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Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors

British journal of cancer, 2009-11, Vol.101 (10), p.1717-1723

2009

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Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

Nature (London), 1999-01, Vol.397 (6715), p.176-180

1999

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Determination of the aggregation number of detergent micelles using steady-state fluorescence quenching

Biophysical journal, 1993-05, Vol.64 (5), p.1580-1587

1993

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The in vitro Ejection of Zinc from Human Immunodeficiency Virus (HIV) Type 1 Nucleocapsid Protein by Disulfide Benzamides with Cellular Anti-HIV Activity

Proceedings of the National Academy of Sciences - PNAS, 1996-02, Vol.93 (3), p.969-973

1996

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The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein zinc ejection activity of disulfide benzamides and benzisothiazolones: correlation with anti-HIV and virucidal activities

Antimicrobial Agents and Chemotherapy, 1997-02, Vol.41 (2), p.394-400

1997

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5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities: Potent Nonpeptidic Inhibitors of HIV Protease

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.843-858

2000

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Residence Time of Receptor−Ligand Complexes and Its Effect on Biological Function

Biochemistry (Easton), 2008-05, Vol.47 (20), p.5481-5492

2008

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Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral Activity

Journal of medicinal chemistry, 1997-11, Vol.40 (23), p.3707-3711

1997

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4-Hydroxy-5,6-dihydropyrones. 2. Potent Non-Peptide Inhibitors of HIV Protease

Journal of medicinal chemistry, 1997-11, Vol.40 (23), p.3781-3792

1997

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Competitive Inhibition of HIV-1 Protease by 4-Hydroxy-benzopyran-2-ones and by 4-Hydroxy-6-phenylpyran-2-ones

Biochemical and biophysical research communications, 1994-05, Vol.200 (3), p.1658-1664

1994

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Nonpeptidic HIV protease inhibitors possessing excellent antiviral activities and therapeutic indices. PD 178390 : A lead HIV protease inhibitor

Bioorganic & medicinal chemistry, 1999-12, Vol.7 (12), p.2775-2800

1999

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Adenine nucleotide translocase greatly increases the partition of trinitrophenyl-ATP into reduced Triton X-100 micelles

Biophysical journal, 1992-10, Vol.63 (4), p.1071-1080

1992

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Novel Series of Achiral, Low Molecular Weight, and Potent HIV-1 Protease Inhibitors

Journal of the American Chemical Society, 1994-07, Vol.116 (15), p.6989-6990

1994

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Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydropyran-2-ones possessing a novel and achiral 3-(2- t-butyl-5-methyl-4-sulfamate)phenylthio moiety

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (15), p.2217-2222

1999

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A comparative study of succinate-supported respiration and ATP/ADP translocation in liver mitochondria from adult and old rats

Mechanisms of ageing and development, 1991-06, Vol.59 (1), p.177-188

1991

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Competitive Inhibition of HIV-1 Protease by Warfarin Derivatives

Biochemical and biophysical research communications, 1994-05, Vol.201 (1), p.290-294

1994

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A Novel Nonpeptide HIV-1 Protease Inhibitor: Elucidation of the Binding Mode and Its Application in the Design of Related Analogs

Journal of medicinal chemistry, 1994-08, Vol.37 (17), p.2664-2677

1994

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Substrate-Based Design of the First Class of Angiotensin-Converting Enzyme-Related Carboxypeptidase (ACE2) Inhibitors

Journal of the American Chemical Society, 2002-10, Vol.124 (40), p.11852-11853

2002

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Inhibitors of HIV protease: Unique non-peptide active site templates

Journal of molecular recognition, 1996-03, Vol.9 (2), p.139-142

1996

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A new class of anti-HIV-1 agents targeted toward the nucleocapsid protein NCp7: The 2,2′-dithiobisbenzamides

Bioorganic & medicinal chemistry, 1997-03, Vol.5 (3), p.569-579

1997

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Helicobacter pylori 3-deoxy- D- manno-octulosonate-8-phosphate (KDO-8-P) synthase is a zinc-metalloenzyme

Biochimica et biophysica acta, 2002-02, Vol.1594 (2), p.297-306

2002

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Nonpeptidic HIV protease inhibitors: 6-alkyl-5, 6-dihydropyran-2-ones possessing achiral 3-(4-amino/carboxamide-2- t-butyl, 5-methylphenyl thio) moiety: Antiviral activities and pharmacokinetic properties

Bioorganic & medicinal chemistry letters, 1999-06, Vol.9 (11), p.1481-1486

1999

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Discovery and optimization of nonpeptide HIV-1 protease inhibitors

Bioorganic & medicinal chemistry, 1996-09, Vol.4 (9), p.1401-1410

1996

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An assay for Fe(II)/2-oxoglutarate-dependent dioxygenases by enzyme-coupled detection of succinate formation

Analytical biochemistry, 2006-06, Vol.353 (1), p.69-74

2006

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Enzymatic Characterization of the Pancreatic Islet-specific Glucose-6-Phosphatase-related Protein (IGRP)

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.13976-13983

2004

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Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors

Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

Determination of the aggregation number of detergent micelles using steady-state fluorescence quenching

The in vitro Ejection of Zinc from Human Immunodeficiency Virus (HIV) Type 1 Nucleocapsid Protein by Disulfide Benzamides with Cellular Anti-HIV Activity

The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein zinc ejection activity of disulfide benzamides and benzisothiazolones: correlation with anti-HIV and virucidal activities

5,6-Dihydropyran-2-ones Possessing Various Sulfonyl Functionalities: Potent Nonpeptidic Inhibitors of HIV Protease

Residence Time of Receptor−Ligand Complexes and Its Effect on Biological Function

Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral Activity

4-Hydroxy-5,6-dihydropyrones. 2. Potent Non-Peptide Inhibitors of HIV Protease

Competitive Inhibition of HIV-1 Protease by 4-Hydroxy-benzopyran-2-ones and by 4-Hydroxy-6-phenylpyran-2-ones

Nonpeptidic HIV protease inhibitors possessing excellent antiviral activities and therapeutic indices. PD 178390 : A lead HIV protease inhibitor

Adenine nucleotide translocase greatly increases the partition of trinitrophenyl-ATP into reduced Triton X-100 micelles

Novel Series of Achiral, Low Molecular Weight, and Potent HIV-1 Protease Inhibitors

Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydropyran-2-ones possessing a novel and achiral 3-(2- t-butyl-5-methyl-4-sulfamate)phenylthio moiety

A comparative study of succinate-supported respiration and ATP/ADP translocation in liver mitochondria from adult and old rats

Competitive Inhibition of HIV-1 Protease by Warfarin Derivatives

A Novel Nonpeptide HIV-1 Protease Inhibitor: Elucidation of the Binding Mode and Its Application in the Design of Related Analogs

Substrate-Based Design of the First Class of Angiotensin-Converting Enzyme-Related Carboxypeptidase (ACE2) Inhibitors

Inhibitors of HIV protease: Unique non-peptide active site templates

A new class of anti-HIV-1 agents targeted toward the nucleocapsid protein NCp7: The 2,2′-dithiobisbenzamides

Helicobacter pylori 3-deoxy- D- manno-octulosonate-8-phosphate (KDO-8-P) synthase is a zinc-metalloenzyme

Nonpeptidic HIV protease inhibitors: 6-alkyl-5, 6-dihydropyran-2-ones possessing achiral 3-(4-amino/carboxamide-2- t-butyl, 5-methylphenyl thio) moiety: Antiviral activities and pharmacokinetic properties

Discovery and optimization of nonpeptide HIV-1 protease inhibitors

An assay for Fe(II)/2-oxoglutarate-dependent dioxygenases by enzyme-coupled detection of succinate formation

Enzymatic Characterization of the Pancreatic Islet-specific Glucose-6-Phosphatase-related Protein (IGRP)

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