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Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase

Biochemical journal, 1993-02, Vol.290 (1), p.41-49

1993

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ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site

Molecular and cellular neuroscience, 2000-11, Vol.16 (5), p.609-619

2000

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Nitric oxide synthases catalyze the activation of redox cycling and bioreductive anticancer agents

Cancer research (Chicago, Ill.), 1999-04, Vol.59 (8), p.1929-1934

1999

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Steady-State Kinetic Characterization of Substrates and Metal-Ion Specificities of the Full-Length and N-Terminally Truncated Recombinant Human Methionine Aminopeptidases (Type 2)

Biochemistry (Easton), 2001-09, Vol.40 (35), p.10645-10654

2001

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Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins

Arteriosclerosis, thrombosis, and vascular biology, 1996-04, Vol.16 (4), p.591

1996

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

Molecular and cellular neuroscience, 1999-12, Vol.14 (6), p.419-427

1999

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Dissection of NADPH-Cytochrome P450 Oxidoreductase into Distinct Functional Domains

Proceedings of the National Academy of Sciences - PNAS, 1994-08, Vol.91 (18), p.8710-8714

1994

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Inhibition of herpes proteases and antiviral activity of 2-substituted thieno[2,3-d]oxazinones

Bioorganic & medicinal chemistry letters, 1999-02, Vol.9 (3), p.443-448

1999

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Lipoprotein-associated phospholipase A(2), platelet-activating factor acetylhydrolase, is expressed by macrophages in human and rabbit atherosclerotic lesions

Arteriosclerosis, thrombosis, and vascular biology, 1999-12, Vol.19 (12), p.2909

1999

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Benzothiopyran-4-one based reversible inhibitors of the human cytomegalovirus (HCMV) protease

Bioorganic & medicinal chemistry letters, 1998-12, Vol.8 (24), p.3677-3682

1998

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Inhibition of human cytomegalovirus protease by enedione derivatives of thieno[2,3-d]oxazinones through a novel dual acylation/alkylation mechanism

Bioorganic & medicinal chemistry letters, 1999-02, Vol.9 (3), p.449-452

1999

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Cloning and Characterization of a Novel Human Dual Flavin Reductase

The Journal of biological chemistry, 2000-01, Vol.275 (2), p.1471-1478

2000

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Napsins: new human aspartic proteinases: Distinction between two closely related genes

FEBS letters, 1998-12, Vol.441 (1), p.43-48

1998

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Identification, Genomic Organization, and mRNA Expression of LACTB, Encoding a Serine β-Lactamase-like Protein with an Amino-terminal Transmembrane Domain

Genomics (San Diego, Calif.), 2001-11, Vol.78 (1-2), p.12-14

2001

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Highly Potent Inhibitors of Methionine Aminopeptidase-2 Based on a 1,2,4-Triazole Pharmacophore

Journal of medicinal chemistry, 2007-08, Vol.50 (16), p.3777-3785

2007

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Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor

Biochemical journal, 1999-03, Vol.338 ( Pt 2) (2), p.479-487

1999

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Mechanism of Inhibition of Cathepsin K by Potent, Selective 1,5-Diacylcarbohydrazides: A New Class of Mechanism-Based Inhibitors of Thiol Proteases

Biochemistry (Easton), 1999-11, Vol.38 (48), p.15893-15902

1999

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2-(alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A2

Bioorganic & medicinal chemistry letters, 2000-02, Vol.10 (4), p.395-398

2000

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Structure-based design of non-peptide, carbohydrazide-based cathepsin K inhibitors

Bioorganic & medicinal chemistry, 1999-04, Vol.7 (4), p.599-605

1999

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Structure-Based Design of Cathepsin K Inhibitors Containing a Benzyloxy-Substituted Benzoyl Peptidomimetic

Journal of medicinal chemistry, 1998-10, Vol.41 (21), p.3923-3927

1998

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The rate of oxygen consumption and superoxide anion formation by stimulated human neutrophils The effect of particle concentration and size

FEBS letters, 1987-05, Vol.216 (1), p.31-34

1987

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Inhibition of cytochrome P450 reductase by the diphenyliodonium cation. Kinetic analysis and covalent modifications

Biochemistry (Easton), 1993-09, Vol.32 (38), p.10209-10215

Tew, David G

1993

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Applications of spin-trapping to biological systems

Biochemical Society transactions, 1985-06, Vol.13 (3), p.600

1985

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Determination of phosphate in nanomolar range by an enzyme-coupling fluorescent method

Analytical biochemistry, 2003-09, Vol.320 (2), p.292-298

2003

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Mechanism of Inhibition of LDL Phospholipase A2 by Monocyclic-β-lactams. Burst Kinetics and the Effect of Stereochemistry

Biochemistry (Easton), 1998-07, Vol.37 (28), p.10087-10093

1998

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Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase

ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site

Nitric oxide synthases catalyze the activation of redox cycling and bioreductive anticancer agents

Steady-State Kinetic Characterization of Substrates and Metal-Ion Specificities of the Full-Length and N-Terminally Truncated Recombinant Human Methionine Aminopeptidases (Type 2)

Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

Dissection of NADPH-Cytochrome P450 Oxidoreductase into Distinct Functional Domains

Inhibition of herpes proteases and antiviral activity of 2-substituted thieno[2,3-d]oxazinones

Lipoprotein-associated phospholipase A(2), platelet-activating factor acetylhydrolase, is expressed by macrophages in human and rabbit atherosclerotic lesions

Benzothiopyran-4-one based reversible inhibitors of the human cytomegalovirus (HCMV) protease

Inhibition of human cytomegalovirus protease by enedione derivatives of thieno[2,3-d]oxazinones through a novel dual acylation/alkylation mechanism

Cloning and Characterization of a Novel Human Dual Flavin Reductase

Napsins: new human aspartic proteinases: Distinction between two closely related genes

Identification, Genomic Organization, and mRNA Expression of LACTB, Encoding a Serine β-Lactamase-like Protein with an Amino-terminal Transmembrane Domain

Highly Potent Inhibitors of Methionine Aminopeptidase-2 Based on a 1,2,4-Triazole Pharmacophore

Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor

Mechanism of Inhibition of Cathepsin K by Potent, Selective 1,5-Diacylcarbohydrazides: A New Class of Mechanism-Based Inhibitors of Thiol Proteases

2-(alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A2

Structure-based design of non-peptide, carbohydrazide-based cathepsin K inhibitors

Structure-Based Design of Cathepsin K Inhibitors Containing a Benzyloxy-Substituted Benzoyl Peptidomimetic

The rate of oxygen consumption and superoxide anion formation by stimulated human neutrophils The effect of particle concentration and size

Inhibition of cytochrome P450 reductase by the diphenyliodonium cation. Kinetic analysis and covalent modifications

Applications of spin-trapping to biological systems

Determination of phosphate in nanomolar range by an enzyme-coupling fluorescent method

Mechanism of Inhibition of LDL Phospholipase A2 by Monocyclic-β-lactams. Burst Kinetics and the Effect of Stereochemistry

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