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Drug metabolism and transport during pregnancy: how does drug disposition change during pregnancy and what are the mechanisms that cause such changes?

Drug metabolism and disposition, 2013-02, Vol.41 (2), p.256-262

2013

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Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport

Kidney international, 2014-03, Vol.85 (3), p.522-528

2014

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Development of a microphysiological model of human kidney proximal tubule function

Kidney international, 2016-09, Vol.90 (3), p.627-637

2016

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Regional proteomic quantification of clinically relevant non-cytochrome P450 enzymes along the human small intestine

Drug metabolism and disposition, 2020-07, Vol.48 (7), p.528-536

2020

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The Utility of Mixed Effects Models in the Evaluation of Complex Genomic Traits In Vitro

Drug metabolism and disposition, 2023-11, Vol.51 (11), p.1455-1462

2023

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Calling Star Alleles With Stargazer in 28 Pharmacogenes With Whole Genome Sequences

Clinical pharmacology and therapeutics, 2019-12, Vol.106 (6), p.1328-1337

2019

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Implementing Precision Medicine: The Ethical Challenges

Trends in pharmacological sciences (Regular ed.), 2017-01, Vol.38 (1), p.8-14

2017

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CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations

The journal of clinical endocrinology and metabolism, 2017-05, Vol.102 (5), p.1440-1446

2017

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Gut instincts: CYP3A4 and intestinal drug metabolism

The Journal of clinical investigation, 2007-11, Vol.117 (11), p.3173-3176

Thummel, Kenneth E

2007

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Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model

Genetics in medicine, 2019-02, Vol.21 (2), p.361-372

2019

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Interplay between vitamin D and the drug metabolizing enzyme CYP3A4

The Journal of steroid biochemistry and molecular biology, 2013-07, Vol.136, p.54-58

2013

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Human Enteroid Monolayers: A Novel, Functionally-Stable Model for Investigating Oral Drug Disposition

Drug metabolism and disposition, 2024-08, p.DMD-AR-2023-001551

2024

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Evaluation of Cytochrome P450‐Mediated Cannabinoid‐Drug Interactions in Healthy Adult Participants

Clinical pharmacology and therapeutics, 2023-09, Vol.114 (3), p.693-703

2023

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Interpreting tacrolimus concentrations during pregnancy and postpartum

Transplantation, 2013-04, Vol.95 (7), p.908-915

2013

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The development of an intestinal microphysiological system to model oral drug disposition

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Vitamin D Metabolism Is Dysregulated in Asthma and Chronic Obstructive Pulmonary Disease

American journal of respiratory and critical care medicine, 2020-08, Vol.202 (3), p.371-382

2020

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CYP3A4 mutation causes vitamin D-dependent rickets type 3

The Journal of clinical investigation, 2018-05, Vol.128 (5), p.1913-1918

2018

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Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism

Drug metabolism and disposition, 2016-03, Vol.44 (3), p.343-351

2016

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Gutsy science: In vitro systems of the human intestine to model oral drug disposition

Pharmacology & therapeutics (Oxford), 2022-02, Vol.230, p.107962-107962, Article 107962

2022

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Translating Kratom-Drug Interactions: From Bedside to Bench and Back

Drug metabolism and disposition, 2023-08, Vol.51 (8), p.923-935

2023

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Renal secretion of hydrochlorothiazide involves organic anion transporter 1/3, organic cation transporter 2, and multidrug and toxin extrusion protein 2-K

American journal of physiology. Renal physiology, 2019-10, Vol.317 (4), p.F805-F814

2019

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Genetic contribution to variable human CYP3A-mediated metabolism

Advanced drug delivery reviews, 2002-11, Vol.54 (10), p.1271-1294

2002

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Genetic factors affecting statin concentrations and subsequent myopathy: a HuGENet systematic review

Genetics in medicine, 2014-11, Vol.16 (11), p.810-819

2014

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Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom

Clinical pharmacology and therapeutics, 2023-06, Vol.113 (6), p.1315-1325

2023

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Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans

Drug metabolism and disposition, 2018-04, Vol.46 (4), p.367-379

2018

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Drug metabolism and transport during pregnancy: how does drug disposition change during pregnancy and what are the mechanisms that cause such changes?

Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport

Development of a microphysiological model of human kidney proximal tubule function

Regional proteomic quantification of clinically relevant non-cytochrome P450 enzymes along the human small intestine

The Utility of Mixed Effects Models in the Evaluation of Complex Genomic Traits In Vitro

Calling Star Alleles With Stargazer in 28 Pharmacogenes With Whole Genome Sequences

Implementing Precision Medicine: The Ethical Challenges

CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations

Gut instincts: CYP3A4 and intestinal drug metabolism

Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model

Interplay between vitamin D and the drug metabolizing enzyme CYP3A4

Human Enteroid Monolayers: A Novel, Functionally-Stable Model for Investigating Oral Drug Disposition

Evaluation of Cytochrome P450‐Mediated Cannabinoid‐Drug Interactions in Healthy Adult Participants

Interpreting tacrolimus concentrations during pregnancy and postpartum

The development of an intestinal microphysiological system to model oral drug disposition

Vitamin D Metabolism Is Dysregulated in Asthma and Chronic Obstructive Pulmonary Disease

CYP3A4 mutation causes vitamin D-dependent rickets type 3

Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism

Gutsy science: In vitro systems of the human intestine to model oral drug disposition

Translating Kratom-Drug Interactions: From Bedside to Bench and Back

Renal secretion of hydrochlorothiazide involves organic anion transporter 1/3, organic cation transporter 2, and multidrug and toxin extrusion protein 2-K

Genetic contribution to variable human CYP3A-mediated metabolism

Genetic factors affecting statin concentrations and subsequent myopathy: a HuGENet systematic review

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom

Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans

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