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Clarifying the absence of evidence regarding human health risks to microplastic particles in drinking-water: High quality robust data wanted

Environment international, 2021-05, Vol.150, p.106141, Article 106141

2021

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Human variability in polymorphic CYP2D6 metabolism: Implications for the risk assessment of chemicals in food and emerging designer drugs

Environment international, 2021-11, Vol.156, p.106760, Article 106760

2021

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S27-02 Human interindividual variability in toxicokinetics

Toxicology letters, 2024-09, Vol.399, p.S47-S48

Testai, E.

2024

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Bayesian meta-analysis of inter-phenotypic differences in human serum paraoxonase-1 activity for chemical risk assessment

Environment international, 2020-05, Vol.138, p.105609, Article 105609

2020

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Human Variability in Carboxylesterases and carboxylesterase-related Uncertainty Factors for Chemical Risk Assessment

Toxicology letters, 2021-10, Vol.350, p.162-170

2021

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Human variability in influx and efflux transporters in relation to uncertainty factors for chemical risk assessment

Food and chemical toxicology, 2020-06, Vol.140, p.111305, Article 111305

2020

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Water quality and human health: A simple monitoring model of toxic cyanobacteria growth in highly variable Mediterranean hot dry environments

Environmental research, 2021-01, Vol.192, p.110291, Article 110291

2021

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The importance of protein binding for the in vitro–in vivo extrapolation (IVIVE)—example of ibuprofen, a highly protein-bound substance

Archives of toxicology, 2017-04, Vol.91 (4), p.1663-1670

2017

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Cyclosporine A kinetics in brain cell cultures and its potential of crossing the blood–brain barrier

Toxicology in vitro, 2015-12, Vol.30 (1), p.166-175

2015

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Safety evaluation of technically unavoidable traces of metals in cosmetics

Toxicology letters, 2015-10, Vol.238 (2), p.S60-S60

2015

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Dose-response relationship: Monotone vs non-monotone curve

Toxicology letters, 2015-10, Vol.238 (2), p.S51-S51

Testai, E.

2015

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Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures

Toxicology in vitro, 2015-12, Vol.30 (1), p.176-184

2015

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Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems

Toxicology in vitro, 2015-12, Vol.30 (1), p.62-78

2015

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Interleukin-1 Gene Polymorphisms and Gastric Cancer Risk in a High-Risk Italian Population

The American journal of gastroenterology, 2005-09, Vol.100 (9), p.1941-1948

2005

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Toxicology investigations with cell culture systems: 20 years after

Toxicology in vitro, 2004-04, Vol.18 (2), p.153-163

2004

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P05-35 Molecular modelling study on CYP2C19 mediated biotransformation of organophosphorothioate pesticides: insights on a possible mutational landscape

Toxicology letters, 2024-09, Vol.399, p.S145-S145

2024

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Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54

Alternatives to laboratory animals, 2006-02, Vol.34 (1), p.49-84

2006

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Organophosphorothionate pesticides inhibit the bioactivation of imipramine by human hepatic cytochrome P450s

Toxicology and applied pharmacology, 2005-06, Vol.205 (3), p.237-246

2005

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P03-11 Assessing kinetic properties in food and feed: tebuconazole case study

Toxicology letters, 2024-09, Vol.399, p.S126-S126

2024

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EFSA'S risk assessment of bisphenol A in food

Toxicology letters, 2011-08, Vol.205, p.S52-S52

2011

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Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches

Toxicology in vitro, 2013-08, Vol.27 (5), p.1570-1577

2013

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Hierarchical Bayesian meta-analysis of human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for human risk assessment

Toxicology letters, 2018-10, Vol.295, p.S249-S249

2018

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The relevance of xenobiotic metabolism in the interindividual susceptibility to chemicals

Folia histochemica et cytobiologica, 2001, Vol.39 Suppl 2, p.48

Testai, E

2001

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The drug-metabolizing enzymatic system and the experimental tools used for in vitro toxicology for metabolic studies

Cell biology and toxicology, 2001-01, Vol.17 (4-5), p.271-285

TESTAI, Emanuela

2001

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Clarifying the absence of evidence regarding human health risks to microplastic particles in drinking-water: High quality robust data wanted

Human variability in polymorphic CYP2D6 metabolism: Implications for the risk assessment of chemicals in food and emerging designer drugs

S27-02 Human interindividual variability in toxicokinetics

Bayesian meta-analysis of inter-phenotypic differences in human serum paraoxonase-1 activity for chemical risk assessment

Human Variability in Carboxylesterases and carboxylesterase-related Uncertainty Factors for Chemical Risk Assessment

Human variability in influx and efflux transporters in relation to uncertainty factors for chemical risk assessment

Water quality and human health: A simple monitoring model of toxic cyanobacteria growth in highly variable Mediterranean hot dry environments

The importance of protein binding for the in vitro–in vivo extrapolation (IVIVE)—example of ibuprofen, a highly protein-bound substance

Cyclosporine A kinetics in brain cell cultures and its potential of crossing the blood–brain barrier

Safety evaluation of technically unavoidable traces of metals in cosmetics

Dose-response relationship: Monotone vs non-monotone curve

Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures

Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems

Interleukin-1 Gene Polymorphisms and Gastric Cancer Risk in a High-Risk Italian Population

Toxicology investigations with cell culture systems: 20 years after

P05-35 Molecular modelling study on CYP2C19 mediated biotransformation of organophosphorothioate pesticides: insights on a possible mutational landscape

Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54

Organophosphorothionate pesticides inhibit the bioactivation of imipramine by human hepatic cytochrome P450s

P03-11 Assessing kinetic properties in food and feed: tebuconazole case study

EFSA'S risk assessment of bisphenol A in food

Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches

Hierarchical Bayesian meta-analysis of human variability in CYP3A4 metabolism and CYP3A4-related uncertainty factors for human risk assessment

The relevance of xenobiotic metabolism in the interindividual susceptibility to chemicals

The drug-metabolizing enzymatic system and the experimental tools used for in vitro toxicology for metabolic studies

Guidance Document on Scientific criteria for grouping chemicals into assessment groups for human risk assessment of combined exposure to multiple chemicals

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