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Fatty Acid Synthase Inhibition in Human Breast Cancer Cells Leads to Malonyl-CoA-Induced Inhibition of Fatty Acid Oxidation and Cytotoxicity

Biochemical and biophysical research communications, 2001-07, Vol.285 (2), p.217-223

2001

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C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism

The Journal of biological chemistry, 2004-01, Vol.279 (5), p.3817-3827

2004

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Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop New Inhibitors of Type I Fatty Acid Synthase

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.946-961

2005

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Endotoxemia in burn patients: levels of circulating endotoxins are related to burn size

Surgery, 1987-11, Vol.102 (5), p.808

1987

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Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts

Cancer research (Chicago, Ill.), 2000-01, Vol.60 (2), p.213-218

2000

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C75 Increases Peripheral Energy Utilization and Fatty Acid Oxidation in Diet-Induced Obesity

Proceedings of the National Academy of Sciences - PNAS, 2002-07, Vol.99 (14), p.9498-9502

2002

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Chronic C75 treatment of diet-induced obese mice increases fat oxidation and reduces food intake to reduce adipose mass

American journal of physiology: endocrinology and metabolism, 2004-07, Vol.287 (1), p.E97-E104

2004

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The Pathogenicity of Spontaneously-Occurring Thyroglobulin-Reactive T Lymphocytes from BB/WOR Rats

Autoimmunity (Chur, Switzerland), 1996, Vol.23 (1), p.35-44

1996

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Characteristics of Shigella sonnei infection of volunteers: signs, symptoms, immune responses, changes in selected cytokines and acute-phase substances

The American journal of tropical medicine and hygiene, 1995-07, Vol.53 (1), p.47

1995

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C75 Alters Central and Peripheral Gene Expression to Reduce Food Intake and Increase Energy Expenditure

Endocrinology (Philadelphia), 2005-01, Vol.146 (1), p.486-493

2005

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Thyroglobulin-reactive T lymphocytes in thyroiditis-prone BB/Wor rats

Journal of endocrinological investigation, 1995-01, Vol.18 (1), p.45-49

1995

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Second-generation inhibitors of fatty acid synthase for lung cancer treatment

Journal of clinical oncology, 2007-06, Vol.25 (18_suppl), p.18185-18185

2007

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Depressed natural killer cell function in thermally injured adults: successful in vivo and in vitro immunomodulation and the role of endotoxin

Clinical and experimental immunology, 1988, Vol.71 (1), p.120-125

1988

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Effect of immunoglobulin G therapy on serum antibody titers to cytomegalovirus in Burn patients

The American journal of surgery, 1988-02, Vol.155 (2), p.294-296

1988

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Lightning injury: physics, pathophysiology and clinical features

Irish medical journal, 1986-05, Vol.79 (5), p.120-122

1986

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Reversal of Postburn Immunosuppression with Low-dose Polymyxin B

The Journal of trauma, 1986-11, Vol.26 (11), p.995-998

1986

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Thyroglobulin-reactive T lymphocytes in thryoiditis-prone BB/Wor rats

Journal of endocrinological investigation, 1995, Vol.18 (1), p.45-49

1995

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Autoantibody formation in burn patients after inhibition of suppressor T cell activity with polymyxin B

Journal of burn care & rehabilitation, 1989-05, Vol.10 (3), p.213

1989

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Electric- and lightning-induced cardiac arrest reversed by cardiopulmonary resuscitation

JAMA : the journal of the American Medical Association, 1986-04, Vol.255 (16), p.2157

1986

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Endotoxemia in burn patients: Levels of circulating endotoxins are related to burn site

Plastic and reconstructive surgery (1963), 1988-11, Vol.82 (5), p.933

1988

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Prophylactic intravenous immunoglobulin replacement in high-risk burn patients

Journal of burn care & rehabilitation, 1987-09, Vol.8 (5), p.376

1987

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Systemic stimulation of fatty acid oxidation reduces food intake in diet‐induced obese mice

The FASEB journal, 2006-03, Vol.20 (5), p.A830-A830

2006

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WITHDRAWN: “Intracerebroventricular administration of either C89b, a stimulator of carnitinepalmitoyl-transferase-1 (CPT-1s), or cerulenin, an inhibitor of fatty acid synthase (FASi), reduces food intake and body weight in mice”

Appetite, 2006-05

2006

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Fatty Acid Synthase Inhibition in Human Breast Cancer Cells Leads to Malonyl-CoA-Induced Inhibition of Fatty Acid Oxidation and Cytotoxicity

C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism

Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop New Inhibitors of Type I Fatty Acid Synthase

Endotoxemia in burn patients: levels of circulating endotoxins are related to burn size

Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts

C75 Increases Peripheral Energy Utilization and Fatty Acid Oxidation in Diet-Induced Obesity

Chronic C75 treatment of diet-induced obese mice increases fat oxidation and reduces food intake to reduce adipose mass

The Pathogenicity of Spontaneously-Occurring Thyroglobulin-Reactive T Lymphocytes from BB/WOR Rats

Characteristics of Shigella sonnei infection of volunteers: signs, symptoms, immune responses, changes in selected cytokines and acute-phase substances

C75 Alters Central and Peripheral Gene Expression to Reduce Food Intake and Increase Energy Expenditure

Thyroglobulin-reactive T lymphocytes in thyroiditis-prone BB/Wor rats

Second-generation inhibitors of fatty acid synthase for lung cancer treatment

Depressed natural killer cell function in thermally injured adults: successful in vivo and in vitro immunomodulation and the role of endotoxin

Effect of immunoglobulin G therapy on serum antibody titers to cytomegalovirus in Burn patients

Lightning injury: physics, pathophysiology and clinical features

Reversal of Postburn Immunosuppression with Low-dose Polymyxin B

Thyroglobulin-reactive T lymphocytes in thryoiditis-prone BB/Wor rats

Autoantibody formation in burn patients after inhibition of suppressor T cell activity with polymyxin B

Electric- and lightning-induced cardiac arrest reversed by cardiopulmonary resuscitation

Endotoxemia in burn patients: Levels of circulating endotoxins are related to burn site

Prophylactic intravenous immunoglobulin replacement in high-risk burn patients

Systemic stimulation of fatty acid oxidation reduces food intake in diet‐induced obese mice

WITHDRAWN: “Intracerebroventricular administration of either C89b, a stimulator of carnitinepalmitoyl-transferase-1 (CPT-1s), or cerulenin, an inhibitor of fatty acid synthase (FASi), reduces food intake and body weight in mice”

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