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The Mediator complex: a central integrator of transcription

Nature reviews. Molecular cell biology, 2015-03, Vol.16 (3), p.155

2015

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Structure and mechanism of the RNA polymerase II transcription machinery

Genes & development, 2020-04, Vol.34 (7-8), p.465-488

2020

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The human Mediator complex: a versatile, genome-wide regulator of transcription

Trends in biochemical sciences (Amsterdam. Regular ed.), 2010-06, Vol.35 (6), p.315-322

Taatjes, Dylan J.

2010

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The Mediator kinase module: an interface between cell signaling and transcription

Trends in biochemical sciences (Amsterdam. Regular ed.), 2022-04, Vol.47 (4), p.314-327

2022

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The essential and multifunctional TFIIH complex

Protein science, 2018-06, Vol.27 (6), p.1018-1037

2018

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CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response

Immunity (Cambridge, Mass.), 2013-02, Vol.38 (2), p.250-262

2013

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The Mediator complex and transcription regulation

Critical reviews in biochemistry and molecular biology, 2013-11, Vol.48 (6), p.575-608

2013

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Structural visualization of key steps in human transcription initiation

Nature (London), 2013-03, Vol.495 (7442), p.481-486

2013

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Pol II phosphorylation regulates a switch between transcriptional and splicing condensates

Nature (London), 2019-08, Vol.572 (7770), p.543-548

2019

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Regulatory functions of the Mediator kinases CDK8 and CDK19

Transcription, 2019-03, Vol.10 (2), p.76-90

2019

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Mediator and cohesin connect gene expression and chromatin architecture

Nature (London), 2010-09, Vol.467 (7314), p.430-435

2010

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The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation

PLoS biology, 2021-08, Vol.19 (8), p.e3001364-e3001364

2021

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Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH

Molecular cell, 2015-09, Vol.59 (5), p.794-806

2015

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Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics

Cell reports (Cambridge), 2016-04, Vol.15 (2), p.436-450

2016

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Mediator kinase inhibition further activates super-enhancer-associated genes in AML

Nature (London), 2015-10, Vol.526 (7572), p.273-276

2015

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FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2

Genes & development, 2012-12, Vol.26 (24), p.2690-2695

2012

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Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly

PLoS biology, 2011-03, Vol.9 (3), p.e1000603-e1000603

2011

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CDK8 is a positive regulator of transcriptional elongation within the serum response network

Nature structural & molecular biology, 2010-02, Vol.17 (2), p.194

2010

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Activator-Mediator binding regulates Mediator-cofactor interactions

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (25), p.11283-11288

2010

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Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications

Cell reports (Cambridge), 2017-08, Vol.20 (5), p.1173-1186

2017

Volltextzugriff (PDF)

Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription

Journal of molecular biology, 2022-01, Vol.434 (1), p.167216-167216, Article 167216

2022

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The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair

Scientific reports, 2019-04, Vol.9 (1), p.6539-6539, Article 6539

2019

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The Human CDK8 Subcomplex Is a Histone Kinase That Requires Med12 for Activity and Can Function Independently of Mediator

Molecular and Cellular Biology, 2009-02, Vol.29 (3), p.650-661

2009

Volltextzugriff (PDF)

p53 activates transcription by directing structural shifts in Mediator

Nature structural & molecular biology, 2010-06, Vol.17 (6), p.753

2010

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RNA Polymerase II Transcription

Journal of molecular biology, 2021-07, Vol.433 (14), p.167037-167037, Article 167037

Taatjes, Dylan J.

2021

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The Mediator complex: a central integrator of transcription

Structure and mechanism of the RNA polymerase II transcription machinery

The human Mediator complex: a versatile, genome-wide regulator of transcription

The Mediator kinase module: an interface between cell signaling and transcription

The essential and multifunctional TFIIH complex

CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response

The Mediator complex and transcription regulation

Structural visualization of key steps in human transcription initiation

Pol II phosphorylation regulates a switch between transcriptional and splicing condensates

Regulatory functions of the Mediator kinases CDK8 and CDK19

Mediator and cohesin connect gene expression and chromatin architecture

The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation

Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH

Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics

Mediator kinase inhibition further activates super-enhancer-associated genes in AML

FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2

Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly

CDK8 is a positive regulator of transcriptional elongation within the serum response network

Activator-Mediator binding regulates Mediator-cofactor interactions

Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications

Merging Established Mechanisms with New Insights: Condensates, Hubs, and the Regulation of RNA Polymerase II Transcription

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair

The Human CDK8 Subcomplex Is a Histone Kinase That Requires Med12 for Activity and Can Function Independently of Mediator

p53 activates transcription by directing structural shifts in Mediator

RNA Polymerase II Transcription

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