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FGF19 and FGF21: In NASH we trust

Molecular metabolism (Germany), 2021-04, Vol.46, p.101152-101152, Article 101152

2021

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Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases

Trends in pharmacological sciences (Regular ed.), 2011-09, Vol.32 (9), p.543-550

2011

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Vitreous metabolomics profiling of proliferative diabetic retinopathy

Diabetologia, 2021-01, Vol.64 (1), p.70-82

2021

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Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

Nature medicine, 2012-09, Vol.18 (9), p.1407-1412

2012

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GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

Cell, 2010-09, Vol.142 (5), p.687-698

2010

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LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes

Nature medicine, 2015-03, Vol.21 (3), p.239-247

2015

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A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

Cell metabolism, 2016-03, Vol.23 (3), p.427-440

2016

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Topological Phase Transition in MoTe2: A Review

Physica status solidi. PSS-RRL. Rapid research letters, 2023-06, Vol.17 (6), p.n/a

2023

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Inhibition of Grb14, a negative modulator of insulin signaling, improves glucose homeostasis without causing cardiac dysfunction

Scientific reports, 2020-02, Vol.10 (1), p.3417, Article 3417

2020

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Free fatty acid receptor 4 activation protects against choroidal neovascularization in mice

Angiogenesis (London), 2020-08, Vol.23 (3), p.385-394

2020

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Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3

Cell metabolism, 2012-09, Vol.16 (3), p.311-321

2012

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Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice

Diabetes (New York, N.Y.), 2018-05, Vol.67 (5), p.974-985

2018

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NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids

Cell, 2013-09, Vol.155 (1), p.200-214

2013

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Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa

Experimental and Molecular Medicine, 2021, 53(0), , pp.1-11

2021

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Pharmacokinetics (PK), pharmacodynamics (PD) and integrated PK/PD modeling of a novel long acting FGF21 clinical candidate PF-05231023 in diet-induced obese and leptin-deficient obese mice

PloS one, 2015-03, Vol.10 (3), p.e0119104-e0119104

2015

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Omega-3/Omega-6 Long-Chain Fatty Acid Imbalance in Phase I Retinopathy of Prematurity

Nutrients, 2022-03, Vol.14 (7), p.1333

2022

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Long-Acting FGF21 Inhibits Retinal Vascular Leakage in In Vivo and In Vitro Models

International journal of molecular sciences, 2020-02, Vol.21 (4), p.1188

2020

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The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317

Journal of lipid research, 2006-11, Vol.47 (11), p.2451-2461

2006

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Photoreceptor glucose metabolism determines normal retinal vascular growth

EMBO molecular medicine, 2018-01, Vol.10 (1), p.76-90

2018

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Discovery of a new class of integrin antibodies for fibrosis

Scientific reports, 2021-01, Vol.11 (1), p.2118-15, Article 2118

2021

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FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice

Cell reports (Cambridge), 2017-02, Vol.18 (7), p.1606-1613

2017

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Fibroblast growth factor 21 improves insulin sensitivity and synergizes with insulin in human adipose stem cell-derived (hASC) adipocytes

PloS one, 2014-11, Vol.9 (11), p.e111767

2014

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Knock-down of IL-1Ra in obese mice decreases liver inflammation and improves insulin sensitivity

PloS one, 2014-09, Vol.9 (9), p.e107487-e107487

2014

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Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice

PloS one, 2010-11, Vol.5 (11), p.e13959

2010

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FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis

Molecular metabolism (Germany), 2017-06, Vol.6 (6), p.471-481

2017

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FGF19 and FGF21: In NASH we trust

Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases

Vitreous metabolomics profiling of proliferative diabetic retinopathy

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes

A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

Topological Phase Transition in MoTe2: A Review

Inhibition of Grb14, a negative modulator of insulin signaling, improves glucose homeostasis without causing cardiac dysfunction

Free fatty acid receptor 4 activation protects against choroidal neovascularization in mice

Maintenance of Metabolic Homeostasis by Sestrin2 and Sestrin3

Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice

NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids

Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa

Pharmacokinetics (PK), pharmacodynamics (PD) and integrated PK/PD modeling of a novel long acting FGF21 clinical candidate PF-05231023 in diet-induced obese and leptin-deficient obese mice

Omega-3/Omega-6 Long-Chain Fatty Acid Imbalance in Phase I Retinopathy of Prematurity

Long-Acting FGF21 Inhibits Retinal Vascular Leakage in In Vivo and In Vitro Models

The mechanism mediating the activation of acetyl-coenzyme A carboxylase-α gene transcription by the liver X receptor agonist T0-901317

Photoreceptor glucose metabolism determines normal retinal vascular growth

Discovery of a new class of integrin antibodies for fibrosis

FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice

Fibroblast growth factor 21 improves insulin sensitivity and synergizes with insulin in human adipose stem cell-derived (hASC) adipocytes

Knock-down of IL-1Ra in obese mice decreases liver inflammation and improves insulin sensitivity

Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice

FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis

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