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Dietary intervention as a therapeutic for cancer

Cancer science, 2021-02, Vol.112 (2), p.498-504

2021

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Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

Nature communications, 2017-10, Vol.8 (1), p.1177-15, Article 1177

2017

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Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial–mesenchymal transition

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (43), p.15526-15531

2014

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Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer‐specific metabolism

Cancer science, 2017-05, Vol.108 (5), p.931-940

2017

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Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma

Nature communications, 2023-12, Vol.14 (1), p.8095-8095, Article 8095

2023

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Ppp6c haploinsufficiency accelerates UV‐induced BRAF(V600E)‐initiated melanomagenesis

Cancer science, 2021-06, Vol.112 (6), p.2233-2244

2021

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Structural Basis of Beneficial Design for Effective Nicotinamide Phosphoribosyltransferase Inhibitors

Molecules (Basel, Switzerland), 2020-08, Vol.25 (16), p.3633

2020

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Robustness of a Cancer Profiling Test Using Formalin-fixed Paraffin Embedded Tumor Specimens

Anticancer research, 2021-03, Vol.41 (3), p.1341-1348

2021

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Divergent metabolic responses dictate vulnerability to NAMPT inhibition in ovarian cancer

FEBS letters, 2020-05, Vol.594 (9), p.1379-1388

2020

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Comparison of the ischemic and non-ischemic lung cancer metabolome reveals hyper activity of the TCA cycle and autophagy

Biochemical and biophysical research communications, 2020-09, Vol.530 (1), p.285-291

2020

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Oncogenic K‐RasG12V cannot overcome proliferation failure caused by loss of Ppp6c in mouse embryonic fibroblasts

FEBS open bio, 2024-04, Vol.14 (4), p.545-554

2024

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PP6 deficiency in mice with KRAS mutation and Trp53 loss promotes early death by PDAC with cachexia‐like features

Cancer science, 2022-05, Vol.113 (5), p.1613-1624

2022

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Novel activating KRAS mutation candidates in lung adenocarcinoma

Biochemical and biophysical research communications, 2020-02, Vol.522 (3), p.690-696

2020

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Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species

International journal of oncology, 2018-03, Vol.52 (3), p.881-891

2018

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Loss of protein phosphatase 6 in mouse keratinocytes enhances K‐rasG12D‐driven tumor promotion

Cancer science, 2018-07, Vol.109 (7), p.2178-2187

2018

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Revisiting glucose metabolism in cancer: lessons from a PKM knock-in model

Molecular & cellular oncology, 2018-07, Vol.5 (4), p.e1472054-e1472054

2018

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Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming

PloS one, 2015-07, Vol.10 (7), p.e0132789-e0132789

2015

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Loss of protein phosphatase 6 in mouse keratinocytes increases susceptibility to ultraviolet-B-induced carcinogenesis

Cancer letters, 2015-09, Vol.365 (2), p.223-228

2015

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Mice doubly-deficient in the Arf GAPs SMAP1 and SMAP2 exhibit embryonic lethality

FEBS letters, 2015-09, Vol.589 (19), p.2754-2762

2015

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Ppp6c deficiency accelerates K‐rasG12D‐induced tongue carcinogenesis

Cancer medicine (Malden, MA), 2021-07, Vol.10 (13), p.4451-4464

2021

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Nuclear Inhibitor of Protein Phosphatase-1 (NIPP1) Directs Protein Phosphatase-1 (PP1) to Dephosphorylate the U2 Small Nuclear Ribonucleoprotein Particle (snRNP) Component, Spliceosome-associated Protein 155 (Sap155)

The Journal of biological chemistry, 2008-12, Vol.283 (51), p.35805-35814

2008

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Usage of Tautomycetin, a Novel Inhibitor of Protein Phosphatase 1 (PP1), Reveals That PP1 Is a Positive Regulator of Raf-1 in Vivo

The Journal of biological chemistry, 2003-01, Vol.278 (1), p.82-88

2003

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DUSP13B/TMDP inhibits stress-activated MAPKs and suppresses AP-1-dependent gene expression

Molecular and cellular biochemistry, 2011-06, Vol.352 (1-2), p.155-162

2011

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A metabolic vulnerability of small-cell lung cancer

Oncotarget, 2018-08, Vol.9 (64), p.32278-32279

2018

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Dietary intervention as a therapeutic for cancer

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial–mesenchymal transition

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth

Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer‐specific metabolism

Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma

Ppp6c haploinsufficiency accelerates UV‐induced BRAF(V600E)‐initiated melanomagenesis

Structural Basis of Beneficial Design for Effective Nicotinamide Phosphoribosyltransferase Inhibitors

Robustness of a Cancer Profiling Test Using Formalin-fixed Paraffin Embedded Tumor Specimens

Divergent metabolic responses dictate vulnerability to NAMPT inhibition in ovarian cancer

Comparison of the ischemic and non-ischemic lung cancer metabolome reveals hyper activity of the TCA cycle and autophagy

Oncogenic K‐RasG12V cannot overcome proliferation failure caused by loss of Ppp6c in mouse embryonic fibroblasts

PP6 deficiency in mice with KRAS mutation and Trp53 loss promotes early death by PDAC with cachexia‐like features

Novel activating KRAS mutation candidates in lung adenocarcinoma

Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species

Loss of protein phosphatase 6 in mouse keratinocytes enhances K‐rasG12D‐driven tumor promotion

Revisiting glucose metabolism in cancer: lessons from a PKM knock-in model

Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming

Loss of protein phosphatase 6 in mouse keratinocytes increases susceptibility to ultraviolet-B-induced carcinogenesis

Mice doubly-deficient in the Arf GAPs SMAP1 and SMAP2 exhibit embryonic lethality

Ppp6c deficiency accelerates K‐rasG12D‐induced tongue carcinogenesis

Nuclear Inhibitor of Protein Phosphatase-1 (NIPP1) Directs Protein Phosphatase-1 (PP1) to Dephosphorylate the U2 Small Nuclear Ribonucleoprotein Particle (snRNP) Component, Spliceosome-associated Protein 155 (Sap155)

Usage of Tautomycetin, a Novel Inhibitor of Protein Phosphatase 1 (PP1), Reveals That PP1 Is a Positive Regulator of Raf-1 in Vivo

DUSP13B/TMDP inhibits stress-activated MAPKs and suppresses AP-1-dependent gene expression

A metabolic vulnerability of small-cell lung cancer

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