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Host―microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Nature (London), 2012-11, Vol.491 (7422), p.119-124

2012

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Nature genetics, 2008-08, Vol.40 (8), p.955-962

2008

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The Impact of NOD2 Variants on Fecal Microbiota in Crohn's Disease and Controls Without Gastrointestinal Disease

Inflammatory bowel diseases, 2018-02, Vol.24 (3), p.583-592

2018

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A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis

Nature communications, 2022-04, Vol.13 (1), p.2299-12, Article 2299

2022

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Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways

PLoS medicine, 2008-12, Vol.5 (12), p.e239-e239

2008

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Contribution of TNFSF15 gene variants to Crohn's disease susceptibility confirmed in UK population

Inflammatory bowel diseases, 2008-06, Vol.14 (6), p.733-737

2008

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Prevalence of undiagnosed axial spondyloarthritis in inflammatory bowel disease patients with chronic back pain: secondary care cross-sectional study

Rheumatology (Oxford, England), 2023-04, Vol.62 (4), p.1511-1518

2023

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HLA-DQA105 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn’s Disease

Gastroenterology (New York, N.Y. 1943), 2020-01, Vol.158 (1), p.189-199

2020

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Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

The Lancet (British edition), 2016-01, Vol.387 (10014), p.156-167

2016

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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Nature genetics, 2013-09, Vol.45 (9), p.984-994

2013

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Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

The lancet. Gastroenterology & hepatology, 2019-05, Vol.4 (5), p.341-353

2019

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HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

Nature genetics, 2014-10, Vol.46 (10), p.1131-1134

2014

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High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

Nature genetics, 2012-12, Vol.44 (12), p.1336-1340

2012

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Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

Nature genetics, 2013-06, Vol.45 (6), p.670-675

2013

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Genome-wide association study identifies eight loci associated with blood pressure

Nature genetics, 2009-06, Vol.41 (6), p.666-676

2009

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Nature, 2007-06, Vol.447 (7145), p.661-678

2007

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Common variants near MC4R are associated with fat mass, weight and risk of obesity

Nature genetics, 2008-06, Vol.40 (6), p.768-775

2008

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Thiopurine monotherapy is effective in ulcerative colitis but significantly less so in Crohn's disease: long-term outcomes for 11 928 patients in the UK inflammatory bowel disease bioresource

Gut, 2021-04, Vol.70 (4), p.677-686

2021

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Common variants at five new loci associated with early-onset inflammatory bowel disease

Nature genetics, 2009-12, Vol.41 (12), p.1335-1340

2009

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Host―microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

The Impact of NOD2 Variants on Fecal Microbiota in Crohn's Disease and Controls Without Gastrointestinal Disease

A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis

Blockage of bacterial FimH prevents mucosal inflammation associated with Crohn’s disease

Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways

Contribution of TNFSF15 gene variants to Crohn's disease susceptibility confirmed in UK population

Prevalence of undiagnosed axial spondyloarthritis in inflammatory bowel disease patients with chronic back pain: secondary care cross-sectional study

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

HLA-DQA105 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn’s Disease

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

Genome-wide association study identifies eight loci associated with blood pressure

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Thiopurine monotherapy is effective in ulcerative colitis but significantly less so in Crohn's disease: long-term outcomes for 11 928 patients in the UK inflammatory bowel disease bioresource

Common variants at five new loci associated with early-onset inflammatory bowel disease

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