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Mechanistic Multilayer Quantitative Model for Nonlinear Pharmacokinetics, Target Occupancy and Pharmacodynamics (PK/TO/PD) Relationship of D-Amino Acid Oxidase Inhibitor, TAK-831 in Mice

Pharmaceutical research, 2020-08, Vol.37 (8), Article 164

2020

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Radiographic Localization Study of a Novel Potassium-Competitive Acid Blocker, Vonoprazan, in the Rat Gastric Mucosa

Digestive diseases and sciences, 2016-07, Vol.61 (7), p.1888-1894

2016

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Characteristics of the Novel Potassium-Competitive Acid Blocker Vonoprazan Fumarate (TAK-438)

Advances in therapy, 2016-07, Vol.33 (7), p.1140-1157

2016

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Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model

European journal of pharmacology, 2018-06, Vol.828, p.126-134

2018

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Electrically Stimulated Antagonist Muscle Contraction Increased Muscle Mass and Bone Mineral Density of One Astronaut - Initial Verification on the International Space Station

PloS one, 2015-08, Vol.10 (8), p.e0134736-e0134736

2015

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The effect of rotator cuff physical exercise combined with electrically stimulated antagonist on shoulder rotator cuff strength

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2022-01, Vol.27 (1), p.126-130

2022

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Effect of Cycling Exercise Resisting Electrically Stimulated Antagonist Muscle Contractions in Healthy Males

Metabolites, 2023-04, Vol.13 (5), p.604

2023

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Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK‐448, for its anti‐tumor efficacy in a rat xenograft model

Biopharmaceutics & drug disposition, 2020-07, Vol.41 (7), p.283-294

2020

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Disposition and metabolism of TAK-438 (vonoprazan fumarate), a novel potassium-competitive acid blocker, in rats and dogs

Xenobiotica, 2017-03, Vol.47 (3), p.255-266

2017

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Cycling Exercise with Electrical Stimulation of Antagonist Muscles Increases Plasma Growth Hormone and IL-6

The Tohoku Journal of Experimental Medicine, 2015, Vol.237(3), pp.209-217

2015

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Correction: Electrically Stimulated Antagonist Muscle Contraction Increased Muscle Mass and Bone Mineral Density of One Astronaut--Initial Verification on the International Space Station

PloS one, 2015-09, Vol.10 (9), p.e0138519-e0138519

2015

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Pharmacokinetic and pharmacodynamic modeling of hedgehog inhibitor TAK-441 for the inhibition of Gli1 messenger RNA expression and antitumor efficacy in xenografted tumor model mice

Drug metabolism and disposition, 2013-04, Vol.41 (4), p.727-734

2013

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Absorption, distribution, metabolism and excretion of peginesatide, a novel erythropoiesis-stimulating agent, in rats

Xenobiotica, 2012-07, Vol.42 (7), p.660-670

2012

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Cycling exercise to resist electrically stimulated antagonist increases oxygen uptake in males: pilot study

Journal of rehabilitation research and development, 2013-01, Vol.50 (4), p.545-554

2013

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Increasing Muscle Strength and Mass of Thigh in Elderly People with the Hybrid-Training Method of Electrical Stimulation and Volitional Contraction

The Tohoku Journal of Experimental Medicine, 2010, Vol.221(1), pp.77-85

2010

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Highly Potent Inhibition of Human Immunodeficiency Virus Type 1 Replication by TAK-220, an Orally Bioavailable Small-Molecule CCR5 Antagonist

Antimicrobial Agents and Chemotherapy, 2005-08, Vol.49 (8), p.3474-3482

2005

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Metabolic Fate of Sipoglitazar a Novel Oral PPAR Agonist with Activities for PPAR-γ, -α and -δ, in Rats and Monkeys and Comparison with Humans In Vitro

Drug metabolism and pharmacokinetics, 2012, Vol.27 (2), p.223-231

2012

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Improvement in Knee Extension Strength through Training by Means of Combined Electrical Stimulation and Voluntary Muscle Contraction

The Tohoku Journal of Experimental Medicine, 2006, Vol.209(1), pp.33-40

2006

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Soticlestat in Vitro Metabolism and Drug-drug Interactions: Comprehensive Investigations Display Minimal Notable Interactions (P9-1.012)

Neurology, 2024-04, Vol.102 (17_supplement_1)

2024

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Development of a Training Method for Weightless Environment Using Both Electrical Stimulation and Voluntary Muscle Contraction

The Tohoku Journal of Experimental Medicine, 2010, Vol.220(1), pp.83-93

2010

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Electrically stimulating antagonist muscles could improve strength in older men: A pilot study

Gerontechnology, 2015-08, Vol.13 (4), p.420-425

2015

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A Study of Simple Adaptive Control System of Electrical Stimulation for Upper Limb Motion

Transactions of Japanese Society for Medical and Biological Engineering, 2013, Vol.51(Supplement), pp.M-52-M-52

2013

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Bone morphology and physical characteristics of the pro-cyclist hip joint

International orthopaedics, 2024-07, Vol.48 (7), p.1879-1886

2024

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A Standing Low-frequency Vibration Exercise Device for Improving Balance in Community-dwelling Older Adults: A Single-blind Randomized Controlled Trial

Physical Therapy Research, 2023, pp.E10192

2023

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Metabolic Fate of Sipoglitazar, a Novel Oral PPAR Agonist with Activities for PPAR-γ,-α and -δ, in Rats and Monkeys and Comparison with Humans In Vitro

DRUG METABOLISM AND PHARMACOKINETICS, 2012-04, Vol.27 (2), p.223-231

2012

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Mechanistic Multilayer Quantitative Model for Nonlinear Pharmacokinetics, Target Occupancy and Pharmacodynamics (PK/TO/PD) Relationship of D-Amino Acid Oxidase Inhibitor, TAK-831 in Mice

Radiographic Localization Study of a Novel Potassium-Competitive Acid Blocker, Vonoprazan, in the Rat Gastric Mucosa

Characteristics of the Novel Potassium-Competitive Acid Blocker Vonoprazan Fumarate (TAK-438)

Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model

Electrically Stimulated Antagonist Muscle Contraction Increased Muscle Mass and Bone Mineral Density of One Astronaut - Initial Verification on the International Space Station

The effect of rotator cuff physical exercise combined with electrically stimulated antagonist on shoulder rotator cuff strength

Effect of Cycling Exercise Resisting Electrically Stimulated Antagonist Muscle Contractions in Healthy Males

Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK‐448, for its anti‐tumor efficacy in a rat xenograft model

Disposition and metabolism of TAK-438 (vonoprazan fumarate), a novel potassium-competitive acid blocker, in rats and dogs

Cycling Exercise with Electrical Stimulation of Antagonist Muscles Increases Plasma Growth Hormone and IL-6

Correction: Electrically Stimulated Antagonist Muscle Contraction Increased Muscle Mass and Bone Mineral Density of One Astronaut--Initial Verification on the International Space Station

Pharmacokinetic and pharmacodynamic modeling of hedgehog inhibitor TAK-441 for the inhibition of Gli1 messenger RNA expression and antitumor efficacy in xenografted tumor model mice

Absorption, distribution, metabolism and excretion of peginesatide, a novel erythropoiesis-stimulating agent, in rats

Cycling exercise to resist electrically stimulated antagonist increases oxygen uptake in males: pilot study

Increasing Muscle Strength and Mass of Thigh in Elderly People with the Hybrid-Training Method of Electrical Stimulation and Volitional Contraction

Highly Potent Inhibition of Human Immunodeficiency Virus Type 1 Replication by TAK-220, an Orally Bioavailable Small-Molecule CCR5 Antagonist

Metabolic Fate of Sipoglitazar a Novel Oral PPAR Agonist with Activities for PPAR-γ, -α and -δ, in Rats and Monkeys and Comparison with Humans In Vitro

Improvement in Knee Extension Strength through Training by Means of Combined Electrical Stimulation and Voluntary Muscle Contraction

Soticlestat in Vitro Metabolism and Drug-drug Interactions: Comprehensive Investigations Display Minimal Notable Interactions (P9-1.012)

Development of a Training Method for Weightless Environment Using Both Electrical Stimulation and Voluntary Muscle Contraction

Electrically stimulating antagonist muscles could improve strength in older men: A pilot study

A Study of Simple Adaptive Control System of Electrical Stimulation for Upper Limb Motion

Bone morphology and physical characteristics of the pro-cyclist hip joint

A Standing Low-frequency Vibration Exercise Device for Improving Balance in Community-dwelling Older Adults: A Single-blind Randomized Controlled Trial

Metabolic Fate of Sipoglitazar, a Novel Oral PPAR Agonist with Activities for PPAR-γ,-α and -δ, in Rats and Monkeys and Comparison with Humans In Vitro

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