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Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

The New England journal of medicine, 2017-07, Vol.377 (3), p.222-232

2017

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Geometric part error and material property profile separation technique of the additively manufactured and post-processed rods

Review of scientific instruments, 2023-03, Vol.94 (3)

2023

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Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data

ESC Heart Failure, 2021-02, Vol.8 (1), p.652-661

2021

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The Bcl6-SMRT/NCoR Cistrome Represses Inflammation to Attenuate Atherosclerosis

Cell metabolism, 2012-04, Vol.15 (4), p.554-562

2012

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Addressing unmet medical needs in type 2 diabetes: a narrative review of drugs under development

Current diabetes reviews, 2015-01, Vol.11 (1), p.17-31

2015

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Addressing Unmet Medical Needs in Type 1 Diabetes: A Review of Drugs Under Development

Current diabetes reviews, 2017-01, Vol.13 (3), p.300-314

2017

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Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia

Nucleic acid therapeutics, 2020-04, Vol.30 (2), p.94-103

2020

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Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene

American journal of physiology. Heart and circulatory physiology, 2014-04, Vol.306 (7), p.H1001-H1010

2014

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Evolution of Influenza A(H3N2) Viruses in 2 Consecutive Seasons of Genomic Surveillance, 2021–2023

Open forum infectious diseases, 2023-12, Vol.10 (12), p.ofad577

2023

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Mechanical Properties of Ni Sn and Cu Sn Determined by Inverse Method

IEEE transactions on components and packaging technologies, 2008-06, Vol.31 (2), p.503-508

2008

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Structure-Function Analysis of the Heat Shock Factor-binding Protein Reveals a Protein Composed Solely of a Highly Conserved and Dynamic Coiled-coil Trimerization Domain

The Journal of biological chemistry, 2002-01, Vol.277 (1), p.735-745

2002

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Prevalence of healthcare conditions and services used by patients with myotonic dystrophy (DM1 and DM2) prior to diagnosis; a real-world data analysis (P14-13.003)

Neurology, 2022-05, Vol.98 (18_supplement)

2022

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Rationale and Design of NEURO-TTRansform, a Phase 3 Study to Evaluate the Efficacy and Safety of AKCEA-TTR-LRx (ION-682884) in Patients with Hereditary Transthyretin-Mediated Amyloid Polyneuropathy (2240)

Neurology, 2020-04, Vol.94 (15_supplement)

2020

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Rationale and Design of a Phase 3 Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

Blood, 2019-11, Vol.134 (Supplement_1), p.5764-5764

2019

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Phase 1 Investigation of a Ligand-Conjugated Antisense Oligonucleotide with Increased Potency for the Treatment of Transthyretin Amyloidosis

Journal of cardiac failure, 2019-08, Vol.25 (8), p.S80-S81

2019

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Antisense Inhibition of Glucagon Receptor by IONIS-GCGRRx Improves Type 2 Diabetes Without Increase in Hepatic Glycogen Content in Patients With Type 2 Diabetes on Stable Metformin Therapy

Diabetes care, 2019-04, Vol.42 (4), p.585-593

2019

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Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-[delta] gene

American journal of physiology. Heart and circulatory physiology, 2014-04, Vol.306 (7), p.H1001

2014

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Antisense Inhibition of Glucagon Receptor by IONIS-GCGR Rx Improves Type 2 Diabetes Without Increase in Hepatic Glycogen Content in Patients With Type 2 Diabetes on Stable Metformin Therapy

Diabetes care, 2019-02

2019

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Heterokaryons of cardiac myocytes and fibroblasts reveal the lack of dominance of the cardiac muscle phenotype

Molecular and Cellular Biology, 1994-06, Vol.14 (6), p.4269-4279

1994

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Myotonic Dystrophy Patient Journey: Increased Use of Healthcare Resources in the Year Prior to Diagnosis as Evidenced by Insurance Claims

International Journal of Rare Diseases & Orphan Drugs, 2023-12, Vol.6 (2), p.1-11

2023

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Thermal modeling of workpiece temperature and distortion in MQL deep-hole drilling

Tai, Li-Jung

2011

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The Expression of GPIHBP1, an Endothelial Cell Binding Site for Lipoprotein Lipase and Chylomicrons, Is Induced by Peroxisome Proliferator-Activated Receptor-γ

Molecular endocrinology (Baltimore, Md.), 2008-11, Vol.22 (11), p.2496-2504

2008

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Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

Geometric part error and material property profile separation technique of the additively manufactured and post-processed rods

Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data

The Bcl6-SMRT/NCoR Cistrome Represses Inflammation to Attenuate Atherosclerosis

Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-LRx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

Addressing unmet medical needs in type 2 diabetes: a narrative review of drugs under development

Addressing Unmet Medical Needs in Type 1 Diabetes: A Review of Drugs Under Development

Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia

Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene

Evolution of Influenza A(H3N2) Viruses in 2 Consecutive Seasons of Genomic Surveillance, 2021–2023

Mechanical Properties of Ni Sn and Cu Sn Determined by Inverse Method

Structure-Function Analysis of the Heat Shock Factor-binding Protein Reveals a Protein Composed Solely of a Highly Conserved and Dynamic Coiled-coil Trimerization Domain

Prevalence of healthcare conditions and services used by patients with myotonic dystrophy (DM1 and DM2) prior to diagnosis; a real-world data analysis (P14-13.003)

Preliminary Assessment of the Phase 1/2 Clinical Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AOC 1001 Administered Intravenously to Adult Patients with Myotonic Dystrophy Type 1 (DM1) (MARINA) (S48.002)

Study Design of AOC 1001-CS1, a Phase 1/2 Clinical Trial Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AOC 1001 Administered Intravenously to Adult Patients with Myotonic Dystrophy Type 1 (DM1) (MARINA) (S23.006)

Rationale and Design of NEURO-TTRansform, a Phase 3 Study to Evaluate the Efficacy and Safety of AKCEA-TTR-LRx (ION-682884) in Patients with Hereditary Transthyretin-Mediated Amyloid Polyneuropathy (2240)

Rationale and Design of a Phase 3 Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)

Phase 1 Investigation of a Ligand-Conjugated Antisense Oligonucleotide with Increased Potency for the Treatment of Transthyretin Amyloidosis

Antisense Inhibition of Glucagon Receptor by IONIS-GCGRRx Improves Type 2 Diabetes Without Increase in Hepatic Glycogen Content in Patients With Type 2 Diabetes on Stable Metformin Therapy

Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-[delta] gene

Antisense Inhibition of Glucagon Receptor by IONIS-GCGR Rx Improves Type 2 Diabetes Without Increase in Hepatic Glycogen Content in Patients With Type 2 Diabetes on Stable Metformin Therapy

Heterokaryons of cardiac myocytes and fibroblasts reveal the lack of dominance of the cardiac muscle phenotype

Myotonic Dystrophy Patient Journey: Increased Use of Healthcare Resources in the Year Prior to Diagnosis as Evidenced by Insurance Claims

Thermal modeling of workpiece temperature and distortion in MQL deep-hole drilling

The Expression of GPIHBP1, an Endothelial Cell Binding Site for Lipoprotein Lipase and Chylomicrons, Is Induced by Peroxisome Proliferator-Activated Receptor-γ

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