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A comparison of pharmacokinetics between humans and monkeys

Drug metabolism and disposition, 2010-02, Vol.38 (2), p.308

2010

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Utility of hepatocytes in predicting drug metabolism: comparison of hepatic intrinsic clearance in rats and humans in vivo and in vitro

Drug metabolism and disposition, 2003-05, Vol.31 (5), p.580

2003

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Quantitative prediction of intestinal metabolism in humans from a simplified intestinal availability model and empirical scaling factor

Drug metabolism and disposition, 2010-07, Vol.38 (7), p.1230

2010

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Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans

Drug metabolism and disposition, 2001-10, Vol.29 (10), p.1316

2001

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Quantitative Prediction of Intestinal Glucuronidation of Drugs in Rats Using In Vitro Metabolic Clearance Data

DRUG METABOLISM AND PHARMACOKINETICS, 2012, Vol.27 (2), p.171-180

2012

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Novel Carbapenem Antibiotics for Parenteral and Oral Applications: In Vitro and In Vivo Activities of 2-Aryl Carbapenems and Their Pharmacokinetics in Laboratory Animals

Antimicrobial Agents and Chemotherapy, 2013-02, Vol.57 (2), p.697-707

2013

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Correlation of Intrinsic in vitro and in vivo Clearance for Drugs Metabolized by Hepatic UDP-glucuronosyltransferases in Rats

DRUG METABOLISM AND PHARMACOKINETICS, 2011-01, Vol.26 (5), p.465-473

2011

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Quantitative prediction of human intestinal glucuronidation effects on intestinal availability of UDP-glucuronosyltransferase substrates using in vitro data

Drug metabolism and disposition, 2012-09, Vol.40 (9), p.1771

2012

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Method for predicting human intestinal first-pass metabolism of UGT substrate compounds

Xenobiotica, 2012-10, Vol.42 (10), p.980-988

2012

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Cloning and Functional Expression of a Human Liver Organic Cation Transporter

Molecular pharmacology, 1997-06, Vol.51 (6), p.913-921

1997

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Utility of Microtiter Plate Assays for Human Cytochrome P450 Inhibition Studies in Drug Discovery: Application of Simple Method for Detecting Quasi-irreversible and Irreversible Inhibitors

DRUG METABOLISM AND PHARMACOKINETICS, 2004, Vol.19 (1), p.55-61

2004

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Exploratory population pharmacokinetics (e-PPK) analysis for predicting human PK using exploratory ADME data during early drug discovery research

European journal of drug metabolism and pharmacokinetics, 2009-04, Vol.34 (2), p.117-128

2009

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Prediction of human metabolism of FK3453 by aldehyde oxidase using chimeric mice transplanted with human or rat hepatocytes

Drug metabolism and disposition, 2012-01, Vol.40 (1), p.76

2012

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Molecular cloning and functional expression of a rabbit renal organic cation transporter

Biochimica et biophysica acta, 1998-02, Vol.1369 (1), p.1-6

1998

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Comparison of intestinal metabolism of CYP3A substrates between rats and humans: application of portal-systemic concentration difference method

Xenobiotica, 2014-06, Vol.44 (6), p.511-521

2014

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Strategy for structural elucidation of drugs and drug metabolites using (MS)n fragmentation in an electrospray ion trap

Journal of mass spectrometry., 2003-08, Vol.38 (8), p.793-808

2003

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Real-time Microdialysis for aβ Inhibition And Pk/pd Analysis in A Nonhuman Primate Model: In Vivo Efficacy of a Bace-1 Inhibitor

Alzheimer's & dementia, 2010-07, Vol.6 (4), p.e73-e73

2010

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P3‐298: In vivo efficacy of BACE‐1 inhibitor CTS21166 (ASP1702) in rat CNS compartments

Alzheimer's & dementia, 2009-07, Vol.5 (4S_Part_14), p.P430-P431

2009

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In vivo efficacy of BACE-1 inhibitor CTS21166 (ASP1702) in rat CNS compartments

Alzheimer's & dementia, 2009-07, Vol.5 (4), p.P430-P431

2009

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Reaction Mechanism of 21S Dynein ATPase from Sea Urchin Sperm. I. Kinetic Properties in the Steady State

Journal of biochemistry (Tokyo), 1983, Vol.93 (6), p.1567-1574

1983

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Reaction Mechanism of 21S Dynein ATPase from Sea Urchin Sperm. I. Kinetic Properties in the Steady State1

Journal of biochemistry (Tokyo), 1983-01, Vol.93 (6), p.1567-1574

1983

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Reaction Mechanism of 21S Dynein ATPase from Sea Urchin Sperm. II. Formation of Reaction Intermediates

Journal of biochemistry (Tokyo), 1983, Vol.93 (6), p.1575-1581

1983

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Effects of FK037 on the Aldehyde Dehydrogenase and the Drug Metabolizing Enzyme System in Rats

Drug Metabolism and Pharmacokinetics, 1995, Vol.10(3), pp.359-368

1995

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Urinary Metabolites of Nilvadipine in Man

Drug Metabolism and Pharmacokinetics, 1987, Vol.2(6), pp.649-655

1987

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PREDICTION OF IN VIVO HUMAN HEPATIC CLEARANCE IN DRUG DISCOVERY

Drug Metabolism and Pharmacokinetics, 2000, Vol.15(supplement), pp.120-121

2000

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A comparison of pharmacokinetics between humans and monkeys

Utility of hepatocytes in predicting drug metabolism: comparison of hepatic intrinsic clearance in rats and humans in vivo and in vitro

Quantitative prediction of intestinal metabolism in humans from a simplified intestinal availability model and empirical scaling factor

Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans

Quantitative Prediction of Intestinal Glucuronidation of Drugs in Rats Using In Vitro Metabolic Clearance Data

Novel Carbapenem Antibiotics for Parenteral and Oral Applications: In Vitro and In Vivo Activities of 2-Aryl Carbapenems and Their Pharmacokinetics in Laboratory Animals

Correlation of Intrinsic in vitro and in vivo Clearance for Drugs Metabolized by Hepatic UDP-glucuronosyltransferases in Rats

Quantitative prediction of human intestinal glucuronidation effects on intestinal availability of UDP-glucuronosyltransferase substrates using in vitro data

Method for predicting human intestinal first-pass metabolism of UGT substrate compounds

Cloning and Functional Expression of a Human Liver Organic Cation Transporter

Utility of Microtiter Plate Assays for Human Cytochrome P450 Inhibition Studies in Drug Discovery: Application of Simple Method for Detecting Quasi-irreversible and Irreversible Inhibitors

Exploratory population pharmacokinetics (e-PPK) analysis for predicting human PK using exploratory ADME data during early drug discovery research

Prediction of human metabolism of FK3453 by aldehyde oxidase using chimeric mice transplanted with human or rat hepatocytes

Molecular cloning and functional expression of a rabbit renal organic cation transporter

Comparison of intestinal metabolism of CYP3A substrates between rats and humans: application of portal-systemic concentration difference method

Strategy for structural elucidation of drugs and drug metabolites using (MS)n fragmentation in an electrospray ion trap

Real-time Microdialysis for aβ Inhibition And Pk/pd Analysis in A Nonhuman Primate Model: In Vivo Efficacy of a Bace-1 Inhibitor

P3‐298: In vivo efficacy of BACE‐1 inhibitor CTS21166 (ASP1702) in rat CNS compartments

In vivo efficacy of BACE-1 inhibitor CTS21166 (ASP1702) in rat CNS compartments

Reaction Mechanism of 21S Dynein ATPase from Sea Urchin Sperm. I. Kinetic Properties in the Steady State

Reaction Mechanism of 21S Dynein ATPase from Sea Urchin Sperm. I. Kinetic Properties in the Steady State1

Reaction Mechanism of 21S Dynein ATPase from Sea Urchin Sperm. II. Formation of Reaction Intermediates

Effects of FK037 on the Aldehyde Dehydrogenase and the Drug Metabolizing Enzyme System in Rats

Urinary Metabolites of Nilvadipine in Man

PREDICTION OF IN VIVO HUMAN HEPATIC CLEARANCE IN DRUG DISCOVERY

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