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An Artificial Heme Enzyme for Cyclopropanation Reactions

Angewandte Chemie International Edition, 2018-06, Vol.57 (26), p.7785-7789

International ed. in English, 2018

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Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid

Angewandte Chemie International Edition, 2019-02, Vol.58 (7), p.2083-2087

International ed. in English, 2019

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Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium

The FEBS journal, 2016-11, Vol.283 (22), p.4128-4148

2016

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Regio- and stereoselective steroid hydroxylation by CYP109A2 from Bacillus megaterium explored by X-ray crystallography and computational modeling

The FEBS journal, 2023-10, Vol.290 (20), p.5016-5035

2023

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Engineered C–N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners

Angewandte Chemie International Edition, 2020-01, Vol.59 (1), p.429-435

International ed. in English, 2020

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Subunit and chlorophyll organization of the plant photosystem II supercomplex

Nature plants, 2017-06, Vol.3 (7), p.17080, Article 17080

2017

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Using Mutability Landscapes To Guide Enzyme Thermostabilization

Chembiochem : a European journal of chemical biology, 2021-01, Vol.22 (1), p.170-175

2021

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Biochemical and structural characterization of CYP109A2, a vitamin D3 25‐hydroxylase from Bacillus megaterium

The FEBS journal, 2017-11, Vol.284 (22), p.3881-3894

2017

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Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors

Science (American Association for the Advancement of Science), 1998-07, Vol.281 (5376), p.533-538

1998

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Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition

The EMBO journal, 2009-01, Vol.28 (2), p.156-166

2009

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Cofactor Binding Dynamics Influence the Catalytic Activity and Selectivity of an Artificial Metalloenzyme

ACS catalysis, 2020-10, Vol.10 (20), p.11783-11790

2020

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Robust ω‑Transaminases by Computational Stabilization of the Subunit Interface

ACS catalysis, 2020-03, Vol.10 (5), p.2915-2928

2020

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On the Mechanism of Peptidoglycan Binding and Cleavage by the endo-Specific Lytic Transglycosylase MltE from Escherichia coli

Biochemistry (Easton), 2012-11, Vol.51 (45), p.9164-9177

2012

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Engineering methylaspartate ammonia lyase for the asymmetric synthesis of unnatural amino acids

Nature chemistry, 2012-06, Vol.4 (6), p.478-484

2012

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Aspartase/Fumarase Superfamily: A Common Catalytic Strategy Involving General Base-Catalyzed Formation of a Highly Stabilized aci -Carboxylate Intermediate

Biochemistry (Easton), 2012-05, Vol.51 (21), p.4237-4243

2012

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Functional Characterization of Mutations in the Myosin Vb Gene Associated With Microvillus Inclusion Disease

Journal of pediatric gastroenterology and nutrition, 2011-03, Vol.52 (3), p.307-313

2011

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Structural Basis for the Catalytic Mechanism of Aspartate Ammonia Lyase

Biochemistry (Easton), 2011-07, Vol.50 (27), p.6053-6062

2011

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Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases

Nature communications, 2016-03, Vol.7 (1), p.10911-10911, Article 10911

2016

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Crystal structures of two transcriptional regulators from Bacillus cereus define the conserved structural features of a PadR subfamily

PloS one, 2012-11, Vol.7 (11), p.e48015-e48015

2012

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The structural basis for peptide selection by the transport receptor OppA

The EMBO journal, 2009-05, Vol.28 (9), p.1332-1340

2009

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Enantioselective Synthesis of Pharmaceutically Active γ‑Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions

ACS catalysis, 2019-02, Vol.9 (2), p.1503-1513

2019

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Ecological risks of imidacloprid to aquatic species in the Netherlands: Measured and estimated concentrations compared to species sensitivity distributions

Chemosphere (Oxford), 2020-09, Vol.254, p.126604-126604, Article 126604

2020

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Biocatalytic enantioselective hydroaminations enabling synthesis of N -arylalkyl-substituted L-aspartic acids

Organic & biomolecular chemistry, 2021-07, Vol.19 (29), p.6407-6411

2021

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Computational Redesign of an ω‑Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines

ACS catalysis, 2021-09, Vol.11 (17), p.10733-10747

2021

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Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA

Journal of Bacteriology, 2011-08, Vol.193 (16), p.4254-4256

2011

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An Artificial Heme Enzyme for Cyclopropanation Reactions

Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid

Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium

Regio- and stereoselective steroid hydroxylation by CYP109A2 from Bacillus megaterium explored by X-ray crystallography and computational modeling

Engineered C–N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners

Subunit and chlorophyll organization of the plant photosystem II supercomplex

Using Mutability Landscapes To Guide Enzyme Thermostabilization

Biochemical and structural characterization of CYP109A2, a vitamin D3 25‐hydroxylase from Bacillus megaterium

Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors

Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition

Cofactor Binding Dynamics Influence the Catalytic Activity and Selectivity of an Artificial Metalloenzyme

Robust ω‑Transaminases by Computational Stabilization of the Subunit Interface

On the Mechanism of Peptidoglycan Binding and Cleavage by the endo-Specific Lytic Transglycosylase MltE from Escherichia coli

Engineering methylaspartate ammonia lyase for the asymmetric synthesis of unnatural amino acids

Aspartase/Fumarase Superfamily: A Common Catalytic Strategy Involving General Base-Catalyzed Formation of a Highly Stabilized aci -Carboxylate Intermediate

Functional Characterization of Mutations in the Myosin Vb Gene Associated With Microvillus Inclusion Disease

Structural Basis for the Catalytic Mechanism of Aspartate Ammonia Lyase

Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases

Crystal structures of two transcriptional regulators from Bacillus cereus define the conserved structural features of a PadR subfamily

The structural basis for peptide selection by the transport receptor OppA

Enantioselective Synthesis of Pharmaceutically Active γ‑Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions

Ecological risks of imidacloprid to aquatic species in the Netherlands: Measured and estimated concentrations compared to species sensitivity distributions

Biocatalytic enantioselective hydroaminations enabling synthesis of N -arylalkyl-substituted L-aspartic acids

Computational Redesign of an ω‑Transaminase from Pseudomonas jessenii for Asymmetric Synthesis of Enantiopure Bulky Amines

Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA

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