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2-Iminopiperidine and Other 2-Iminoazaheterocycles as Potent Inhibitors of Human Nitric Oxide Synthase Isoforms

Journal of medicinal chemistry, 1996-02, Vol.39 (3), p.669-672

1996

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Substituted 2-Iminopiperidines as Inhibitors of Human Nitric Oxide Synthase Isoforms

Journal of medicinal chemistry, 1998-01, Vol.41 (1), p.96-101

1998

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Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase

European journal of pharmacology, 1995-01, Vol.273 (1), p.15-24

1995

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2-Iminohomopiperidinium Salts as Selective Inhibitors of Inducible Nitric Oxide Synthase (iNOS)

Journal of medicinal chemistry, 1998-04, Vol.41 (9), p.1361-1366

1998

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SC-49992, a mimetic of the peptide arginine-glycine-aspartic acid-phenylalanine that blocks platelet aggregation, enhances recombinant tissue plasminogen activator-induced thrombolysis and prevents reocclusion in a canine model of coronary artery thrombosis

The Journal of pharmacology and experimental therapeutics, 1993-12, Vol.267 (3), p.1191

1993

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Antiplatelet and antithrombotic effects of platelet glycoprotein IIb/IIIa (GPIIb/IIIa) inhibition by arginine-glycine-aspartic acid-serine (RGDS) and arginine-glycine-aspartic acid (RGD) (O-me)Y (SC-46749)

The Journal of pharmacology and experimental therapeutics, 1991-03, Vol.256 (3), p.876

1991

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In vitro and in vivo effects of a peptide mimetic (SC-47643) of RGD as an antiplatelet and antithrombotic agent

Thrombosis research, 1991-06, Vol.62 (5), p.567-578

1991

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Potent in Vitro and in Vivo Inhibitors of Platelet Aggregation Based Upon the Arg-Gly-Asp Sequence of Fibrinogen. (Aminobenzamidino)succinyl (ABAS) Series of Orally Active Fibrinogen Receptor Antagonists

Journal of medicinal chemistry, 1995-06, Vol.38 (13), p.2378-2394

1995

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SC-49992-A potent and specific inhibitor of platelet aggregation

Thrombosis research, 1994-06, Vol.74 (5), p.523-535

1994

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Specific receptors for atriopeptin III in rabbit lung

Biochemical and biophysical research communications, 1986-10, Vol.140 (1), p.302-307

1986

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Inhibitors of human nitric oxide synthase isoforms with the carbamidine moiety as a common structural element

Bioorganic & medicinal chemistry, 1996-09, Vol.4 (9), p.1559-1564

1996

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Differential structure-activity relationships of atrial peptides as natriuretics and renal vasodilators in the dog

Biochemical and biophysical research communications, 1985-04, Vol.128 (1), p.325-330

1985

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Multiple peptide synthesis using a single support (MPS3)

International Journal of Peptide and Protein Research, 1990-02, Vol.35 (2), p.141-146

1990

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Design of orally active, non-peptide fibrinogen receptor antagonists. An evolutionary process from the RGD sequence to novel anti-platelet aggregation agents

Bioorganic & medicinal chemistry, 1994-09, Vol.2 (9), p.881-895

1994

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Aminopeptidase resistant Arg-Gly-Asp analogs are stable in plasma and inhibit platelet aggregation

International Journal of Peptide and Protein Research, 1991-08, Vol.38 (2), p.124-130

1991

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A novel series of orally active antiplatelet agents

Bioorganic & medicinal chemistry, 1995-05, Vol.3 (5), p.539-551

1995

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L-N6-(1-Iminoethyl)lysine: A Selective Inhibitor of Inducible Nitric Oxide Synthase

Journal of medicinal chemistry, 1994-11, Vol.37 (23), p.3886-3888

1994

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Phosphorylation of high- and low-molecular-mass atrial natriuretic peptide analogs by cyclic AMP-dependent protein kinase

FEBS letters, 1987-11, Vol.224 (2), p.325-330

1987

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Biologically active conformations of thymopentin Studies with conformationally restricted analogs

International Journal of Peptide and Protein Research, 1991-03, Vol.37 (3), p.198-209

1991

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4-(2-Chloropropionyl)phenylacetoxy-polyethylene glycol: a new photolabile support for liquid phase peptide synthesis

Tetrahedron letters, 1982, Vol.23 (43), p.4439-4442

1982

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Liquid-phase method for peptide synthesis utilizing photolytic cleavage from a new o-nitrobenzoyl polyethylene glycol support

Biochimica et biophysica acta. Protein structure, 1977-02, Vol.490 (2), p.489-496

1977

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Synthesis of the protected tridecapeptide (56-68) of the VH domain of mouse myeloma immunoglobulin M603 and its reattachment to resin supports

International Journal of Peptide and Protein Research, 1983-08, Vol.22 (2), p.204-213

1983

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SOLID PHASE SYNTHESIS OF THE PROTECTED 27 - 42 HEXADECAPEPTIDE OF THE HEAVY CHAIN FROM MYELOMA IMMUNOGLOBULIN M603 Elimination of Side Reactions Associated with Glycyl-2-oxypropionyl-resin

International Journal of Peptide and Protein Research, 1979-09, Vol.14 (3), p.262-274

1979

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Potent in vitro and in vivo inhibitors of platelet aggregation based upon the Arg-Gly-Asp sequence of fibrinogen. (Aminobenzamidino)succinyl (ABAS) series of orally activ fibrinogen receptor antagonists

Journal of medicinal chemistry, 1995, Vol.38 (13), p.2378-2394

1995

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ChemInform Abstract: SYNTHESIS OF A NEW PHOTOLABILE SUPPORT. 4‐(2‐CHLOROPROPIONYL)PHENYLACETAMIDOMETHYL‐RESIN AND ITS APPLICATION IN SOLID‐PHASE PEPTIDE SYNTHESIS

Chemischer Informationsdienst, 1983-07, Vol.14 (28)

1983

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2-Iminopiperidine and Other 2-Iminoazaheterocycles as Potent Inhibitors of Human Nitric Oxide Synthase Isoforms

Substituted 2-Iminopiperidines as Inhibitors of Human Nitric Oxide Synthase Isoforms

Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase

2-Iminohomopiperidinium Salts as Selective Inhibitors of Inducible Nitric Oxide Synthase (iNOS)

SC-49992, a mimetic of the peptide arginine-glycine-aspartic acid-phenylalanine that blocks platelet aggregation, enhances recombinant tissue plasminogen activator-induced thrombolysis and prevents reocclusion in a canine model of coronary artery thrombosis

Antiplatelet and antithrombotic effects of platelet glycoprotein IIb/IIIa (GPIIb/IIIa) inhibition by arginine-glycine-aspartic acid-serine (RGDS) and arginine-glycine-aspartic acid (RGD) (O-me)Y (SC-46749)

In vitro and in vivo effects of a peptide mimetic (SC-47643) of RGD as an antiplatelet and antithrombotic agent

Potent in Vitro and in Vivo Inhibitors of Platelet Aggregation Based Upon the Arg-Gly-Asp Sequence of Fibrinogen. (Aminobenzamidino)succinyl (ABAS) Series of Orally Active Fibrinogen Receptor Antagonists

SC-49992-A potent and specific inhibitor of platelet aggregation

Specific receptors for atriopeptin III in rabbit lung

Inhibitors of human nitric oxide synthase isoforms with the carbamidine moiety as a common structural element

Differential structure-activity relationships of atrial peptides as natriuretics and renal vasodilators in the dog

Multiple peptide synthesis using a single support (MPS3)

Design of orally active, non-peptide fibrinogen receptor antagonists. An evolutionary process from the RGD sequence to novel anti-platelet aggregation agents

Aminopeptidase resistant Arg-Gly-Asp analogs are stable in plasma and inhibit platelet aggregation

A novel series of orally active antiplatelet agents

L-N6-(1-Iminoethyl)lysine: A Selective Inhibitor of Inducible Nitric Oxide Synthase

Phosphorylation of high- and low-molecular-mass atrial natriuretic peptide analogs by cyclic AMP-dependent protein kinase

Biologically active conformations of thymopentin Studies with conformationally restricted analogs

4-(2-Chloropropionyl)phenylacetoxy-polyethylene glycol: a new photolabile support for liquid phase peptide synthesis

Liquid-phase method for peptide synthesis utilizing photolytic cleavage from a new o-nitrobenzoyl polyethylene glycol support

Synthesis of the protected tridecapeptide (56-68) of the VH domain of mouse myeloma immunoglobulin M603 and its reattachment to resin supports

SOLID PHASE SYNTHESIS OF THE PROTECTED 27 - 42 HEXADECAPEPTIDE OF THE HEAVY CHAIN FROM MYELOMA IMMUNOGLOBULIN M603 Elimination of Side Reactions Associated with Glycyl-2-oxypropionyl-resin

Potent in vitro and in vivo inhibitors of platelet aggregation based upon the Arg-Gly-Asp sequence of fibrinogen. (Aminobenzamidino)succinyl (ABAS) series of orally activ fibrinogen receptor antagonists

ChemInform Abstract: SYNTHESIS OF A NEW PHOTOLABILE SUPPORT. 4‐(2‐CHLOROPROPIONYL)PHENYLACETAMIDOMETHYL‐RESIN AND ITS APPLICATION IN SOLID‐PHASE PEPTIDE SYNTHESIS

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