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Planar cell polarity pathway in kidney development, function and disease

Nature reviews. Nephrology, 2021-06, Vol.17 (6), p.369-385

2021

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Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes

American journal of physiology. Renal physiology, 2011-02, Vol.300 (2), p.F549-F560

2011

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Intrinsic tumor necrosis factor-α pathway is activated in a subset of patients with focal segmental glomerulosclerosis

PloS one, 2019-05, Vol.14 (5), p.e0216426

2019

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Wilms' tumor gene 1: lessons from the interface between kidney development and cancer

American journal of physiology. Renal physiology, 2024-01, Vol.326 (1), p.F3-F19

2024

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Identification of a novel variant of the ciliopathic gene FUZZY associated with craniosynostosis

European journal of human genetics : EJHG, 2022-03, Vol.30 (3), p.282-290

2022

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Differential role of planar cell polarity gene Vangl2 in embryonic and adult mammalian kidneys

PloS one, 2020-03, Vol.15 (3), p.e0230586-e0230586

2020

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Primary cilia and actin regulatory pathways in renal ciliopathies

Frontiers in Nephrology (Online), 2024-01, Vol.3

2024

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Genetic interaction between members of the Vangl family causes neural tube defects in mice

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (9), p.3449-3454

2008

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Independent Mutations in Mouse Vangl2 That Cause Neural Tube Defects in Looptail Mice Impair Interaction with Members of the Dishevelled Family

The Journal of biological chemistry, 2004-12, Vol.279 (50), p.52703-52713

2004

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An Expanding Role of Vangl Proteins in Embryonic Development

Current Topics in Developmental Biology, 2012, Vol.101, p.237-261

2012

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Loss of Planar Cell Polarity Effector Fuzzy Causes Renal Hypoplasia by Disrupting Several Signaling Pathways

Journal of developmental biology, 2021-12, Vol.10 (1), p.1

2021

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Defining the Interaction Network of the CPLANE Complex Reveals Cilia and Actin Regulatory Components: FR-PO627

Journal of the American Society of Nephrology, 2024-10, Vol.35 (10S)

2024

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Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit

Canadian journal of kidney health and disease, 2022-01, Vol.9, p.20543581221144824-20543581221144824

2022

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The CPLANE Protein Fuzzy Regulates Primary Ciliogenesis Through Actin Remodeling: FR-PO582

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11S), p.564-564

2023

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Planar Cell Polarity Effector Fuzzy in Actin Regulation and Ciliogenesis: FR-PO292

Journal of the American Society of Nephrology, 2022-11, Vol.33 (11S), p.405-405

2022

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PAX2 Activates WNT4 Expression during Mammalian Kidney Development

The Journal of biological chemistry, 2006-05, Vol.281 (18), p.12705-12712

2006

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Can Peer Review Be Kinder? Supportive Peer Review: A Re-Commitment to Kindness and a Call to Action

Canadian journal of kidney health and disease, 2022, Vol.9, p.20543581221080327-20543581221080327

2022

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Hes6 Promotes Cortical Neurogenesis and Inhibits Hes1 Transcription Repression Activity by Multiple Mechanisms

Molecular and Cellular Biology, 2003-10, Vol.23 (19), p.6922-6935

2003

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Plasma from a case of recurrent idiopathic FSGS perturbs non-muscle myosin IIA (MYH9 protein) in human podocytes

Pediatric nephrology (Berlin, West), 2011-07, Vol.26 (7), p.1071-1081

2011

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Recurrent Focal Segmental Glomerulosclerosis: A Discrete Clinical Entity

International Journal of Nephrology, 2012-01, Vol.2012 (2012), p.112-118

2012

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The Wilms’ Tumor Suppressor Gene (wt1) Product Regulates Dax-1 Gene Expression during Gonadal Differentiation

Molecular and Cellular Biology, 1999-03, Vol.19 (3), p.2289-2299

1999

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From podocyte biology to novel cures for glomerular disease

Kidney international, 2019-10, Vol.96 (4), p.850-861

2019

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Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: Effect of the Lp mutation

Gene Expression Patterns, 2007-01, Vol.7 (3), p.346-354

2007

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The CPLANE protein Fuzzy regulates ciliogenesis by suppressing actin polymerization at the base of the primary cilium via p190A RhoGAP

Development (Cambridge), 2024-03, Vol.151 (6)

2024

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Ureteric bud apoptosis and renal hypoplasia in transgenic PAX2-Bax fetal mice mimics the renal-coloboma syndrome

Journal of the American Society of Nephrology, 2003-11, Vol.14 (11), p.2767-2774

2003

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Planar cell polarity pathway in kidney development, function and disease

Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes

Intrinsic tumor necrosis factor-α pathway is activated in a subset of patients with focal segmental glomerulosclerosis

Wilms' tumor gene 1: lessons from the interface between kidney development and cancer

Identification of a novel variant of the ciliopathic gene FUZZY associated with craniosynostosis

Differential role of planar cell polarity gene Vangl2 in embryonic and adult mammalian kidneys

Primary cilia and actin regulatory pathways in renal ciliopathies

Genetic interaction between members of the Vangl family causes neural tube defects in mice

Independent Mutations in Mouse Vangl2 That Cause Neural Tube Defects in Looptail Mice Impair Interaction with Members of the Dishevelled Family

An Expanding Role of Vangl Proteins in Embryonic Development

Loss of Planar Cell Polarity Effector Fuzzy Causes Renal Hypoplasia by Disrupting Several Signaling Pathways

Defining the Interaction Network of the CPLANE Complex Reveals Cilia and Actin Regulatory Components: FR-PO627

Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit

The CPLANE Protein Fuzzy Regulates Primary Ciliogenesis Through Actin Remodeling: FR-PO582

Planar Cell Polarity Effector Fuzzy in Actin Regulation and Ciliogenesis: FR-PO292

PAX2 Activates WNT4 Expression during Mammalian Kidney Development

Can Peer Review Be Kinder? Supportive Peer Review: A Re-Commitment to Kindness and a Call to Action

Hes6 Promotes Cortical Neurogenesis and Inhibits Hes1 Transcription Repression Activity by Multiple Mechanisms

Plasma from a case of recurrent idiopathic FSGS perturbs non-muscle myosin IIA (MYH9 protein) in human podocytes

Recurrent Focal Segmental Glomerulosclerosis: A Discrete Clinical Entity

The Wilms’ Tumor Suppressor Gene (wt1) Product Regulates Dax-1 Gene Expression during Gonadal Differentiation

From podocyte biology to novel cures for glomerular disease

Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: Effect of the Lp mutation

The CPLANE protein Fuzzy regulates ciliogenesis by suppressing actin polymerization at the base of the primary cilium via p190A RhoGAP

Ureteric bud apoptosis and renal hypoplasia in transgenic PAX2-Bax fetal mice mimics the renal-coloboma syndrome

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