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1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity

Antimicrobial Agents and Chemotherapy, 1997-05, Vol.41 (5), p.1082-1093

1997

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Retroviral-Mediated Gene Therapy for the Treatment of Hepatocellular carcinoma: An Innovative Approach for Cancer Therapy

Proceedings of the National Academy of Sciences - PNAS, 1991-09, Vol.88 (18), p.8039-8043

1991

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Amino Acid Ester Prodrugs of Acyclovir

Antiviral chemistry & chemotherapy, 1992-06, Vol.3 (3), p.157-164

1992

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2-amino-6-methoxypurine arabinoside: an agent for T-cell malignancies

Cancer research (Chicago, Ill.), 1995-08, Vol.55 (15), p.3352-3356

1995

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Review of research leading to new anti-herpesvirus agents in clinical development: Valaciclovir hydrochloride (256u, the L-valyl ester of acyclovir) and 882c, a specific agent for varicella zoster virus

HERPES: A GLOBAL CHALLENGE, 1993, Vol.41 (S1), p.139-145

1993

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6-Methoxypurine arabinoside as a selective and potent inhibitor of varicella-zoster virus

Antimicrobial Agents and Chemotherapy, 1991-05, Vol.35 (5), p.851-857

1991

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Metabolism and pharmacokinetics of a double prodrug of ganciclovir in the rat and monkey

Drug metabolism and disposition, 1995-11, Vol.23 (11), p.1242

1995

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Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents

Journal of medicinal chemistry, 1993, Vol.36 (1), p.119-125

1993

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The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology

Structure (London), 1997-10, Vol.5 (10), p.1373-1383

1997

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Effects of acyclovir and its metabolites on purine nucleoside phosphorylase

The Journal of biological chemistry, 1984-04, Vol.259 (7), p.4065-4069

1984

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Effects of 3′-azido-3′-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells

Biochemical and biophysical research communications, 1988-07, Vol.154 (1), p.124-129

1988

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6-deoxyacyclovir: A Xanthine Oxidase-Activated Prodrug of Acyclovir

Proceedings of the National Academy of Sciences - PNAS, 1984-05, Vol.81 (10), p.3209-3213

1984

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Xanthine oxidase from human liver: Purification and characterization

Archives of biochemistry and biophysics, 1986-05, Vol.247 (1), p.108-119

1986

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5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile

Antimicrobial Agents and Chemotherapy, 1994-07, Vol.38 (7), p.1590-1603

1994

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Metabolic disposition and pharmacokinetics of the antiviral agent 6-methoxypurine arabinoside in rats and monkeys

Antimicrobial Agents and Chemotherapy, 1991-06, Vol.35 (6), p.1165-1173

1991

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Nucleotide analogue inhibitors of purine nucleoside phosphorylase

The Journal of biological chemistry, 1990-02, Vol.265 (6), p.3066-3069

1990

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Selective anabolism of 6-methoxypurine arabinoside in varicella-zoster virus-infected cells

Antimicrobial Agents and Chemotherapy, 1991-10, Vol.35 (10), p.2116-2120

1991

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Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agents

Journal of medicinal chemistry, 1986-01, Vol.29 (1), p.138-143

1986

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6-N-substituted derivatives of adenine arabinoside as selective inhibitors of varicella-zoster virus

Antimicrobial Agents and Chemotherapy, 1991-07, Vol.35 (7), p.1437-1443

1991

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Nucleoside hydrolases from Trypanosoma cruzi

The Journal of biological chemistry, 1984-04, Vol.259 (8), p.5073-5077

1984

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A novel human phosphotransferase highly specific for adenosine

Archives of biochemistry and biophysics, 1992-07, Vol.296 (1), p.161-169

1992

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Varicella-Zoster virus thymidine kinase: Characterization and substrate specificity

Biochemical pharmacology, 1993-12, Vol.46 (12), p.2209-2218

1993

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Novel 6-alkoxypurine 2',3'-dideoxynucleosides as inhibitors of the cytopathic effect of the human immunodeficiency virus

Journal of medicinal chemistry, 1993-02, Vol.36 (3), p.378-384

1993

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Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution

The Journal of biological chemistry, 1990-08, Vol.265 (23), p.14016-14022

1990

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Purine phosphoribosyltransferases from Leishmania donovani

The Journal of biological chemistry, 1980-02, Vol.255 (3), p.909-916

1980

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1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity

Retroviral-Mediated Gene Therapy for the Treatment of Hepatocellular carcinoma: An Innovative Approach for Cancer Therapy

Amino Acid Ester Prodrugs of Acyclovir

2-amino-6-methoxypurine arabinoside: an agent for T-cell malignancies

Review of research leading to new anti-herpesvirus agents in clinical development: Valaciclovir hydrochloride (256u, the L-valyl ester of acyclovir) and 882c, a specific agent for varicella zoster virus

6-Methoxypurine arabinoside as a selective and potent inhibitor of varicella-zoster virus

Metabolism and pharmacokinetics of a double prodrug of ganciclovir in the rat and monkey

Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents

The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology

Effects of acyclovir and its metabolites on purine nucleoside phosphorylase

Effects of 3′-azido-3′-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells

6-deoxyacyclovir: A Xanthine Oxidase-Activated Prodrug of Acyclovir

Xanthine oxidase from human liver: Purification and characterization

5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile

Metabolic disposition and pharmacokinetics of the antiviral agent 6-methoxypurine arabinoside in rats and monkeys

Nucleotide analogue inhibitors of purine nucleoside phosphorylase

Selective anabolism of 6-methoxypurine arabinoside in varicella-zoster virus-infected cells

Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agents

6-N-substituted derivatives of adenine arabinoside as selective inhibitors of varicella-zoster virus

Nucleoside hydrolases from Trypanosoma cruzi

A novel human phosphotransferase highly specific for adenosine

Varicella-Zoster virus thymidine kinase: Characterization and substrate specificity

Novel 6-alkoxypurine 2',3'-dideoxynucleosides as inhibitors of the cytopathic effect of the human immunodeficiency virus

Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution

Purine phosphoribosyltransferases from Leishmania donovani

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