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Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models

PloS one, 2022-01, Vol.17 (1), p.e0256512-e0256512

2022

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Est1p as a Cell Cycle-Regulated Activator of Telomere-Bound Telomerase

Science (American Association for the Advancement of Science), 2002-08, Vol.297 (5583), p.1023-1026

2002

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Role of GPR81 in lactate-mediated reduction of adipose lipolysis

Biochemical and biophysical research communications, 2008-12, Vol.377 (3), p.987-991

2008

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Discovery of a brain-sparing GIRK1/4 inhibitor for pharmacological cardioversion of atrial fibrillation

Bioorganic & medicinal chemistry letters, 2023-04, Vol.85, p.129237-129237, Article 129237

2023

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Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib

Arteriosclerosis, thrombosis, and vascular biology, 2010-07, Vol.30 (7), p.1430-1438

2010

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Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppression

Science translational medicine, 2012-08, Vol.4 (148), p.148ra115

2012

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(d)-β-Hydroxybutyrate Inhibits Adipocyte Lipolysis via the Nicotinic Acid Receptor PUMA-G

The Journal of biological chemistry, 2005-07, Vol.280 (29), p.26649-26652

2005

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Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G)

Journal of lipid research, 2009-05, Vol.50 (5), p.908-914

2009

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The discovery of high affinity agonists of GPR109a with reduced serum shift and improved ADME properties

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2721-2724

2011

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Cell cycle-dependent regulation of yeast telomerase by Ku

Nature structural & molecular biology, 2004-12, Vol.11 (12), p.1198-1205

2004

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The role of the Mre11-Rad50-Xrs2 complex in telomerase- mediated lengthening of Saccharomyces cerevisiae telomeres

Current biology, 2001-09, Vol.11 (17), p.1328-1335

2001

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Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (18), p.4948-4951

2008

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Catching them before they fall: a Vygotskian approach to transitioning students from high school to university

Higher education research and development, 2016-07, Vol.35 (4), p.698-711

2016

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Molecular modeling aided design of nicotinic acid receptor GPR109A agonists

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (18), p.4963-4967

2008

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GPR109a agonists. Part 2: Pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a

Bioorganic & medicinal chemistry letters, 2010-08, Vol.20 (15), p.4472-4474

2010

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(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic Acid (MK-1903): A Potent GPR109a Agonist that Lowers Free Fatty Acids in Humans

Journal of medicinal chemistry, 2012-04, Vol.55 (8), p.3644-3666

2012

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3-(1H-Tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): A Partial Agonist of the Nicotinic Acid Receptor, G-Protein Coupled Receptor 109a, with Antilipolytic but No Vasodilatory Activity in Mice

Journal of medicinal chemistry, 2008-08, Vol.51 (16), p.5101-5108

2008

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University Aspirational Pathways for Metropolitan and Regional Students: Implications for Supporting School-University Outreach Partnerships

Australian and international journal of rural education, 2018, Vol.28 (1), p.87

2018

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Discovery of Novel Tricyclic Full Agonists for the G-Protein-Coupled Niacin Receptor 109A with Minimized Flushing in Rats

Journal of medicinal chemistry, 2009-04, Vol.52 (8), p.2587-2602

2009

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GPR109a agonists. Part 1: 5-Alkyl and 5-aryl-pyrazole–tetrazoles as agonists of the human orphan G-protein coupled receptor GPR109a

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (8), p.2121-2124

2009

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Telomerase: what are the Est proteins doing?

Current opinion in cell biology, 2003-06, Vol.15 (3), p.275-280

2003

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Discovery of a Biaryl Cyclohexene Carboxylic Acid (MK-6892): A Potent and Selective High Affinity Niacin Receptor Full Agonist with Reduced Flushing Profiles in Animals as a Preclinical Candidate

Journal of medicinal chemistry, 2010-03, Vol.53 (6), p.2666-2670

2010

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Developing conceptual understandings of the capacity to aspire for higher education

Issues in educational research, 2014-01, Vol.24 (2), p.174-189

2014

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The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species

Journal of lipid research, 2011-06, Vol.52 (6), p.1150-1161

2011

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Discovery of Biaryl Anthranilides as Full Agonists for the High Affinity Niacin Receptor

Journal of medicinal chemistry, 2007-12, Vol.50 (25), p.6303-6306

2007

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Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models

Est1p as a Cell Cycle-Regulated Activator of Telomere-Bound Telomerase

Role of GPR81 in lactate-mediated reduction of adipose lipolysis

Discovery of a brain-sparing GIRK1/4 inhibitor for pharmacological cardioversion of atrial fibrillation

Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib

Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppression

(d)-β-Hydroxybutyrate Inhibits Adipocyte Lipolysis via the Nicotinic Acid Receptor PUMA-G

Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G)

The discovery of high affinity agonists of GPR109a with reduced serum shift and improved ADME properties

Cell cycle-dependent regulation of yeast telomerase by Ku

The role of the Mre11-Rad50-Xrs2 complex in telomerase- mediated lengthening of Saccharomyces cerevisiae telomeres

Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A

Catching them before they fall: a Vygotskian approach to transitioning students from high school to university

Molecular modeling aided design of nicotinic acid receptor GPR109A agonists

GPR109a agonists. Part 2: Pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a

(1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic Acid (MK-1903): A Potent GPR109a Agonist that Lowers Free Fatty Acids in Humans

3-(1H-Tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): A Partial Agonist of the Nicotinic Acid Receptor, G-Protein Coupled Receptor 109a, with Antilipolytic but No Vasodilatory Activity in Mice

University Aspirational Pathways for Metropolitan and Regional Students: Implications for Supporting School-University Outreach Partnerships

Discovery of Novel Tricyclic Full Agonists for the G-Protein-Coupled Niacin Receptor 109A with Minimized Flushing in Rats

GPR109a agonists. Part 1: 5-Alkyl and 5-aryl-pyrazole–tetrazoles as agonists of the human orphan G-protein coupled receptor GPR109a

Telomerase: what are the Est proteins doing?

Discovery of a Biaryl Cyclohexene Carboxylic Acid (MK-6892): A Potent and Selective High Affinity Niacin Receptor Full Agonist with Reduced Flushing Profiles in Animals as a Preclinical Candidate

Developing conceptual understandings of the capacity to aspire for higher education

The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species

Discovery of Biaryl Anthranilides as Full Agonists for the High Affinity Niacin Receptor

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