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Complement activation, regulation, and molecular basis for complement-related diseases

The EMBO journal, 2015-11, Vol.34 (22), p.2735-2757

2015

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Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement

The Journal of immunology (1950), 2017-09, Vol.199 (6), p.2158-2170

2017

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Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (5), p.986-991

2017

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COLLECTINS AND FICOLINS: Humoral Lectins of the Innate Immune Defense

Annual review of immunology, 2003-01, Vol.21 (1), p.547-578

2003

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Disease-Causing Mutations in Genes of the Complement System

American journal of human genetics, 2011-06, Vol.88 (6), p.689-705

2011

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Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults

Scientific reports, 2020-06, Vol.10 (1), p.10561-10561, Article 10561

2020

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Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function

The Journal of immunology (1950), 2012-10, Vol.189 (8), p.3957-3969

2012

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Toward a structure-based comprehension of the lectin pathway of complement

Molecular immunology, 2013-12, Vol.56 (4), p.413-422

2013

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Proteolysis and inflammation of the kidney glomerulus

Cell and tissue research, 2021-08, Vol.385 (2), p.489-500

2021

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Associations between the Complement System and Choroidal Neovascularization in Wet Age-Related Macular Degeneration

International journal of molecular sciences, 2020-12, Vol.21 (24), p.9752

2020

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Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity

Journal of neuroinflammation, 2021-08, Vol.18 (1), p.177-177, Article 177

2021

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The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes

Scientific reports, 2021-04, Vol.11 (1), p.8919-8919, Article 8919

2021

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The C3dg Fragment of Complement Is Superior to Conventional C3 as a Diagnostic Biomarker in Systemic Lupus Erythematosus

Frontiers in immunology, 2018-03, Vol.9, p.581-581

2018

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Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes

International journal of molecular sciences, 2024-07, Vol.25 (13), p.7204

2024

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Antigen footprint governs activation of the B cell receptor

Nature communications, 2023-02, Vol.14 (1), p.976-976, Article 976

2023

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MASP‐2 deficiency does not prevent the progression of diabetic kidney disease in a mouse model of type 1 diabetes

Scandinavian journal of immunology, 2024-04, Vol.99 (4), p.e13348-n/a

2024

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Remote ischemic preconditioning does not influence lectin pathway protein levels in head and neck cancer patients undergoing surgery

PloS one, 2020-04, Vol.15 (4), p.e0230411-e0230411

2020

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Protein–fatty acid complexes: biochemistry, biophysics and function

The FEBS journal, 2013-04, Vol.280 (8), p.1733-1749

2013

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Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

Scientific reports, 2022-09, Vol.12 (1), p.15955-15955, Article 15955

2022

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Abundant human anti-Galα3Gal antibodies display broad pathogen reactivity

Scientific reports, 2020-03, Vol.10 (1), p.4611-4611, Article 4611

2020

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Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity

Frontiers in immunology, 2022-07, Vol.13, p.872536-872536

2022

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Structural basis for activation of the complement system by component C4 cleavage

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (38), p.15425-15430

2012

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Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins

Molecular immunology, 2007-09, Vol.44 (16), p.3875-3888

Thiel, Steffen

2007

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Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

Frontiers in immunology, 2019-08, Vol.10, p.2007-2007

2019

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Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (37), p.13445-13450

2014

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Complement activation, regulation, and molecular basis for complement-related diseases

Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement

Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

COLLECTINS AND FICOLINS: Humoral Lectins of the Innate Immune Defense

Disease-Causing Mutations in Genes of the Complement System

Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults

Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function

Toward a structure-based comprehension of the lectin pathway of complement

Proteolysis and inflammation of the kidney glomerulus

Associations between the Complement System and Choroidal Neovascularization in Wet Age-Related Macular Degeneration

Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity

The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes

The C3dg Fragment of Complement Is Superior to Conventional C3 as a Diagnostic Biomarker in Systemic Lupus Erythematosus

Mannan-Binding Lectin Is Associated with Inflammation and Kidney Damage in a Mouse Model of Type 2 Diabetes

Antigen footprint governs activation of the B cell receptor

MASP‐2 deficiency does not prevent the progression of diabetic kidney disease in a mouse model of type 1 diabetes

Remote ischemic preconditioning does not influence lectin pathway protein levels in head and neck cancer patients undergoing surgery

Protein–fatty acid complexes: biochemistry, biophysics and function

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

Abundant human anti-Galα3Gal antibodies display broad pathogen reactivity

Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity

Structural basis for activation of the complement system by component C4 cleavage

Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes

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