)

2020

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The Impact of Leber Hereditary Optic Neuropathy on the Quality of Life of Patients and Their Relatives: A Qualitative Study

Journal of neuro-ophthalmology, 2022-09, Vol.42 (3), p.316-322

2022

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Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated within 6 Months of Disease Onset

Ophthalmology (Rochester, Minn.), 2021-05, Vol.128 (5), p.649-660

2021

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Ocular stress enhances contralateral transfer of lenadogene nolparvovec gene therapy through astrocyte networks

Molecular therapy, 2023-07, Vol.31 (7), p.2005-2013

2023

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Randomized trial of bilateral gene therapy injection for m.11778G>A MT-ND4 Leber optic neuropathy

Brain (London, England : 1878), 2023-04, Vol.146 (4), p.1328-1341

2023

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Natural history of patients with Leber hereditary optic neuropathy-results from the REALITY study

Eye (London), 2022-04, Vol.36 (4), p.818-826

2022

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Safety of Intravitreal Gene Therapy for Treatment of Subjects with Leber Hereditary Optic Neuropathy due to Mutations in the Mitochondrial ND4 Gene: The REVEAL Study

BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2021-03, Vol.35 (2), p.201-214

2021

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Safety of Lenadogene Nolparvovec Gene Therapy Over 5 Years in 189 Patients With Leber Hereditary Optic Neuropathy

American journal of ophthalmology, 2023-05, Vol.249, p.108-125

2023

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The phase 3 REFLECT trial: Efficacy and safety of bilateral gene therapy for Leber hereditary optic neuropathy (LHON)

Acta ophthalmologica (Oxford, England), 2022-12, Vol.100 (S275), p.n/a

2022

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Leber hereditary optic neuropathy: Bilateral improvement of visual acuity following gene therapy by unilateral injection

M.S. Médecine sciences, 2021-08, Vol.37 (8-9), p.712

2021

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Gene Therapies for the Treatment of Leber Hereditary Optic Neuropathy

International ophthalmology clinics, 2021, Vol.61 (4), p.195

2021

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Cross-Sectional Analysis of Baseline Visual Parameters in Subjects Recruited Into the RESCUE and REVERSE ND4-LHON Gene Therapy Studies

Journal of neuro-ophthalmology, 2021-09, Vol.41 (3), p.298-308

2021

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New antiplatelet agents in the treatment of acute coronary syndromes

Archives of cardiovascular diseases, 2014-03, Vol.107 (3), p.178-187

2014

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Study design and baseline characteristics for the reflect gene therapy trial ofm.11778g>A/ND4-LHON

BMJ open ophthalmology, 2022-11, Vol.7 (1), p.e001158

2022

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Absence of lenadogene nolparvovec DNA in a brain tumor biopsy from a patient in the REVERSE clinical study, a case report

BMC neurology, 2022, Vol.22 (1), p.257-257

2022

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Diagnostic value of fundus examination in familial adenomatous polyposis

British journal of ophthalmology, 1997-09, Vol.81 (9), p.755-758

1997

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Partial recovery of visual function in a blind patient after optogenetic therapy

Long-Term Follow-Up After Unilateral Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy: The RESTORE Study

Intravitreal Gene Therapy vs. Natural History in Patients With Leber Hereditary Optic Neuropathy Carrying the m.11778G>A ND4 Mutation: Systematic Review and Indirect Comparison

Biodistribution of intravitreal lenadogene nolparvovec gene therapy in nonhuman primates

Absence of lenadogene nolparvovec DNA in a brain tumor biopsy from a patient in the REVERSE clinical study, a case report

Visual Outcomes in Leber Hereditary Optic Neuropathy Patients With the m.11778G>A (MTND4) Mitochondrial DNA Mutation

Prasugrel Use in Real Life: A Report From the Outpatient Setting in France

Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy

The Impact of Leber Hereditary Optic Neuropathy on the Quality of Life of Patients and Their Relatives: A Qualitative Study

Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated within 6 Months of Disease Onset

Effect of an intravitreal antisense oligonucleotide on vision in Leber congenital amaurosis due to a photoreceptor cilium defect

Ocular stress enhances contralateral transfer of lenadogene nolparvovec gene therapy through astrocyte networks

Randomized trial of bilateral gene therapy injection for m.11778G>A MT-ND4 Leber optic neuropathy

Natural history of patients with Leber hereditary optic neuropathy-results from the REALITY study

Safety of Intravitreal Gene Therapy for Treatment of Subjects with Leber Hereditary Optic Neuropathy due to Mutations in the Mitochondrial ND4 Gene: The REVEAL Study

Safety of Lenadogene Nolparvovec Gene Therapy Over 5 Years in 189 Patients With Leber Hereditary Optic Neuropathy

The phase 3 REFLECT trial: Efficacy and safety of bilateral gene therapy for Leber hereditary optic neuropathy (LHON)

Leber hereditary optic neuropathy: Bilateral improvement of visual acuity following gene therapy by unilateral injection

Gene Therapies for the Treatment of Leber Hereditary Optic Neuropathy

Cross-Sectional Analysis of Baseline Visual Parameters in Subjects Recruited Into the RESCUE and REVERSE ND4-LHON Gene Therapy Studies

New antiplatelet agents in the treatment of acute coronary syndromes

Study design and baseline characteristics for the reflect gene therapy trial ofm.11778g>A/ND4-LHON

Absence of lenadogene nolparvovec DNA in a brain tumor biopsy from a patient in the REVERSE clinical study, a case report

Diagnostic value of fundus examination in familial adenomatous polyposis

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