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The impact of the COVID-19 pandemic on perceived publication pressure among academic researchers in Canada

PloS one, 2022-06, Vol.17 (6), p.e0269743-e0269743

2022

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Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (36), p.14610-14615

2013

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Cofilin nuclear-cytoplasmic shuttling affects cofilin-actin rod formation during stress

Journal of cell science, 2012-09, Vol.125 (Pt 17), p.3977-3988

2012

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Development of a knowledge translation platform for ataxia: Impact on readers and volunteer contributors

PloS one, 2020-09, Vol.15 (9), p.e0238512-e0238512

2020

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Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (9), p.3528-3533

2012

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A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy

Autophagy, 2008-01, Vol.4 (1), p.91-93

2008

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PAM-flexible genome editing with an engineered chimeric Cas9

Nature communications, 2023-10, Vol.14 (1), p.6175-6175, Article 6175

2023

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When the labs closed: graduate students’ and postdoctoral fellows’ experiences of disrupted research during the COVID-19 pandemic

Facets (Ottawa), 2021-01, Vol.6 (1), p.966-997

2021

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Mod3D: A low-cost, flexible modular system of live-cell microscopy chambers and holders

PloS one, 2022-06, Vol.17 (6), p.e0269345-e0269345

2022

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Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

Human molecular genetics, 2011-05, Vol.20 (10), p.1937-1951

2011

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Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

The FEBS journal, 2008-09, Vol.275 (17), p.4252-4262

2008

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Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions

Human molecular genetics, 2014-05, Vol.23 (9), p.2324-2338

2014

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Using FLIM-FRET to measure conformational changes of transglutaminase type 2 in live cells

PloS one, 2012-08, Vol.7 (8), p.e44159-e44159

2012

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The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals

Molecular and Cellular Biology, 1999-02, Vol.19 (2), p.1210-1217

1999

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Single Cell Technologies Define New Therapeutic Avenues for Huntington’s Disease

Neuron (Cambridge, Mass.), 2020-09, Vol.107 (5), p.768-769

2020

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Functional characterization of variants of unknown significance in a spinocerebellar ataxia patient using an unsupervised machine learning pipeline

Human genome variation, 2022-04, Vol.9 (1), p.10-10, Article 10

2022

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DNA Repair in Huntington's Disease and Spinocerebellar Ataxias: Somatic Instability and Alternative Hypotheses

Journal of Huntington's disease, 2021-01, Vol.10 (1), p.165-173

2021

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Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

Communications biology, 2021-12, Vol.4 (1), p.1374-16, Article 1374

2021

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DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants

Cell reports (Cambridge), 2016-11, Vol.17 (7), p.1892-1904

2016

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Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin

The Journal of biological chemistry, 2005-10, Vol.280 (41), p.34840-34848

2005

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RNA association and nucleocytoplasmic shuttling by ataxin-1

Journal of cell science, 2005-01, Vol.118 (Pt 1), p.233-242

2005

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Re-expression of TSLC1 in a non-small-cell lung cancer cell line induces apoptosis and inhibits tumor growth

Oncogene, 2004-07, Vol.23 (33), p.5632-5642

2004

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In Vivo Formation of Protein Based Aqueous Microcompartments

Journal of the American Chemical Society, 2009-07, Vol.131 (25), p.9094-9099

2009

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Proteolytic Cleavage of Ataxin-7 by Caspase-7 Modulates Cellular Toxicity and Transcriptional Dysregulation

The Journal of biological chemistry, 2007-10, Vol.282 (41), p.30150-30160

2007

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Determination of the Topology of the Hydrophobic Segment of Mammalian Diacylglycerol Kinase Epsilon in a Cell Membrane and Its Relationship to Predictions from Modeling

Journal of molecular biology, 2008-11, Vol.383 (4), p.797-809

2008

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The impact of the COVID-19 pandemic on perceived publication pressure among academic researchers in Canada

Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin

Cofilin nuclear-cytoplasmic shuttling affects cofilin-actin rod formation during stress

Development of a knowledge translation platform for ataxia: Impact on readers and volunteer contributors

Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice

A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy

PAM-flexible genome editing with an engineered chimeric Cas9

When the labs closed: graduate students’ and postdoctoral fellows’ experiences of disrupted research during the COVID-19 pandemic

Mod3D: A low-cost, flexible modular system of live-cell microscopy chambers and holders

Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions

Using FLIM-FRET to measure conformational changes of transglutaminase type 2 in live cells

The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals

Single Cell Technologies Define New Therapeutic Avenues for Huntington’s Disease

Functional characterization of variants of unknown significance in a spinocerebellar ataxia patient using an unsupervised machine learning pipeline

DNA Repair in Huntington's Disease and Spinocerebellar Ataxias: Somatic Instability and Alternative Hypotheses

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants

Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin

RNA association and nucleocytoplasmic shuttling by ataxin-1

Re-expression of TSLC1 in a non-small-cell lung cancer cell line induces apoptosis and inhibits tumor growth

In Vivo Formation of Protein Based Aqueous Microcompartments

Proteolytic Cleavage of Ataxin-7 by Caspase-7 Modulates Cellular Toxicity and Transcriptional Dysregulation

Determination of the Topology of the Hydrophobic Segment of Mammalian Diacylglycerol Kinase Epsilon in a Cell Membrane and Its Relationship to Predictions from Modeling

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