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p53 and FBXW7: Sometimes Two Guardians Are Worse than One

Cancers, 2020-04, Vol.12 (4), p.985

2020

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Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer

Oncotarget, 2016-08, Vol.7 (33), p.52751-52765

2016

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Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells

Cancers, 2018-12, Vol.10 (12), p.490

2018

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Prostate cancer cell response to paclitaxel is affected by abnormally expressed securin PTTG1

Molecular cancer therapeutics, 2014-10, Vol.13 (10), p.2372-2383

2014

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Taste Discrimination after Separate Pre-Exposure and Test Sessions

Perceptual and motor skills, 2009-06, Vol.108 (3), p.782-788

2009

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Protein Phosphatase 2A Stabilizes Human Securin, Whose Phosphorylated Forms Are Degraded via the SCF Ubiquitin Ligase

Molecular and Cellular Biology, 2006-06, Vol.26 (11), p.4017-4027

2006

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Both p62/SQSTM1-HDAC6-dependent autophagy and the aggresome pathway mediate CDK1 degradation in human breast cancer

Scientific reports, 2017-08, Vol.7 (1), p.10078-10, Article 10078

2017

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Cisplatin-induced cell death increases the degradation of the MRE11-RAD50-NBS1 complex through the autophagy/lysosomal pathway

Cell death and differentiation, 2023-02, Vol.30 (2), p.488-499

2023

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SCF(FBXW7)‐mediated degradation of p53 promotes cell recovery after UV‐induced DNA damage

The FASEB journal, 2019-10, Vol.33 (10), p.11420-11430

2019

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Expression of pituitary tumor–transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)‐associated liver diseases: Evidence for an HBV X protein–mediated inhibition of PTTG1 ubiquitination and degradation

Hepatology (Baltimore, Md.), 2010-03, Vol.51 (3), p.777-787

2010

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Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis

Nature genetics, 2002-10, Vol.32 (2), p.306-311

2002

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Typical esthetic outcomes using 5 different modalities to treat MIH affected teeth: a case series

Revista de la Facultad de Odontología Universidad de Antioquia, 2023-06, Vol.35 (1)

2023

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UV-induced degradation of securin is mediated by SKP1-CUL1-βTrCP E3 ubiquitin ligase

Journal of cell science, 2008-06, Vol.121 (11), p.1825-1831

2008

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Prognostic Significance of Human Pituitary Tumor-Transforming Gene Immunohistochemical Expression in Differentiated Thyroid Cancer

The journal of clinical endocrinology and metabolism, 2006-04, Vol.91 (4), p.1404-1409

2006

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hpttg, a human homologue of rat pttg, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG

Oncogene, 1998-10, Vol.17 (17), p.2187-2193

1998

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SCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability

Oncotarget, 2014-06, Vol.5 (12), p.4370-4383

2014

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Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase

Nucleic acids research, 2001-03, Vol.29 (6), p.1300-1307

2001

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G1/S phase progression is regulated by PLK1 degradation through the CDK1/βTrCP axis

The FASEB journal, 2017-07, Vol.31 (7), p.2925-2936

2017

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hpttg is over-expressed in pituitary adenomas and other primary epithelial neoplasias

Oncogene, 1999-09, Vol.18 (39), p.5473-5476

1999

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G 1 /S phase progression is regulated by PLK1 degradation through the CDK1/βTrCP axis

The FASEB journal, 2017-07, Vol.31 (7), p.2925-2936

2017

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βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy

Oncotarget, 2014-09, Vol.5 (17), p.7563-7574

2014

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Expression of hpttg proto-oncogene in lymphoid neoplasias

Oncogene, 2002-11, Vol.21 (53), p.8173-8177

2002

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SCFFBXW7α modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability

Oncotarget, 2014-06, Vol.5 (12), p.4370-4383

2014

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Securin Is a Target of the UV Response Pathway in Mammalian Cells

Molecular and Cellular Biology, 2004-04, Vol.24 (7), p.2720-2733

2004

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A single mutation in Securin induces chromosomal instability and enhances cell invasion

European journal of cancer (1990), 2013-01, Vol.49 (2), p.500-510

2013

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p53 and FBXW7: Sometimes Two Guardians Are Worse than One

Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer

Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells

Prostate cancer cell response to paclitaxel is affected by abnormally expressed securin PTTG1

Taste Discrimination after Separate Pre-Exposure and Test Sessions

Protein Phosphatase 2A Stabilizes Human Securin, Whose Phosphorylated Forms Are Degraded via the SCF Ubiquitin Ligase

Both p62/SQSTM1-HDAC6-dependent autophagy and the aggresome pathway mediate CDK1 degradation in human breast cancer

Cisplatin-induced cell death increases the degradation of the MRE11-RAD50-NBS1 complex through the autophagy/lysosomal pathway

SCF(FBXW7)‐mediated degradation of p53 promotes cell recovery after UV‐induced DNA damage

Expression of pituitary tumor–transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)‐associated liver diseases: Evidence for an HBV X protein–mediated inhibition of PTTG1 ubiquitination and degradation

Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis

Typical esthetic outcomes using 5 different modalities to treat MIH affected teeth: a case series

UV-induced degradation of securin is mediated by SKP1-CUL1-βTrCP E3 ubiquitin ligase

Prognostic Significance of Human Pituitary Tumor-Transforming Gene Immunohistochemical Expression in Differentiated Thyroid Cancer

hpttg, a human homologue of rat pttg, is overexpressed in hematopoietic neoplasms. Evidence for a transcriptional activation function of hPTTG

SCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability

Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase

G1/S phase progression is regulated by PLK1 degradation through the CDK1/βTrCP axis

hpttg is over-expressed in pituitary adenomas and other primary epithelial neoplasias

G 1 /S phase progression is regulated by PLK1 degradation through the CDK1/βTrCP axis

βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy

Expression of hpttg proto-oncogene in lymphoid neoplasias

SCFFBXW7α modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability

Securin Is a Target of the UV Response Pathway in Mammalian Cells

A single mutation in Securin induces chromosomal instability and enhances cell invasion

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