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Cytochrome P450 and flavin-containing monooxygenase families: age-dependent differences in expression and functional activity

Pediatric research, 2018-02, Vol.83 (2), p.527-535

2018

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A Physiologically Based Pharmacokinetic Model for Voriconazole Disposition Predicts Intestinal First-pass Metabolism in Children

Clinical pharmacokinetics, 2014-12, Vol.53 (12), p.1171-1182

2014

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Four cation-selective transporters contribute to apical uptake and accumulation of metformin in Caco-2 cell monolayers

The Journal of pharmacology and experimental therapeutics, 2015-03, Vol.352 (3), p.519-528

2015

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Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Molecular pharmacology, 2013-08, Vol.84 (2), p.182-189

2013

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Mechanisms underlying saturable intestinal absorption of metformin

Drug metabolism and disposition, 2008-08, Vol.36 (8), p.1650-1658

2008

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Role of basolateral efflux transporter MRP4 in the intestinal absorption of the antiviral drug adefovir dipivoxil

Biochemical pharmacology, 2010-02, Vol.79 (3), p.455-462

2010

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Vectorial Transport of Fexofenadine across Caco-2 Cells: Involvement of Apical Uptake and Basolateral Efflux Transporters

Molecular pharmaceutics, 2011-10, Vol.8 (5), p.1677-1686

2011

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Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Drug metabolism and disposition, 2013-06, Vol.41 (6), p.1179-1186

2013

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Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.484-496

2016

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Transport of dicationic drugs pentamidine and furamidine by human organic cation transporters

Drug metabolism and disposition, 2009-02, Vol.37 (2), p.424-430

2009

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Physiologically Based Pharmacokinetic Models for Adults and Children Reveal a Role of Intracellular Tubulin Binding in Vincristine Disposition

CPT: pharmacometrics and systems pharmacology, 2019-10, Vol.8 (10), p.759-768

2019

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Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium

Pharmaceutical research, 2003-08, Vol.20 (8), p.1210-1224

2003

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Direct Activation of Human Phospholipase C by Its Well Known Inhibitor U73122

The Journal of biological chemistry, 2011-04, Vol.286 (14), p.12407-12416

2011

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Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)

The Journal of pharmacology and experimental therapeutics, 2005-12, Vol.315 (3), p.1288-1297

2005

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Role of flavin-containing monooxygenase in oxidative metabolism of voriconazole by human liver microsomes

Drug metabolism and disposition, 2008-06, Vol.36 (6), p.1119-1125

2008

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Efficacious dose of metformin for breast cancer therapy is determined by cation transporter expression in tumours

British journal of pharmacology, 2019-08, Vol.176 (15), p.2724-2735

2019

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Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells

Pharmaceutical research, 2003-08, Vol.20 (8), p.1192-1199

2003

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In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats

Drug metabolism and disposition, 2010-10, Vol.38 (10), p.1848-1856

2010

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High‐throughput screening for stability and inhibitory activity of compounds toward cytochrome P450‐mediated metabolism

Journal of pharmaceutical sciences, 2004-02, Vol.93 (2), p.239-255

2004

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Exploring the role of the pharmacist in global health

Journal of the American Pharmacists Association, 2014-09, Vol.54 (5), p.552-555

2014

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Enhancing paracellular permeability by modulating epithelial tight junctions

Pharmaceutical Science & Technology Today, 2000-10, Vol.3 (10), p.346-358

2000

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Cation‐selective transporters are critical to the AMPK‐mediated antiproliferative effects of metformin in human breast cancer cells

International journal of cancer, 2016-05, Vol.138 (9), p.2281-2292

2016

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Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny

Drug metabolism and disposition, 2016-07, Vol.44 (7), p.975-983

2016

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Determination of the Androgen Receptor Inhibitor Enzalutamide and its Metabolites in Animal Plasma and Brain Homogenates Using LC-MS/MS and its Application to Pharmacokinetic Studies

CHROMATOGRAPHY, 2015/12/20, Vol.36(3), pp.115-122

2015

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P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes

Drug metabolism and disposition, 2001-10, Vol.29 (10), p.1277

2001

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Cytochrome P450 and flavin-containing monooxygenase families: age-dependent differences in expression and functional activity

A Physiologically Based Pharmacokinetic Model for Voriconazole Disposition Predicts Intestinal First-pass Metabolism in Children

Four cation-selective transporters contribute to apical uptake and accumulation of metformin in Caco-2 cell monolayers

Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Mechanisms underlying saturable intestinal absorption of metformin

Role of basolateral efflux transporter MRP4 in the intestinal absorption of the antiviral drug adefovir dipivoxil

Vectorial Transport of Fexofenadine across Caco-2 Cells: Involvement of Apical Uptake and Basolateral Efflux Transporters

Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis

Transport of dicationic drugs pentamidine and furamidine by human organic cation transporters

Physiologically Based Pharmacokinetic Models for Adults and Children Reveal a Role of Intracellular Tubulin Binding in Vincristine Disposition

Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium

Direct Activation of Human Phospholipase C by Its Well Known Inhibitor U73122

Differential substrate and inhibitory activities of ranitidine and famotidine toward human organic cation transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)

Role of flavin-containing monooxygenase in oxidative metabolism of voriconazole by human liver microsomes

Efficacious dose of metformin for breast cancer therapy is determined by cation transporter expression in tumours

Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells

In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats

High‐throughput screening for stability and inhibitory activity of compounds toward cytochrome P450‐mediated metabolism

Exploring the role of the pharmacist in global health

Enhancing paracellular permeability by modulating epithelial tight junctions

Cation‐selective transporters are critical to the AMPK‐mediated antiproliferative effects of metformin in human breast cancer cells

Quantification of Flavin-containing Monooxygenases 1, 3, and 5 in Human Liver Microsomes by UPLC-MRM-Based Targeted Quantitative Proteomics and Its Application to the Study of Ontogeny

Determination of the Androgen Receptor Inhibitor Enzalutamide and its Metabolites in Animal Plasma and Brain Homogenates Using LC-MS/MS and its Application to Pharmacokinetic Studies

P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes

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