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An orally active motilin receptor antagonist, MA-2029, inhibits motilin-induced gastrointestinal motility, increase in fundic tone, and diarrhea in conscious dogs without affecting gastric emptying

European journal of pharmacology, 2009-08, Vol.615 (1), p.185-192

2009

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Oral administration of MA-2029, a novel selective and competitive motilin receptor antagonist, inhibits motilin-induced intestinal contractions and visceral pain in rabbits

European journal of pharmacology, 2008-03, Vol.581 (3), p.296-305

2008

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Effects of Oral Mitemcinal (GM-611), Erythromycin, EM-574 and Cisapride on Gastric Emptying in Conscious Rhesus Monkeys

Digestive diseases and sciences, 2008-04, Vol.53 (4), p.912-918

2008

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MITEMCINAL (GM-611), AN ORALLY ACTIVE MOTILIN RECEPTOR AGONIST, IMPROVES DELAYED GASTRIC EMPTYING IN A CANINE MODEL OF DIABETIC GASTROPARESIS

Clinical and experimental pharmacology & physiology, 2008-07, Vol.35 (7), p.788-796

2008

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Assessment of the carcinogenic potential of mitemcinal (GM-611): Increased incidence of malignant lymphoma in a rat carcinogenicity study

Toxicology and applied pharmacology, 2008-04, Vol.228 (1), p.1-7

2008

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In vitro Pharmacological Characterization of Mitemcinal (GM-611), the First Acid-Resistant Non-Peptide Motilin Receptor Agonist, in Smooth Muscle of Rabbit Small Intestine

Pharmacology, 2007-01, Vol.79 (3), p.137-148

2007

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Characterization of Multinuclear Hepatocytes Induced in Rats by Mitemcinal (GM-611), an Erythromycin Derivative

Toxicologic pathology, 2008-10, Vol.36 (6), p.858-865

2008

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Effects of Mitemcinal (GM-611), an Acid-Resistant Nonpeptide Motilin Receptor Agonist, on the Gastrointestinal Contractile Activity in Conscious Dogs

Pharmacology, 2007-01, Vol.79 (4), p.223-235

2007

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HEMODYNAMIC AND ELECTROPHYSIOLOGICAL EFFECTS OF MITEMCINAL (GM-611), A NOVEL PROKINETIC AGENT DERIVED FROM ERYTHROMYCIN IN A HALOTHANE-ANESTHETIZED CANINE MODEL

The Journal of Toxicological Sciences, 2007, Vol.32(3), pp.231-239

2007

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PRECLINICAL ELECTROPHYSIOLOGY ASSAYS OF MITEMCINAL (GM-611), A NOVEL PROKINETIC AGENT DERIVED FROM ERYTHROMYCIN

The Journal of Toxicological Sciences, 2007, Vol.32(3), pp.217-230

2007

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Motilides: A long and winding road. Lessons from mitemcinal (GM-611) on diabetic gastroparesis

Regulatory peptides, 2009-06, Vol.155 (1-3), p.18-23

2009

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Motilides: A long and winding road

Regulatory peptides, 2009-06, Vol.155 (1), p.18-23

2009

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Design and Synthesis of N-terminal Cyclic Motilin Partial Peptides: A Novel Pure Motilin Antagonist

Chemical and Pharmaceutical Bulletin, 2001, Vol.49(1), pp.40-43

2001

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Potent, acid-stable and orally active macrolide-type motilin receptor agonists, GM-611 and the derivatives

Bioorganic & medicinal chemistry letters, 1994-06, Vol.4 (11), p.1347-1352

1994

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Structure-Activity Study of Intact Porcine Motilin

Chemical and Pharmaceutical Bulletin, 1999/11/15, Vol.47(11), pp.1555-1559

1999

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ORAL MITEMCINAL (GM-611), AN ERYTHROMYCIN-DERIVED PROKINETIC, ACCELERATES NORMAL AND EXPERIMENTALLY DELAYED GASTRIC EMPTYING IN CONSCIOUS DOGS

Clinical and experimental pharmacology & physiology, 2008-01, Vol.35 (1), p.35-42

2008

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Effects of motilin and mitemcinal (GM-611) on gastrointestinal contractile activity in rhesus monkeys in vivo and in vitro

Digestive diseases and sciences, 2007-11, Vol.52 (11), p.3112-3122

2007

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Effects of mitemcinal (GM-611), an orally active erythromycin-derived prokinetic agent, on delayed gastric emptying and postprandial glucose in a new minipig model of diabetes

Journal of diabetes and its complications, 2008-09, Vol.22 (5), p.339-347

2008

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P-30 Assessment of The Carcinogenic Potential of Mitemcinal (GM-611): Increased Incidence of Malignant Lymphoma in a Rat Carcinogenicity Study

Journal of Toxicologic Pathology, 2008, Vol.21 (2), p.152-152

2008

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Design and Synthesis of Motilin Antagonists Derived from the [1−4] Fragment of Porcine Motilin

Journal of medicinal chemistry, 2002-01, Vol.45 (3), p.670-675

2002

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Design and Synthesis of Novel Tetra-Peptide Motilin Agonists

Bioorganic & medicinal chemistry, 2002-06, Vol.10 (6), p.1805-1811

2002

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Design and Synthesis of N-terminal Cyclic Motilin Partial Peptides

Chemical & pharmaceutical bulletin, 2001-01, Vol.49 (1), p.40

2001

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Effect of dual inhibition of 5-alpha-reductase and aromatase on spontaneously developed canine prostatic hypertrophy

The Prostate, 1998-10, Vol.37 (2), p.70-76

1998

Volltextzugriff (PDF)

Differential effects of buspirone on gastric motility and emptying in rats

Japanese Journal of Pharmacology, 1996, Vol.71 (suppl.1), p.111-111

1996

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Vasodilative mechanism of [Leu13]-motilin in canine isolated mesenteric artery

Japanese Journal of Pharmacology, 1998, Vol.76 (suppl.1), p.145-145

1998

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An orally active motilin receptor antagonist, MA-2029, inhibits motilin-induced gastrointestinal motility, increase in fundic tone, and diarrhea in conscious dogs without affecting gastric emptying

Oral administration of MA-2029, a novel selective and competitive motilin receptor antagonist, inhibits motilin-induced intestinal contractions and visceral pain in rabbits

Effects of Oral Mitemcinal (GM-611), Erythromycin, EM-574 and Cisapride on Gastric Emptying in Conscious Rhesus Monkeys

MITEMCINAL (GM-611), AN ORALLY ACTIVE MOTILIN RECEPTOR AGONIST, IMPROVES DELAYED GASTRIC EMPTYING IN A CANINE MODEL OF DIABETIC GASTROPARESIS

Assessment of the carcinogenic potential of mitemcinal (GM-611): Increased incidence of malignant lymphoma in a rat carcinogenicity study

In vitro Pharmacological Characterization of Mitemcinal (GM-611), the First Acid-Resistant Non-Peptide Motilin Receptor Agonist, in Smooth Muscle of Rabbit Small Intestine

Characterization of Multinuclear Hepatocytes Induced in Rats by Mitemcinal (GM-611), an Erythromycin Derivative

Effects of Mitemcinal (GM-611), an Acid-Resistant Nonpeptide Motilin Receptor Agonist, on the Gastrointestinal Contractile Activity in Conscious Dogs

HEMODYNAMIC AND ELECTROPHYSIOLOGICAL EFFECTS OF MITEMCINAL (GM-611), A NOVEL PROKINETIC AGENT DERIVED FROM ERYTHROMYCIN IN A HALOTHANE-ANESTHETIZED CANINE MODEL

PRECLINICAL ELECTROPHYSIOLOGY ASSAYS OF MITEMCINAL (GM-611), A NOVEL PROKINETIC AGENT DERIVED FROM ERYTHROMYCIN

Motilides: A long and winding road. Lessons from mitemcinal (GM-611) on diabetic gastroparesis

Motilides: A long and winding road

Design and Synthesis of N-terminal Cyclic Motilin Partial Peptides: A Novel Pure Motilin Antagonist

Potent, acid-stable and orally active macrolide-type motilin receptor agonists, GM-611 and the derivatives

Structure-Activity Study of Intact Porcine Motilin

ORAL MITEMCINAL (GM-611), AN ERYTHROMYCIN-DERIVED PROKINETIC, ACCELERATES NORMAL AND EXPERIMENTALLY DELAYED GASTRIC EMPTYING IN CONSCIOUS DOGS

Effects of motilin and mitemcinal (GM-611) on gastrointestinal contractile activity in rhesus monkeys in vivo and in vitro

Effects of mitemcinal (GM-611), an orally active erythromycin-derived prokinetic agent, on delayed gastric emptying and postprandial glucose in a new minipig model of diabetes

P-30 Assessment of The Carcinogenic Potential of Mitemcinal (GM-611): Increased Incidence of Malignant Lymphoma in a Rat Carcinogenicity Study

Design and Synthesis of Motilin Antagonists Derived from the [1−4] Fragment of Porcine Motilin

Design and Synthesis of Novel Tetra-Peptide Motilin Agonists

Design and Synthesis of N-terminal Cyclic Motilin Partial Peptides

Effect of dual inhibition of 5-alpha-reductase and aromatase on spontaneously developed canine prostatic hypertrophy

Differential effects of buspirone on gastric motility and emptying in rats

Vasodilative mechanism of [Leu13]-motilin in canine isolated mesenteric artery

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