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Efficacy of the PSD95 inhibitor Tat-NR2B9c in mice requires dose translation between species

Journal of cerebral blood flow and metabolism, 2016-03, Vol.36 (3), p.555-561

2016

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Modulation of NMDAR subunit expression by TRPM2 channels regulates neuronal vulnerability to ischemic cell death

The Journal of neuroscience, 2013-10, Vol.33 (44), p.17264-17277

2013

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Mice and Rats Exhibit Striking Inter-species Differences in Gene Response to Acute Stroke

Cellular and molecular neurobiology, 2022-11, Vol.42 (8), p.2773-2789

2022

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Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

Nature neuroscience, 2009-10, Vol.12 (10), p.1300-1307

2009

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Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

Nature (London), 2012-03, Vol.483 (7388), p.213-217

2012

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Increased phosphorylation and redistribution of NMDA receptors between synaptic lipid rafts and post‐synaptic densities following transient global ischemia in the rat brain

Journal of neurochemistry, 2005-04, Vol.93 (1), p.186-194

2005

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Plasmin-resistant PSD-95 inhibitors resolve effect-modifying drug-drug interactions between alteplase and nerinetide in acute stroke

Science translational medicine, 2021-04, Vol.13 (588)

2021

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Ischemia and status epilepitcus result in enhanced phosphorylation of calcium and calmodulin-stimulated protein kinase II on threonine 253

Brain research, 2008-07, Vol.1218, p.158-165

2008

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A translational paradigm for the preclinical evaluation of the stroke neuroprotectant Tat-NR2B9c in gyrencephalic nonhuman primates

Science translational medicine, 2012-10, Vol.4 (154), p.154ra133

2012

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Altered Interaction Between PSD‐95 and the NMDA Receptor Following Transient Global Ischemia

Journal of neurochemistry, 2000-01, Vol.74 (1), p.169-178

2000

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Abstract 25: Promoting Recovery After Stroke by Manipulating NMDA Receptor-Associated Signalling in the Early Post Stroke Phase

Stroke (1970), 2019-02, Vol.50 (Suppl_1)

2019

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Deep Brain Stimulation Rescues Memory and Synaptic Activity in a Rat Model of Global Ischemia

The Journal of neuroscience, 2019-03, Vol.39 (13), p.2430-2440

2019

Volltextzugriff (PDF)

Transient Ischemia Differentially Increases Tyrosine Phosphorylation of NMDA Receptor Subunits 2A and 2B

Journal of neurochemistry, 1997-09, Vol.69 (3), p.1060-1065

1997

Volltextzugriff (PDF)

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

Nature (London), 2012-03, Vol.483 (7388), p.213

2012

Volltextzugriff (PDF)

Effectiveness of PSD95 Inhibitors in Permanent and Transient Focal Ischemia in the Rat

Stroke (1970), 2008-09, Vol.39 (9), p.2544-2553

2008

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Transient Cerebral Ischemia Increases Tyrosine Phosphorylation of the Synaptic RAS-GTPase Activating Protein, SynGAP

Journal of cerebral blood flow and metabolism, 2001-08, Vol.21 (8), p.955-963

2001

Volltextzugriff (PDF)

Inhibition of protein kinase C reduces ischemia‐induced tyrosine phosphorylation of the N‐methyl‐d‐aspartate receptor

Journal of neurochemistry, 2003-09, Vol.86 (6), p.1441-1449

2003

Volltextzugriff (PDF)

The Effect of Transient Global Ischemia on the Interaction of Src and Fyn with the N-Methyl-d-Aspartate Receptor and Postsynaptic Densities: Possible Involvement of Src Homology 2 Domains

Journal of cerebral blood flow and metabolism, 1999-08, Vol.19 (8), p.880-888

1999

Volltextzugriff (PDF)

Altered Association of Protein Tyrosine Kinases With Postsynaptic Densities After Transient Cerebral Ischemia in the Rat Brain

Journal of cerebral blood flow and metabolism, 2000-03, Vol.20 (3), p.505-512

2000

Volltextzugriff (PDF)

Increased phosphorylation of the NR1 subunit of the NMDA receptor following cerebral ischemia

Journal of neurochemistry, 2001-09, Vol.78 (5), p.1179-1182

2001

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2023

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Animals
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Life Sciences & Biomedicine
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Neurosciences & Neurology
(15)
Neurosciences
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Rats
(13)
Biological And Medical Sciences
(11)
Medical Sciences
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Neurology
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Rats, Wistar
(11)
Vascular Diseases And Vascular Malformations Of The Nervous System
(11)
Ischemia
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Ischemic Attack, Transient - Metabolism
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Disease Models, Animal
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Nmda Receptor
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Phosphorylation
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Receptors, N-Methyl-D-Aspartate - Metabolism
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Tyrosine Phosphorylation
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Efficacy of the PSD95 inhibitor Tat-NR2B9c in mice requires dose translation between species

Modulation of NMDAR subunit expression by TRPM2 channels regulates neuronal vulnerability to ischemic cell death

Mice and Rats Exhibit Striking Inter-species Differences in Gene Response to Acute Stroke

Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

Increased phosphorylation and redistribution of NMDA receptors between synaptic lipid rafts and post‐synaptic densities following transient global ischemia in the rat brain

Plasmin-resistant PSD-95 inhibitors resolve effect-modifying drug-drug interactions between alteplase and nerinetide in acute stroke

Ischemia and status epilepitcus result in enhanced phosphorylation of calcium and calmodulin-stimulated protein kinase II on threonine 253

A translational paradigm for the preclinical evaluation of the stroke neuroprotectant Tat-NR2B9c in gyrencephalic nonhuman primates

Altered Interaction Between PSD‐95 and the NMDA Receptor Following Transient Global Ischemia

Abstract 25: Promoting Recovery After Stroke by Manipulating NMDA Receptor-Associated Signalling in the Early Post Stroke Phase

Deep Brain Stimulation Rescues Memory and Synaptic Activity in a Rat Model of Global Ischemia

Transient Ischemia Differentially Increases Tyrosine Phosphorylation of NMDA Receptor Subunits 2A and 2B

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

Effectiveness of PSD95 Inhibitors in Permanent and Transient Focal Ischemia in the Rat

Transient Cerebral Ischemia Increases Tyrosine Phosphorylation of the Synaptic RAS-GTPase Activating Protein, SynGAP

Inhibition of protein kinase C reduces ischemia‐induced tyrosine phosphorylation of the N‐methyl‐d‐aspartate receptor

The Effect of Transient Global Ischemia on the Interaction of Src and Fyn with the N-Methyl-d-Aspartate Receptor and Postsynaptic Densities: Possible Involvement of Src Homology 2 Domains

Altered Association of Protein Tyrosine Kinases With Postsynaptic Densities After Transient Cerebral Ischemia in the Rat Brain

Increased phosphorylation of the NR1 subunit of the NMDA receptor following cerebral ischemia

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