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mTOR and autophagy: A dynamic relationship governed by nutrients and energy

Seminars in cell & developmental biology, 2014-12, Vol.36, p.121-129

2014

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Possible Targets for Nonimmunosuppressive Therapy of Graves' Orbitopathy

The journal of clinical endocrinology and metabolism, 2014-07, Vol.99 (7), p.E1183-E1190

2014

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Reversal of Pathological Features of Graves' Orbitopathy by Activation of Forkhead Transcription Factors, FOXOs

The journal of clinical endocrinology and metabolism, 2016-01, Vol.101 (1), p.114-122

2016

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Absence of the Birt-Hogg-Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

Oncogene, 2011-03, Vol.30 (10), p.1159-1173

2011

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mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3

Oncogene, 2015-04, Vol.34 (17), p.2239-2250

2015

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Mammalian target of rapamycin complex 1: Signalling inputs, substrates and feedback mechanisms

Cellular signalling, 2009-06, Vol.21 (6), p.827-835

2009

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mTOR, translational control and human disease

Seminars in cell & developmental biology, 2005-02, Vol.16 (1), p.29-37

2005

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DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling

Oncogene, 2000-06, Vol.19 (26), p.3021-3031

2000

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Staurosporine inhibits phosphorylation of translational regulators linked to mTOR

Cell death and differentiation, 2001-08, Vol.8 (8), p.841-849

2001

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mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E

Molecular and Cellular Biology, 2004-01, Vol.24 (1), p.200-216

2004

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Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway

Molecular cell, 2002-07, Vol.10 (1), p.151-162

2002

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Inactivation of the Tuberous Sclerosis Complex-1 and -2 Gene Products Occurs by Phosphoinositide 3-Kinase/Akt-dependent and -independent Phosphorylation of Tuberin

The Journal of biological chemistry, 2003-09, Vol.278 (39), p.37288-37296

2003

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Tuberous Sclerosis Complex-1 and -2 Gene Products Function Together to Inhibit Mammalian Target of Rapamycin (mTOR)-Mediated Downstream Signaling

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (21), p.13571-13576

2002

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Caspase Cleavage of Initiation Factor 4E-Binding Protein 1 Yields a Dominant Inhibitor of Cap-Dependent Translation and Reveals a Novel Regulatory Motif

Molecular and Cellular Biology, 2002-03, Vol.22 (6), p.1674-1683

2002

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Metastatic castration-resistant prostate cancer hungers for leucine

JNCI : Journal of the National Cancer Institute, 2013-10, Vol.105 (19), p.1427-1428

Tee, Andrew R

2013

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Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis

The Journal of biological chemistry, 2023-01, Vol.299 (1), p.102788-102788, Article 102788

2023

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mTORC1 drives HIF-1[alpha] and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3

Oncogene, 2015-04, Vol.34 (17), p.2239

2015

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Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb

Current biology, 2003-08, Vol.13 (15), p.1259-1268

2003

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The zinc finger/RING domain protein Unkempt regulates cognitive flexibility

Scientific reports, 2021-08, Vol.11 (1), p.16299-16299, Article 16299

2021

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Control of HIF-1α and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock

American journal of physiology. Lung cellular and molecular physiology, 2010-10, Vol.299 (4), p.L455-L471

2010

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The Tuberous Sclerosis Protein TSC2 Is Not Required for the Regulation of the Mammalian Target of Rapamycin by Amino Acids and Certain Cellular Stresses

The Journal of biological chemistry, 2005-05, Vol.280 (19), p.18717-18727

2005

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Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

The Journal of cell biology, 2006-04, Vol.173 (2), p.279-289

2006

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Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability

Biochemical journal, 2003-08, Vol.373 (3), p.999-999

2003

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Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability

Biochemical journal, 2003-06, Vol.372 (Pt 2), p.555-566

2003

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Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1

FEBS letters, 2005-08, Vol.579 (21), p.4763-4768

2005

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mTOR and autophagy: A dynamic relationship governed by nutrients and energy

Possible Targets for Nonimmunosuppressive Therapy of Graves' Orbitopathy

Reversal of Pathological Features of Graves' Orbitopathy by Activation of Forkhead Transcription Factors, FOXOs

Absence of the Birt-Hogg-Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3

Mammalian target of rapamycin complex 1: Signalling inputs, substrates and feedback mechanisms

mTOR, translational control and human disease

DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling

Staurosporine inhibits phosphorylation of translational regulators linked to mTOR

mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E

Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway

Inactivation of the Tuberous Sclerosis Complex-1 and -2 Gene Products Occurs by Phosphoinositide 3-Kinase/Akt-dependent and -independent Phosphorylation of Tuberin

Tuberous Sclerosis Complex-1 and -2 Gene Products Function Together to Inhibit Mammalian Target of Rapamycin (mTOR)-Mediated Downstream Signaling

Caspase Cleavage of Initiation Factor 4E-Binding Protein 1 Yields a Dominant Inhibitor of Cap-Dependent Translation and Reveals a Novel Regulatory Motif

Metastatic castration-resistant prostate cancer hungers for leucine

Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis

mTORC1 drives HIF-1[alpha] and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3

Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb

The zinc finger/RING domain protein Unkempt regulates cognitive flexibility

Control of HIF-1α and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock

The Tuberous Sclerosis Protein TSC2 Is Not Required for the Regulation of the Mammalian Target of Rapamycin by Amino Acids and Certain Cellular Stresses

Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability

Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability

Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1

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