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A conformational restriction approach to the development of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease

Bioorganic & medicinal chemistry, 2003-10, Vol.11 (20), p.4389-4415

2003

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Pharmacological Characterization of RS-1259, an Orally Active Dual Inhibitor of Acetylcholinesterase and Serotonin Transporter, in Rodents: Possible Treatment of Alzheimer’s Disease

Journal of Pharmacological Sciences, 2003, Vol.93(1), pp.95-105

2003

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Stereospecific Construction of Contiguous Quaternary and Tertiary Stereocenters by Rearrangement from Indoline-2-methanol to 2,2,3-Trisubstituted Tetrahydroquinoline: Application to an Efficient Total Synthesis of Natural Virantmycin

Angewandte Chemie International Edition, 2003-06, Vol.42 (22), p.2540-2543

2003

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Design and Synthesis of Dual Inhibitors of Acetylcholinesterase and Serotonin Transporter Targeting Potential Agents for Alzheimer's Disease

Organic letters, 2002-10, Vol.4 (20), p.3359-3362

2002

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Discovery of novel pyrrole derivatives as potent agonists for the niacin receptor GPR109A

Bioorganic & medicinal chemistry letters, 2020-05, Vol.30 (10), p.127105, Article 127105

2020

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Total Synthesis of (+)-Benzastatin E via Diastereoselective Grignard Addition to 2-Acylindoline

Organic letters, 2003-02, Vol.5 (3), p.269-271

2003

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Design, synthesis and structure–Activity relationships of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease

Bioorganic & medicinal chemistry, 2003-05, Vol.11 (9), p.1935-1955

2003

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Alutacenoic Acids A and B, Rare Naturally Occurring Cyclopropenone Derivatives Isolated from Fungi: Potent Non-Peptide Factor XIIIa Inhibitors

Journal of the American Chemical Society, 2000-03, Vol.122 (8), p.1842-1843

2000

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A highly stereoselective synthesis of plaunotol and its thiourea derivatives as potent antibacterial agents against Helicobacter pylori

Bioorganic & medicinal chemistry letters, 1999-05, Vol.9 (10), p.1347-1350

1999

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Stereospecific synthesis of 2,2,3-trisubstituted tetrahydroquinolines: application to the total syntheses of benzastatin E and natural virantmycin

Tetrahedron, 2005-02, Vol.61 (8), p.2075-2104

2005

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Practical and Effective Total Synthesis of Plaunotol via Novel and Stereoselective Method for Construction of Tri-substituted Olefins

Journal of Synthetic Organic Chemistry, Japan, 2001, Vol.59(10), pp.971-984

2001

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A Highly Stereoselective Synthesis of ( E)-α-Bromoacrylates

Tetrahedron, 2000-11, Vol.56 (45), p.8825-8831

2000

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Pharmacological Characterization of RS-1259, an Orally Active Dual Inhibitor of Acetylcholinesterase and Serotonin Transporter, in Rodents: Possible Treatment of Alzheimer’s Disease

Journal of pharmacological sciences, 2003, Vol.93 (4), p.95-105

2003

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Corrigendum to “A highly stereoselective synthesis of (E)-α-bromoacrylates”: [Tetrahedron 56 (2000) 8825]

Tetrahedron, 2001-09, Vol.57 (39), p.8405-8405

2001

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Schizostatin, a potent squalene synthase inhibitor from Schizophyllum commune: Isolation, structure elucidation, and total synthesis

Tetrahedron letters, 1995-08, Vol.36 (35), p.6301-6304

1995

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Schizostatin, a Novel Squalene Synthase Inhibitor Produced by the Mushroom, Schizophyllum commune: I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities

The Journal of Antibiotics, 1996/07/25, Vol.49(7), pp.617-623

1996

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Schizostatin, a Novel Squalene Synthase Inhibitor Produced by the Mushroom, Schizophyllum commune: II. Structure Elucidation and Total Synthesis

The Journal of Antibiotics, 1996/07/25, Vol.49(7), pp.624-630

1996

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Schizostatin, a Novel Squalene Synthase Inhibitor Produced by the Mushroom, Schizophylllum commune. II. Structure Elucidation and Total Synthesis

Journal of antibiotics, 1996, Vol.49 (7), p.624-630

1996

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Bis(2,2,2-trifluoroethyl)bromophosphonoacetate, a Novel HWE Reagent for the Preparation of (E)-α-Bromoacrylates: A General and Stereoselective Method for the Synthesis of Trisubstituted Alkenes

Organic letters, 2000-06, Vol.2 (13), p.1975-1978

2000

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Synthesis of Plaunotol Derivatives and their Antibacterial Activities against Helicobacter pylori

Bioorganic & medicinal chemistry, 2001-07, Vol.9 (7), p.1781-1791

2001

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Conformational analysis and docking study of potent factor XIIIa inhibitors having a cyclopropenone ring

Journal of molecular graphics & modelling, 2000-12, Vol.18 (6), p.591-599

2000

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A practical total synthesis of plaunotol via highly Z-selective Wittig olefination of α-acetal ketones

Perkin 1 : an international journal of organic and bio-organic chemistry, 2000 (13), p.2073-2078

2000

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Stereospecific Construction of Contiguous Quaternary and Tertiary Stereocenters by Rearrangement from Indoline-2-methanol to 2,2,3-Trisubstituted Tetrahydroquinoline: Application to an Efficient Total Synthesis of Natural Virantmycin

Angewandte Chemie, 2003-06, Vol.115 (22), p.2644-2647

2003

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Versatile Synthon for Chirally [beta]-Deuterated L-Amino Acids and Synthesis of (3R)- and (3S)-[3-2H1]-L-Serine

Bioscience, biotechnology, and biochemistry, 1996-08, Vol.60 (8), p.1248

1996

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Conformational Analysis and Docking Study of Potent Acetylcholinesterase Inhibitors Having a Benzylamine Moiety

Chem-Bio Informatics Journal, 2003, Vol.3(2), pp.46-57

2003

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A conformational restriction approach to the development of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease

Pharmacological Characterization of RS-1259, an Orally Active Dual Inhibitor of Acetylcholinesterase and Serotonin Transporter, in Rodents: Possible Treatment of Alzheimer’s Disease

Stereospecific Construction of Contiguous Quaternary and Tertiary Stereocenters by Rearrangement from Indoline-2-methanol to 2,2,3-Trisubstituted Tetrahydroquinoline: Application to an Efficient Total Synthesis of Natural Virantmycin

Design and Synthesis of Dual Inhibitors of Acetylcholinesterase and Serotonin Transporter Targeting Potential Agents for Alzheimer's Disease

Discovery of novel pyrrole derivatives as potent agonists for the niacin receptor GPR109A

Total Synthesis of (+)-Benzastatin E via Diastereoselective Grignard Addition to 2-Acylindoline

Design, synthesis and structure–Activity relationships of dual inhibitors of acetylcholinesterase and serotonin transporter as potential agents for Alzheimer's disease

Alutacenoic Acids A and B, Rare Naturally Occurring Cyclopropenone Derivatives Isolated from Fungi: Potent Non-Peptide Factor XIIIa Inhibitors

A highly stereoselective synthesis of plaunotol and its thiourea derivatives as potent antibacterial agents against Helicobacter pylori

Stereospecific synthesis of 2,2,3-trisubstituted tetrahydroquinolines: application to the total syntheses of benzastatin E and natural virantmycin

Practical and Effective Total Synthesis of Plaunotol via Novel and Stereoselective Method for Construction of Tri-substituted Olefins

A Highly Stereoselective Synthesis of ( E)-α-Bromoacrylates

Pharmacological Characterization of RS-1259, an Orally Active Dual Inhibitor of Acetylcholinesterase and Serotonin Transporter, in Rodents: Possible Treatment of Alzheimer’s Disease

Corrigendum to “A highly stereoselective synthesis of (E)-α-bromoacrylates”: [Tetrahedron 56 (2000) 8825]

Schizostatin, a potent squalene synthase inhibitor from Schizophyllum commune: Isolation, structure elucidation, and total synthesis

Schizostatin, a Novel Squalene Synthase Inhibitor Produced by the Mushroom, Schizophyllum commune: I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities

Schizostatin, a Novel Squalene Synthase Inhibitor Produced by the Mushroom, Schizophyllum commune: II. Structure Elucidation and Total Synthesis

Schizostatin, a Novel Squalene Synthase Inhibitor Produced by the Mushroom, Schizophylllum commune. II. Structure Elucidation and Total Synthesis

Bis(2,2,2-trifluoroethyl)bromophosphonoacetate, a Novel HWE Reagent for the Preparation of (E)-α-Bromoacrylates: A General and Stereoselective Method for the Synthesis of Trisubstituted Alkenes

Synthesis of Plaunotol Derivatives and their Antibacterial Activities against Helicobacter pylori

Conformational analysis and docking study of potent factor XIIIa inhibitors having a cyclopropenone ring

A practical total synthesis of plaunotol via highly Z-selective Wittig olefination of α-acetal ketones

Stereospecific Construction of Contiguous Quaternary and Tertiary Stereocenters by Rearrangement from Indoline-2-methanol to 2,2,3-Trisubstituted Tetrahydroquinoline: Application to an Efficient Total Synthesis of Natural Virantmycin

Versatile Synthon for Chirally [beta]-Deuterated L-Amino Acids and Synthesis of (3R)- and (3S)-[3-2H1]-L-Serine

Conformational Analysis and Docking Study of Potent Acetylcholinesterase Inhibitors Having a Benzylamine Moiety

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