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Mitochondria are physiologically maintained at close to 50 °C

PLoS biology, 2018-01, Vol.16 (1), p.e2003992-e2003992

2018

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Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Cell, 2016-10, Vol.167 (2), p.457-470.e13

2016

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A Mitochondrial Ribosomal and RNA Decay Pathway Blocks Cell Proliferation

Current biology, 2013-03, Vol.23 (6), p.535-541

2013

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Mitochondrial DNA replication proceeds via a 'bootlace' mechanism involving the incorporation of processed transcripts

Nucleic acids research, 2013-06, Vol.41 (11), p.5837

2013

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Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter

Nature structural & molecular biology, 2011-11, Vol.18 (11), p.1281

2011

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Unique features of DNA replication in mitochondria: A functional and evolutionary perspective

BioEssays, 2014-11, Vol.36 (11), p.1024-1031

2014

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A rolling circle replication mechanism produces multimeric lariats of mitochondrial DNA in Caenorhabditis elegans

PLoS genetics, 2015-02, Vol.11 (2), p.e1004985-e1004985

2015

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Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (30), p.9334-9339

2015

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Alternative oxidase expression in the mouse enables bypassing cytochrome c oxidase blockade and limits mitochondrial ROS overproduction

PLoS genetics, 2013-01, Vol.9 (1), p.e1003182

2013

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Mitochondrial temperature homeostasis resists external metabolic stresses

eLife, 2023-12, Vol.12

2023

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Analysis of replication intermediates indicates that Drosophila melanogaster mitochondrial DNA replicates by a strand-coupled theta mechanism

PloS one, 2013-01, Vol.8 (1), p.e53249-e53249

2013

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Somatic mtDNA Mutations Cause Aging Phenotypes without Affecting Reactive Oxygen Species Production

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (50), p.17993-17998

2005

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Alternative oxidase‐mediated respiration prevents lethal mitochondrial cardiomyopathy

EMBO molecular medicine, 2019-01, Vol.11 (1), p.n/a

2019

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Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth

PloS one, 2016-01, Vol.11 (1), p.e0145836

2016

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Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms

PLoS genetics, 2019-10, Vol.15 (10), p.e1008410

2019

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Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand

The EMBO journal, 2006-11, Vol.25 (22), p.5358-5371

2006

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Expression of the Ciona intestinalis Alternative Oxidase (AOX) in Drosophila Complements Defects in Mitochondrial Oxidative Phosphorylation

Cell metabolism, 2009-05, Vol.9 (5), p.449-460

2009

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Mitochondrial medicine: A metabolic perspective on the pathology of oxidative phosphorylation disorders

Cell metabolism, 2006-01, Vol.3 (1), p.9-13

2006

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Minimal effects of spargel (PGC-1) overexpression in a Drosophila mitochondrial disease model

Biology open, 2019, Vol.8 (7)

2019

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Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase

Scientific reports, 2018-07, Vol.8 (1), p.10882-10, Article 10882

2018

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Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (20), p.9105-9110

2010

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Mitochondrial transcription terminator family members mTTF and mTerf5 have opposing roles in coordination of mtDNA synthesis

PLoS genetics, 2013-09, Vol.9 (9), p.e1003800-e1003800

2013

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Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology

Disease models & mechanisms, 2017-02, Vol.10 (2), p.163-171

2017

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Human Heart Mitochondrial DNA Is Organized in Complex Catenated Networks Containing Abundant Four-way Junctions and Replication Forks

The Journal of biological chemistry, 2009-08, Vol.284 (32), p.21446-21457

2009

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Mammalian Mitochondrial DNA Replication Intermediates Are Essentially Duplex but Contain Extensive Tracts of RNA/DNA Hybrid

Journal of molecular biology, 2010-04, Vol.397 (5), p.1144-1155

2010

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Mitochondria are physiologically maintained at close to 50 °C

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

A Mitochondrial Ribosomal and RNA Decay Pathway Blocks Cell Proliferation

Mitochondrial DNA replication proceeds via a 'bootlace' mechanism involving the incorporation of processed transcripts

Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter

Unique features of DNA replication in mitochondria: A functional and evolutionary perspective

A rolling circle replication mechanism produces multimeric lariats of mitochondrial DNA in Caenorhabditis elegans

Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication

Alternative oxidase expression in the mouse enables bypassing cytochrome c oxidase blockade and limits mitochondrial ROS overproduction

Mitochondrial temperature homeostasis resists external metabolic stresses

Analysis of replication intermediates indicates that Drosophila melanogaster mitochondrial DNA replicates by a strand-coupled theta mechanism

Somatic mtDNA Mutations Cause Aging Phenotypes without Affecting Reactive Oxygen Species Production

Alternative oxidase‐mediated respiration prevents lethal mitochondrial cardiomyopathy

Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth

Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms

Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand

Expression of the Ciona intestinalis Alternative Oxidase (AOX) in Drosophila Complements Defects in Mitochondrial Oxidative Phosphorylation

Mitochondrial medicine: A metabolic perspective on the pathology of oxidative phosphorylation disorders

Minimal effects of spargel (PGC-1) overexpression in a Drosophila mitochondrial disease model

Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase

Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction

Mitochondrial transcription terminator family members mTTF and mTerf5 have opposing roles in coordination of mtDNA synthesis

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology

Human Heart Mitochondrial DNA Is Organized in Complex Catenated Networks Containing Abundant Four-way Junctions and Replication Forks

Mammalian Mitochondrial DNA Replication Intermediates Are Essentially Duplex but Contain Extensive Tracts of RNA/DNA Hybrid

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