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Isoflucypram: Combining in vivo and NAMs data in a weight of evidence approach to demonstrate the human non-relevance of the mode of action leading to the subtle thyroid effects observed in the rat

Regulatory toxicology and pharmacology, 2022-06, Vol.131, p.105154-105154, Article 105154

2022

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Isoflucypram: A new fungicide with no thyroid related endocrine disrupting properties and an overall favorable mammalian safety profile

Toxicology letters, 2021-09, Vol.350, p.S246-S246

Tinwell, H.

2021

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Gene regulation by morpholines and piperidines in the cardiac embryonic stem cell test

Toxicology and applied pharmacology, 2021-12, Vol.433, p.115781, Article 115781

2021

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Evaluating H295R steroidogenesis assay data for robust interpretation

Regulatory toxicology and pharmacology, 2023-09, Vol.143, p.105461-105461, Article 105461

2023

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The screening of everyday life chemicals in validated assays targeting the pituitary–gonadal axis

Regulatory toxicology and pharmacology, 2013-07, Vol.66 (2), p.184-196

2013

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Liver tumor formation in female rat induced by fluopyram is mediated by CAR/PXR nuclear receptor activation

Regulatory toxicology and pharmacology, 2014-12, Vol.70 (3), p.648-658

2014

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Genome-wide expression screening in the cardiac embryonic stem cell test shows additional differentiation routes that are regulated by morpholines and piperidines

Current research in toxicology, 2022-01, Vol.3, p.100086-100086, Article 100086

2022

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Molecular neural crest cell markers enable discrimination of organophosphates in the murine cardiac embryonic stem cell test

Toxicology reports, 2021-01, Vol.8, p.1513-1520

2021

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Uterotrophic Activity of Bisphenol A in the Immature Rat

Environmental health perspectives, 1998-11, Vol.106 (11), p.719-720

1998

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Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors

Regulatory toxicology and pharmacology, 2014-12, Vol.70 (3), p.673-680

2014

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Lack of Effects for Low Dose Levels of Bisphenol A and Diethylstilbestrol on the Prostate Gland of CF1 Mice Exposed in Utero

Regulatory toxicology and pharmacology, 1999-10, Vol.30 (2), p.156-166

1999

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Low dose evaluation of the antiandrogen flutamide following a Mode of Action approach

Toxicology and applied pharmacology, 2015-12, Vol.289 (3), p.515-524

2015

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Normal Sexual Development of Two Strains of Rat Exposed in Utero to Low Doses of Bisphenol A

Toxicological sciences, 2002-08, Vol.68 (2), p.339-348

2002

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In vitro skin sensitization test methods: Applicability to plant protection products

Toxicology letters, 2021-09, Vol.350, p.S88-S88

2021

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Metribuzin-induced non-adverse liver changes result in rodent-specific non-adverse thyroid effects via Uridine 5'-diphospho-glucuronosyltransferase (UDPGT, UGT) modulation

Toxicology letters, 2021-09, Vol.350, p.S226-S226

2021

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Natural Variability and the Influence of Concurrent Control Values on the Detection and Interpretation of Low-Dose or Weak Endocrine Toxicities

Environmental health perspectives, 2004-06, Vol.112 (8), p.847-853

2004

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A novel method for measuring aromatase activity in tissue samples by determining estradiol concentrations

Journal of applied toxicology, 2011-07, Vol.31 (5), p.446-454

2011

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The Effect on Sperm Production in Adult Sprague-Dawley Rats Exposed by Gavage to Bisphenol A between Postnatal Days 91–97

Toxicological sciences, 2003-07, Vol.74 (1), p.129-138

2003

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A microfluidic thyroid-liver platform to evaluate species-specific dysregulations of the thyroid hormone axis

Toxicology letters, 2021-09, Vol.350, p.S116-S117

2021

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Correlation between Protein Accumulation Profiles and Conventional Toxicological Findings Using a Model Antiandrogenic Compound, Flutamide

Toxicological sciences, 2007-05, Vol.97 (1), p.81-93

2007

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A microfluidic two-organ chip to investigate species specific differences of thyroid-liver crosstalk in human and rats

Toxicology letters, 2021-09, Vol.350, p.S45-S45

2021

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Transcriptomic and morphological study of the influence of all-trans retinoic acid’s duration exposure on the zebrafish developmental mechanisms

Toxicology letters, 2021-09, Vol.350, p.S144-S144

2021

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Effect of rodent diets on the sexual development of the rat

Toxicological sciences, 2001-05, Vol.61 (1), p.115-127

2001

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Thalidomide is not a human mutagen

BMJ (Online), 2002-11, Vol.325 (7374), p.1245

International edition, 2002

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Estradiol-Type Activity of Coumestrol in Mature and Immature Ovariectomized Rat Uterotrophic Assays

Environmental health perspectives, 2000-07, Vol.108 (7), p.631-634

2000

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Isoflucypram: Combining in vivo and NAMs data in a weight of evidence approach to demonstrate the human non-relevance of the mode of action leading to the subtle thyroid effects observed in the rat

Isoflucypram: A new fungicide with no thyroid related endocrine disrupting properties and an overall favorable mammalian safety profile

Gene regulation by morpholines and piperidines in the cardiac embryonic stem cell test

Evaluating H295R steroidogenesis assay data for robust interpretation

The screening of everyday life chemicals in validated assays targeting the pituitary–gonadal axis

Liver tumor formation in female rat induced by fluopyram is mediated by CAR/PXR nuclear receptor activation

Genome-wide expression screening in the cardiac embryonic stem cell test shows additional differentiation routes that are regulated by morpholines and piperidines

Molecular neural crest cell markers enable discrimination of organophosphates in the murine cardiac embryonic stem cell test

Uterotrophic Activity of Bisphenol A in the Immature Rat

Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors

Lack of Effects for Low Dose Levels of Bisphenol A and Diethylstilbestrol on the Prostate Gland of CF1 Mice Exposed in Utero

Low dose evaluation of the antiandrogen flutamide following a Mode of Action approach

Normal Sexual Development of Two Strains of Rat Exposed in Utero to Low Doses of Bisphenol A

In vitro skin sensitization test methods: Applicability to plant protection products

Metribuzin-induced non-adverse liver changes result in rodent-specific non-adverse thyroid effects via Uridine 5'-diphospho-glucuronosyltransferase (UDPGT, UGT) modulation

Natural Variability and the Influence of Concurrent Control Values on the Detection and Interpretation of Low-Dose or Weak Endocrine Toxicities

A novel method for measuring aromatase activity in tissue samples by determining estradiol concentrations

The Effect on Sperm Production in Adult Sprague-Dawley Rats Exposed by Gavage to Bisphenol A between Postnatal Days 91–97

A microfluidic thyroid-liver platform to evaluate species-specific dysregulations of the thyroid hormone axis

Correlation between Protein Accumulation Profiles and Conventional Toxicological Findings Using a Model Antiandrogenic Compound, Flutamide

A microfluidic two-organ chip to investigate species specific differences of thyroid-liver crosstalk in human and rats

Transcriptomic and morphological study of the influence of all-trans retinoic acid’s duration exposure on the zebrafish developmental mechanisms

Effect of rodent diets on the sexual development of the rat

Thalidomide is not a human mutagen

Estradiol-Type Activity of Coumestrol in Mature and Immature Ovariectomized Rat Uterotrophic Assays

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