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Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001

The Journal of pharmacology and experimental therapeutics, 1999-05, Vol.289 (2), p.926

1999

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Binding characteristics of [formula omitted]DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors

European journal of pharmacology, 1999-04, Vol.371 (2), p.197-204

1999

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Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106

Life sciences (1973), 1999-03, Vol.64 (16), p.1455-1464

1999

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Synthesis and structure–activity relationships of 5-phenylthiophenecarboxylic acid derivatives as antirheumatic agents

Bioorganic & medicinal chemistry, 2003-11, Vol.11 (22), p.4729-4742

2003

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A Practical Procedure for the Synthesis of Esonarimod, (R,S)-2-Acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic Acid, an Antirheumatic Agent (Part 1)

Chemical and Pharmaceutical Bulletin, 2002, Vol.50(10), pp.1407-1412

2002

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Inhibition of Gastric H+,K+-ATPase by Flavonoids: A Structure-Activity Study

Journal of enzyme inhibition, 1999, Vol.14 (2), p.151-166

1999

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In vitro pharmacological profile of nonpeptide CRF1 receptor antagonists, CRA1000 and CRA1001

European journal of pharmacology, 1999-04, Vol.371 (2-3), p.205-211

1999

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Regulation of NMDA-induced [3H] dopamine release from rat hippocampal slices through sigma-1 binding sites

Neurochemistry international, 1998-07, Vol.33 (1), p.29-34

1998

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Synthesis of Dihydrothiophene Derivatives as Metabolites of Esonarimod

Heterocycles, 2002-10, Vol.57 (10), p.1907

2002

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A selective dopamine D4 receptor antagonist, NRA0160: a preclinical neuropharmacological profile

Life sciences (1973), 1999-10, Vol.65 (20), p.2109-2125

1999

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ACAT inhibitor HL-004 accelerates the regression of hypercholesterolemia in stroke-prone spontaneously hypertensive rats (SHRSP): stimulation of bile acid production by HL-004

Atherosclerosis, 1997-08, Vol.133 (1), p.97-104

1997

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Up-regulation of low density lipoprotein receptor by a novel isobenzofranone derivative, MD-700

Atherosclerosis, 1999-10, Vol.146 (2), p.281-290

1999

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Improvement in cholesterol metabolism in mice given chronic treatment of taurine and fed a high-fat diet

Life sciences (1973), 1999, Vol.64 (1), p.83-91

1999

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Preparation and Antirheumatic Activity of Optically Active 2-Acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic Acid (KE-298)

Chemical and Pharmaceutical Bulletin, 1996/03/15, Vol.44(3), pp.602-604

1996

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Microbial oxidation of KE-298 metabolites by Rhizopus sp. and Rhodococcus sp. strains

Bioscience, biotechnology, and biochemistry, 1998-01, Vol.62 (6), p.1048-1054

1998

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Identification of Metabolites of KE-298, a New Antirheumatic Drug, and Its Physiological Properties in Rats

Biological and Pharmaceutical Bulletin, 1996/03/15, Vol.19(3), pp.424-429

1996

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The atypical antipsychotic profile of NRA0045, a novel dopamine D 4 and 5‐hydroxytryptamine 2A receptor antagonist, in rats

British journal of pharmacology, 2009-02, Vol.121 (3), p.515-525

2009

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The atypical antipsychotic profile of NRA0045, a novel dopamine D4 and 5‐hydroxytryptamine2A receptor antagonist, in rats

British journal of pharmacology, 1997-05, Vol.121 (3), p.515-525

1997

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Studies on Antirheumatic Agents : 3-Benzoylpropionic Acid Derivatives

Chemical and Pharmaceutical Bulletin, 1988/06/25, Vol.36(6), pp.2050-2060

1988

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Structure-Activity Studies of 3-Benzoylpropionic Acid Derivatives Suppressing Adjuvant Arthritis

Chemical and Pharmaceutical Bulletin, 1992/03/25, Vol.40(3), pp.774-777

1992

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Synthesis and SAR of 1-Alkyl-2-phenylethylamine Derivatives Designed from N,N-Dipropyl-4-methoxy-3-(2-phenylethoxy)phenylethylamine To Discover σ1 Ligands

Journal of medicinal chemistry, 1999-09, Vol.42 (19), p.3965-3970

1999

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Design, synthesis and structure-affinity relationships of 4-methylidenepiperidine and 4-aryl-1,2,3,6-tetrahydropyridine derivatives as corticotropin-releasing factor1 receptor antagonists

Bioorganic & medicinal chemistry, 2000-05, Vol.8 (5), p.1183-1193

2000

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Synthesis and antirheumatic activity of the metabolites of esonarimod

Bioorganic & medicinal chemistry, 2002-08, Vol.10 (8), p.2713-2721

2002

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A selective dopamine D 4 receptor antagonist, NRA0160: A preclinical neuropharmacological profile

Life sciences (1973), 1999-10, Vol.65 (20), p.2109-2125

1999

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One-Step Preparation of D-Penicillamine from Benzylpenicillin

Chemical and Pharmaceutical Bulletin, 1989/06/25, Vol.37(6), pp.1609-1611

1989

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Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001

Binding characteristics of [formula omitted]DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors

Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106

Synthesis and structure–activity relationships of 5-phenylthiophenecarboxylic acid derivatives as antirheumatic agents

A Practical Procedure for the Synthesis of Esonarimod, (R,S)-2-Acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic Acid, an Antirheumatic Agent (Part 1)

Inhibition of Gastric H+,K+-ATPase by Flavonoids: A Structure-Activity Study

In vitro pharmacological profile of nonpeptide CRF1 receptor antagonists, CRA1000 and CRA1001

Regulation of NMDA-induced [3H] dopamine release from rat hippocampal slices through sigma-1 binding sites

Synthesis of Dihydrothiophene Derivatives as Metabolites of Esonarimod

A selective dopamine D4 receptor antagonist, NRA0160: a preclinical neuropharmacological profile

ACAT inhibitor HL-004 accelerates the regression of hypercholesterolemia in stroke-prone spontaneously hypertensive rats (SHRSP): stimulation of bile acid production by HL-004

Up-regulation of low density lipoprotein receptor by a novel isobenzofranone derivative, MD-700

Improvement in cholesterol metabolism in mice given chronic treatment of taurine and fed a high-fat diet

Preparation and Antirheumatic Activity of Optically Active 2-Acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic Acid (KE-298)

Microbial oxidation of KE-298 metabolites by Rhizopus sp. and Rhodococcus sp. strains

Identification of Metabolites of KE-298, a New Antirheumatic Drug, and Its Physiological Properties in Rats

The atypical antipsychotic profile of NRA0045, a novel dopamine D 4 and 5‐hydroxytryptamine 2A receptor antagonist, in rats

The atypical antipsychotic profile of NRA0045, a novel dopamine D4 and 5‐hydroxytryptamine2A receptor antagonist, in rats

Studies on Antirheumatic Agents : 3-Benzoylpropionic Acid Derivatives

Structure-Activity Studies of 3-Benzoylpropionic Acid Derivatives Suppressing Adjuvant Arthritis

Synthesis and SAR of 1-Alkyl-2-phenylethylamine Derivatives Designed from N,N-Dipropyl-4-methoxy-3-(2-phenylethoxy)phenylethylamine To Discover σ1 Ligands

Design, synthesis and structure-affinity relationships of 4-methylidenepiperidine and 4-aryl-1,2,3,6-tetrahydropyridine derivatives as corticotropin-releasing factor1 receptor antagonists

Synthesis and antirheumatic activity of the metabolites of esonarimod

A selective dopamine D 4 receptor antagonist, NRA0160: A preclinical neuropharmacological profile

One-Step Preparation of D-Penicillamine from Benzylpenicillin

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