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Integrated care in a small island community

International journal of integrated care, 2019-08, Vol.19 (4), p.76

2019

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Antifibrotic effects of a tissue inhibitor of metalloproteinase‐1 antibody on established liver fibrosis in rats

Hepatology (Baltimore, Md.), 2004-11, Vol.40 (5), p.1106-1115

2004

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IL-4 receptor α polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist

Journal of allergy and clinical immunology, 2010-10, Vol.126 (4), p.875-878

2010

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Preferential Binding of Staphylococcus aureus to Skin Sites of Th2-Mediated Inflammation in a Murine Model

Journal of investigative dermatology, 2001-05, Vol.116 (5), p.658-663

2001

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Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice

American journal of respiratory and critical care medicine, 2001-03, Vol.163 (3), p.721-730

2001

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Migration and accumulation of eosinophils toward regional lymph nodes after airway allergen challenge

Journal of allergy and clinical immunology, 2004-10, Vol.114 (4), p.820-825

2004

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The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5

American journal of respiratory and critical care medicine, 1999-10, Vol.160 (4), p.1283-1291

1999

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Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection

Science translational medicine, 2022-02, Vol.14 (633), p.eabl8282

2022

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Alternating Arenavirus Vector Immunization Generates Robust Polyfunctional Genotype Cross-Reactive Hepatitis B Virus–Specific CD8 T-Cell Responses and High Anti–Hepatitis B Surface Antigen Titers

The Journal of infectious diseases, 2024-04, Vol.229 (4), p.1077-1087

2024

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Discovery of GS-7682, a Novel 4′-Cyano-Modified C‑Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys

Journal of medicinal chemistry, 2024-08, Vol.67 (15), p.12945-12968

2024

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Timing of administration of anti-VLA-4 differentiates airway hyperresponsiveness in the central and peripheral airways in mice

American journal of respiratory and critical care medicine, 2000-09, Vol.162 (3), p.1132-1139

2000

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Discovery of an Atropisomeric PI3Kβ Selective Inhibitor through Optimization of the Hinge Binding Motif

ACS medicinal chemistry letters, 2020-06, Vol.11 (6), p.1236-1243

2020

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Anti‐inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor

British journal of pharmacology, 1994-12, Vol.113 (4), p.1423-1431

1994

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The effect of isoenzyme‐selective PDE inhibitors on methacholine‐induced contraction of guinea‐pig and rat ileum

British journal of pharmacology, 1996-08, Vol.118 (8), p.2131-2139

1996

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The late, but not early, asthmatic response is dependent on IL-5 and correlates with eosinophil infiltration

The Journal of clinical investigation, 1999-08, Vol.104 (3), p.301-308

1999

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Possible role of cyclic AMP phosphodiesterases in the actions of ibudilast on eosinophil thromboxane generation and airways smooth muscle tone

British journal of pharmacology, 1994-04, Vol.111 (4), p.1081-1088

1994

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Treatment of Experimental Asthma by Long-Term Gene Therapy Directed against IL-4 and IL-13

Molecular therapy, 2003-02, Vol.7 (2), p.155-162

2003

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The need for standardization in exercise challenge testing for exercise-induced asthma/bronchoconstriction

Journal of allergy and clinical immunology, 2010-10, Vol.126 (4), p.878-880.e6

2010

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IL-4 receptor a polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist

Journal of allergy and clinical immunology, 2010-10, Vol.126 (4), p.875-878

2010

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IL4RA Polymorphisms are Predictors of a Pharmacogenetic Response to a Novel IL4/IL13 Antagonist

Journal of allergy and clinical immunology, 2010-10, Vol.126 (4), p.875-878

2010

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Local treatment with IL-12 is an effective inhibitor of airway hyperresponsiveness and lung eosinophilia after airway challenge in sensitized mice

Journal of allergy and clinical immunology, 1998-07, Vol.102 (1), p.86-93

1998

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Adoptive transfer of T cells induces airway hyperresponsiveness independently of airway eosinophilia but in a signal transducer and activator of transcription 6-dependent manner

Journal of allergy and clinical immunology, 2002-05, Vol.109 (5), p.810-816

2002

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Fas deficiency delays the resolution of airway hyperresponsiveness after allergen sensitization and challenge

Journal of allergy and clinical immunology, 2001-10, Vol.108 (4), p.547-556

2001

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Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing β‐adrenoceptor subtypes

British journal of pharmacology, 1993-01, Vol.108 (1), p.57-61

1993

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Yesterdays

Self and society (London, England), 1989-01, Vol.17 (1), p.36-36

Tomkinson, Adrian

1989

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Integrated care in a small island community

Antifibrotic effects of a tissue inhibitor of metalloproteinase‐1 antibody on established liver fibrosis in rats

IL-4 receptor α polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist

Preferential Binding of Staphylococcus aureus to Skin Sites of Th2-Mediated Inflammation in a Murine Model

Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice

Migration and accumulation of eosinophils toward regional lymph nodes after airway allergen challenge

The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5

Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection

Alternating Arenavirus Vector Immunization Generates Robust Polyfunctional Genotype Cross-Reactive Hepatitis B Virus–Specific CD8 T-Cell Responses and High Anti–Hepatitis B Surface Antigen Titers

Discovery of GS-7682, a Novel 4′-Cyano-Modified C‑Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys

Timing of administration of anti-VLA-4 differentiates airway hyperresponsiveness in the central and peripheral airways in mice

Discovery of an Atropisomeric PI3Kβ Selective Inhibitor through Optimization of the Hinge Binding Motif

Anti‐inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor

The effect of isoenzyme‐selective PDE inhibitors on methacholine‐induced contraction of guinea‐pig and rat ileum

The late, but not early, asthmatic response is dependent on IL-5 and correlates with eosinophil infiltration

Possible role of cyclic AMP phosphodiesterases in the actions of ibudilast on eosinophil thromboxane generation and airways smooth muscle tone

Treatment of Experimental Asthma by Long-Term Gene Therapy Directed against IL-4 and IL-13

The need for standardization in exercise challenge testing for exercise-induced asthma/bronchoconstriction

IL-4 receptor a polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist

IL4RA Polymorphisms are Predictors of a Pharmacogenetic Response to a Novel IL4/IL13 Antagonist

Local treatment with IL-12 is an effective inhibitor of airway hyperresponsiveness and lung eosinophilia after airway challenge in sensitized mice

Adoptive transfer of T cells induces airway hyperresponsiveness independently of airway eosinophilia but in a signal transducer and activator of transcription 6-dependent manner

Fas deficiency delays the resolution of airway hyperresponsiveness after allergen sensitization and challenge

Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing β‐adrenoceptor subtypes

Yesterdays

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