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FGF21: An Emerging Therapeutic Target for Non-Alcoholic Steatohepatitis and Related Metabolic Diseases

Frontiers in endocrinology (Lausanne), 2020-12, Vol.11, p.601290

2020

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Efruxifermin in non-alcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a trial

Nature medicine, 2021-07, Vol.27 (7), p.1262-1271

2021

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Three months of high-fructose feeding fails to induce excessive weight gain or leptin resistance in mice

PloS one, 2014-09, Vol.9 (9), p.e107206-e107206

2014

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Global transcriptional regulation of innate immunity by ATF-7 in C. elegans

PLoS genetics, 2019-02, Vol.15 (2), p.e1007830-e1007830

2019

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De-differentiation confers multidrug resistance via noncanonical PERK-Nrf2 signaling

PLoS biology, 2014-09, Vol.12 (9), p.e1001945-e1001945

2014

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AKR-001, an Fc-FGF21 Analog, Showed Sustained Pharmacodynamic Effects on Insulin Sensitivity and Lipid Metabolism in Type 2 Diabetes Patients

Cell reports. Medicine, 2020-07, Vol.1 (4), p.100057-100057, Article 100057

2020

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A randomized trial comparing balloon kyphoplasty and vertebroplasty for vertebral compression fractures due to osteoporosis

American journal of neuroradiology : AJNR, 2014-12, Vol.35 (12), p.2227-2236

2014

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Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (25), p.10165-10170

2013

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Effect of a Centralized Clinical Pharmacy Anticoagulation Service on the Outcomes of Anticoagulation Therapy

Chest, 2005-05, Vol.127 (5), p.1515-1522

2005

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DFT study of nano zinc/copper voltaic cells

Journal of molecular modeling, 2018-04, Vol.24 (4), p.103-17, Article 103

2018

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Activation of β-catenin/TCF targets following loss of the tumor suppressor SNF5

Oncogene, 2014-02, Vol.33 (7), p.933-938

2014

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Design of Muon Campus full flow purifier for varying operational conditions and horizontal shipping

IOP conference series. Materials Science and Engineering, 2024-05, Vol.1301 (1), p.12121

2024

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Stabilization of Cardiac Ryanodine Receptor Prevents Intracellular Calcium Leak and Arrhythmias

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (20), p.7906-7910

2006

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An Integrative Model of Moral Deliberation

Tillman, J. Jeffrey

1, 2016

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A randomized trial comparing 2 techniques of balloon kyphoplasty and curette use for obtaining vertebral body height restoration and angular-deformity correction in vertebral compression fractures due to osteoporosis

American journal of neuroradiology : AJNR, 2013-03, Vol.34 (3), p.666-675

2013

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Impact of Treatments on Diabetic Control and Gastrointestinal Symptoms After Total Pancreatectomy

Pancreas, 2017-10, Vol.46 (9), p.1188-1195

2017

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Efruxifermin, a long‐acting Fc‐fusion FGF21 analogue, reduces body weight gain but does not increase sympathetic tone or urine volume in Sprague Dawley rats

British journal of pharmacology, 2022-04, Vol.179 (7), p.1384-1394

2022

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DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells

Cancer research (Chicago, Ill.), 2007-05, Vol.67 (10), p.4630-4637

2007

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The impact of different health dimensions on overall quality of life related to kyphoplasty and non-surgical management

Osteoporosis international, 2013-07, Vol.24 (7), p.1991-1999

2013

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Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors

Cell cycle (Georgetown, Tex.), 2012-05, Vol.11 (10), p.1956-1965

2012

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Insect pheromones—an overview of biosynthesis and endocrine regulation

Insect Biochemistry and Molecular Biology, 1999-06, Vol.29 (6), p.481-514

1999

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119-LB: Increased Adiponectin following Efruxifermin Treatment Is Associated with Improvements in Dyslipidemia, Glucose Metabolism, and Liver Health in a 16-Week, Randomized, Placebo-Controlled NASH Trial

Diabetes (New York, N.Y.), 2021-06, Vol.70 (Supplement_1)

2021

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Safety and Efficacy of Efruxifermin in Combination With a GLP-1 Receptor Agonist in Patients With NASH/MASH and Type 2 Diabetes in a Randomized Phase 2 Study

Clinical gastroenterology and hepatology, 2024-03

2024

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Noncompetitive immunoassay optimized for pharmacokinetic assessments of biologically active efruxifermin

Journal of pharmaceutical and biomedical analysis, 2023-08, Vol.232, p.115402-115402, Article 115402

2023

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Does It Mix?

The Science teacher (National Science Teachers Association), 2016-03, Vol.83 (3), p.41

2016

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FGF21: An Emerging Therapeutic Target for Non-Alcoholic Steatohepatitis and Related Metabolic Diseases

Efruxifermin in non-alcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a trial

Three months of high-fructose feeding fails to induce excessive weight gain or leptin resistance in mice

Global transcriptional regulation of innate immunity by ATF-7 in C. elegans

De-differentiation confers multidrug resistance via noncanonical PERK-Nrf2 signaling

AKR-001, an Fc-FGF21 Analog, Showed Sustained Pharmacodynamic Effects on Insulin Sensitivity and Lipid Metabolism in Type 2 Diabetes Patients

A randomized trial comparing balloon kyphoplasty and vertebroplasty for vertebral compression fractures due to osteoporosis

Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters

Effect of a Centralized Clinical Pharmacy Anticoagulation Service on the Outcomes of Anticoagulation Therapy

DFT study of nano zinc/copper voltaic cells

Activation of β-catenin/TCF targets following loss of the tumor suppressor SNF5

Design of Muon Campus full flow purifier for varying operational conditions and horizontal shipping

Stabilization of Cardiac Ryanodine Receptor Prevents Intracellular Calcium Leak and Arrhythmias

An Integrative Model of Moral Deliberation

A randomized trial comparing 2 techniques of balloon kyphoplasty and curette use for obtaining vertebral body height restoration and angular-deformity correction in vertebral compression fractures due to osteoporosis

Impact of Treatments on Diabetic Control and Gastrointestinal Symptoms After Total Pancreatectomy

Efruxifermin, a long‐acting Fc‐fusion FGF21 analogue, reduces body weight gain but does not increase sympathetic tone or urine volume in Sprague Dawley rats

DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells

The impact of different health dimensions on overall quality of life related to kyphoplasty and non-surgical management

Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors

Insect pheromones—an overview of biosynthesis and endocrine regulation

119-LB: Increased Adiponectin following Efruxifermin Treatment Is Associated with Improvements in Dyslipidemia, Glucose Metabolism, and Liver Health in a 16-Week, Randomized, Placebo-Controlled NASH Trial

Safety and Efficacy of Efruxifermin in Combination With a GLP-1 Receptor Agonist in Patients With NASH/MASH and Type 2 Diabetes in a Randomized Phase 2 Study

Noncompetitive immunoassay optimized for pharmacokinetic assessments of biologically active efruxifermin

Does It Mix?

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