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Possibility of Exosome-Based Therapeutics and Challenges in Production of Exosomes Eligible for Therapeutic Application

Biological and Pharmaceutical Bulletin, 2018/06/01, Vol.41(6), pp.835-842

2018

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Pharmacokinetics of Exosomes—An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2265-2269

2017

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Therapeutic Application of Small Extracellular Vesicles (sEVs): Pharmaceutical and Pharmacokinetic Challenges

Biological and Pharmaceutical Bulletin, 2020/04/01, Vol.43(4), pp.576-583

2020

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Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection

Journal of biotechnology, 2013-05, Vol.165 (2), p.77-84

2013

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Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics

European journal of pharmaceutical sciences, 2017-01, Vol.96, p.316-322

2017

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Antitumor immunity by small extracellular vesicles collected from activated dendritic cells through effective induction of cellular and humoral immune responses

Biomaterials, 2020-09, Vol.252, p.120112-120112, Article 120112

2020

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Development of allergic rhinitis immunotherapy using antigen-loaded small extracellular vesicles

Journal of controlled release, 2022-05, Vol.345, p.433-442

2022

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Effect of exosome isolation methods on physicochemical properties of exosomes and clearance of exosomes from the blood circulation

European journal of pharmaceutics and biopharmaceutics, 2016-01, Vol.98, p.1-8

2016

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Determining The Role of Surface Glycans in The Pharmacokinetics of Small Extracellular Vesicles

Journal of pharmaceutical sciences, 2021-09, Vol.110 (9), p.3261-3267

2021

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Calcium Peroxide-Containing Polydimethylsiloxane-Based Microwells for Inhibiting Cell Death in Spheroids through Improved Oxygen Supply

Biological and Pharmaceutical Bulletin, 2021/10/01, Vol.44(10), pp.1458-1464

2021

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DNA nanotechnology-based composite-type gold nanoparticle-immunostimulatory DNA hydrogel for tumor photothermal immunotherapy

Biomaterials, 2017-11, Vol.146, p.136-145

2017

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Development of DNA-anchored assembly of small extracellular vesicle for efficient antigen delivery to antigen presenting cells

Biomaterials, 2019-12, Vol.225, p.119518-119518, Article 119518

2019

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Enhanced Class I Tumor Antigen Presentation via Cytosolic Delivery of Exosomal Cargos by Tumor-Cell-Derived Exosomes Displaying a pH-Sensitive Fusogenic Peptide

Molecular pharmaceutics, 2017-11, Vol.14 (11), p.4079-4086

2017

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Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice

Journal of pharmaceutical sciences, 2015-02, Vol.104 (2), p.705-713

2015

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Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice

Molecular therapy, 2020-10, Vol.28 (10), p.2203-2219

2020

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Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells

Cancer science, 2017-09, Vol.108 (9), p.1803-1810

2017

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The Expert of the Medicine Explains “Understanding of the Novel Coronavirus Vaccine”

YAKUGAKU ZASSHI, 2022/06/01, Vol.142(6), pp.597-599

2022

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Optimization of Albumin Secretion and Metabolic Activity of Cytochrome P450 1A1 of Human Hepatoblastoma HepG2 Cells in Multicellular Spheroids by Controlling Spheroid Size

Biological and Pharmaceutical Bulletin, 2017/03/01, Vol.40(3), pp.334-338

2017

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Development of RNA/DNA Hydrogel Targeting Toll-Like Receptor 7/8 for Sustained RNA Release and Potent Immune Activation

Molecules (Basel, Switzerland), 2020-02, Vol.25 (3), p.728

2020

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Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice

Journal of extracellular vesicles, 2015-01, Vol.4 (1), p.26238-n/a

2015

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Effects of Localization of Antigen Proteins in Antigen-Loaded Exosomes on Efficiency of Antigen Presentation

Molecular pharmaceutics, 2019-06, Vol.16 (6), p.2309-2314

2019

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In Vivo Tracking of Extracellular Vesicles in Mice Using Fusion Protein Comprising Lactadherin and Gaussia Luciferase

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1660, p.245

2017

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New modality medicines: Expectations for DDS Research

Drug delivery system, 2023, Vol.38 (1)

2023

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Development of CD40L-modified tumor small extracellular vesicles for effective induction of antitumor immune response

Nanomedicine (London, England), 2020-07, Vol.15 (17), p.1641-1652

2020

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Nonviral vector-mediated RNA interference: Its gene silencing characteristics and important factors to achieve RNAi-based gene therapy

Advanced drug delivery reviews, 2009-07, Vol.61 (9), p.760-766

2009

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Possibility of Exosome-Based Therapeutics and Challenges in Production of Exosomes Eligible for Therapeutic Application

Pharmacokinetics of Exosomes—An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics

Therapeutic Application of Small Extracellular Vesicles (sEVs): Pharmaceutical and Pharmacokinetic Challenges

Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection

Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics

Antitumor immunity by small extracellular vesicles collected from activated dendritic cells through effective induction of cellular and humoral immune responses

Development of allergic rhinitis immunotherapy using antigen-loaded small extracellular vesicles

Effect of exosome isolation methods on physicochemical properties of exosomes and clearance of exosomes from the blood circulation

Determining The Role of Surface Glycans in The Pharmacokinetics of Small Extracellular Vesicles

Calcium Peroxide-Containing Polydimethylsiloxane-Based Microwells for Inhibiting Cell Death in Spheroids through Improved Oxygen Supply

DNA nanotechnology-based composite-type gold nanoparticle-immunostimulatory DNA hydrogel for tumor photothermal immunotherapy

Development of DNA-anchored assembly of small extracellular vesicle for efficient antigen delivery to antigen presenting cells

Enhanced Class I Tumor Antigen Presentation via Cytosolic Delivery of Exosomal Cargos by Tumor-Cell-Derived Exosomes Displaying a pH-Sensitive Fusogenic Peptide

Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice

Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice

Accelerated growth of B16BL6 tumor in mice through efficient uptake of their own exosomes by B16BL6 cells

The Expert of the Medicine Explains “Understanding of the Novel Coronavirus Vaccine”

Optimization of Albumin Secretion and Metabolic Activity of Cytochrome P450 1A1 of Human Hepatoblastoma HepG2 Cells in Multicellular Spheroids by Controlling Spheroid Size

Development of RNA/DNA Hydrogel Targeting Toll-Like Receptor 7/8 for Sustained RNA Release and Potent Immune Activation

Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice

Effects of Localization of Antigen Proteins in Antigen-Loaded Exosomes on Efficiency of Antigen Presentation

In Vivo Tracking of Extracellular Vesicles in Mice Using Fusion Protein Comprising Lactadherin and Gaussia Luciferase

New modality medicines: Expectations for DDS Research

Development of CD40L-modified tumor small extracellular vesicles for effective induction of antitumor immune response

Nonviral vector-mediated RNA interference: Its gene silencing characteristics and important factors to achieve RNAi-based gene therapy

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