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Synthesis and Biological Evaluation of Cytotoxic Analogs of Somatostatin Containing Doxorubicin or Its Intensely Potent Derivative, 2-pyrrolinodoxorubicin

Proceedings of the National Academy of Sciences - PNAS, 1998-02, Vol.95 (4), p.1794-1799

1998

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Hypothalamic Hormones and Cancer

Frontiers in neuroendocrinology, 2001-10, Vol.22 (4), p.248-291

2001

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Growth inhibition of experimental pancreatic cancers and sustained reduction in epidermal growth factor receptors during therapy with hormonal peptide analogs

Journal of cancer research and clinical oncology, 1999-08, Vol.125 (8-9), p.444-452

1999

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New approaches to therapy of cancers of the stomach, colon and pancreas based on peptide analogs

Cellular and molecular life sciences : CMLS, 2004-04, Vol.61 (9), p.1042-1068

2004

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Bombesin antagonists inhibit proangiogenic factors in human experimental breast cancers

British journal of cancer, 2004-01, Vol.90 (1), p.245-252

2004

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Cytotoxic Analogs of Luteinizing Hormone-Releasing Hormone Containing Doxorubicin or 2-Pyrrolinodoxorubicin, a Derivative 500-1000 Times More Potent

Proceedings of the National Academy of Sciences - PNAS, 1996-07, Vol.93 (14), p.7269-7273

1996

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Effective Treatment of Metastatic MDA-MB-435 Human Estrogen-independent Breast Carcinomas with a Targeted Cytotoxic Analogue of Luteinizing Hormone-releasing Hormone AN-207

Clinical cancer research, 2000-10, Vol.6 (10), p.4158-4165

2000

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Inhibition of growth of OV-1063 human epithelial ovarian cancers and c-jun and c-fos oncogene expression by bombesin antagonists

British journal of cancer, 2000-10, Vol.83 (7), p.906-913

2000

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Targeting of Cytotoxic Somatostatin Analog AN-238 to Somatostatin Receptor Subtypes 5 and/or 3 in Experimental Pancreatic Cancers

Clinical cancer research, 2001-09, Vol.7 (9), p.2854-2861

2001

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Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers

British journal of cancer, 2000-05, Vol.82 (10), p.1724-1731

2000

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A targeted cytotoxic somatostatin (SST) analogue, AN-238, inhibits the growth of H-69 small-cell lung carcinoma (SCLC) and H-157 non-SCLC in nude mice

European journal of cancer (1990), 2001-03, Vol.37 (5), p.620-628

2001

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Growth inhibition of human ovarian cancers by cytotoxic analogues of luteinizing hormone-releasing hormone

JNCI : Journal of the National Cancer Institute, 1997-12, Vol.89 (23), p.1803-1809

1997

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Antagonists of growth hormone-releasing hormone (GH-RH) inhibit in vivo proliferation of experimental pancreatic cancers and decrease IGF-II levels in tumours

European journal of cancer (1990), 2000, Vol.36 (1), p.128-136

2000

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Targeted cytotoxic analogue of bombesin/ gastrin-releasing peptide inhibits the growth of H-69 human small-cell lung carcinoma in nude mice

British Journal of Cancer, 1999-11, Vol.81 (6), p.966-971

1999

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Inhibition of growth of androgen-independent DU-145 prostate cancer in vivo by luteinising hormone-releasing hormone antagonist cetrorelix and bombesin antagonists RC-3940-II and RC-3950-II

European journal of cancer (1990), 1997-06, Vol.33 (7), p.1141-1148

1997

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Inhibition of Growth of Human Osteosarcomas by Antagonists of Growth Hormone-Releasing Hormone

JNCI : Journal of the National Cancer Institute, 1995-12, Vol.87 (23), p.1787-1794

1995

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The Expression of the Pituitary Growth Hormone-Releasing Hormone Receptor and Its Splice Variants in Normal and Neoplastic Human Tissues

Proceedings of the National Academy of Sciences - PNAS, 2005-11, Vol.102 (48), p.17424-17429

2005

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Effective treatment of experimental U-87MG human glioblastoma in nude mice with a targeted cytotoxic bombesin analogue, AN-215

British journal of cancer, 2002-04, Vol.86 (8), p.1322-1327

2002

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Calcitonin-secreting ovarian strumal carcinoid

European journal of gynaecological oncology, 1994, Vol.15 (3), p.211

1994

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Targeting of doxorubicin to ES-2 human ovarian cancers in nude mice by linking to an analog of luteinizing hormone-releasing hormone improves its effectiveness

International journal of oncology, 2001-09, Vol.19 (3), p.571

2001

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Inhibition of growth of MDA-MB-231 human breast cancer xenografts in nude mice by bombesin/gastrin-releasing peptide (GRP) antagonists RC-3940-II and RC-3095

European journal of cancer (1990), 1998-04, Vol.34 (5), p.710-717

1998

Volltextzugriff (PDF)

Inhibition of Growth of OV-1063 Human Epithelial Ovarian Cancer Xenografts in Nude Mice by Treatment with Luteinizing Hormone-Releasing Hormone Antagonist SB-75

Proceedings of the National Academy of Sciences - PNAS, 1994-07, Vol.91 (15), p.7090-7094

1994

Volltextzugriff (PDF)

The Expression of Growth Hormone-Releasing Hormone (GHRH) and Splice Variants of Its Receptor in Human Gastroenteropancreatic Carcinomas

Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (18), p.11866-11871

2002

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Inhibitory Effect of Antagonists of Bombesin and Growth Hormone-Releasing Hormone on Orthotopic and Intraosseous Growth and Invasiveness of PC-3 Human Prostate Cancer in Nude Mice

Clinical cancer research, 2005-01, Vol.11 (1), p.49-57

2005

Volltextzugriff (PDF)

Preclinical Evaluation of Targeted Cytotoxic Luteinizing Hormone-Releasing Hormone Analogue AN-152 in Androgen-Sensitive and Insensitive Prostate Cancers

Clinical cancer research, 2003-10, Vol.9 (12), p.4505-4513

2003

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Synthesis and Biological Evaluation of Cytotoxic Analogs of Somatostatin Containing Doxorubicin or Its Intensely Potent Derivative, 2-pyrrolinodoxorubicin

Hypothalamic Hormones and Cancer

Growth inhibition of experimental pancreatic cancers and sustained reduction in epidermal growth factor receptors during therapy with hormonal peptide analogs

New approaches to therapy of cancers of the stomach, colon and pancreas based on peptide analogs

Bombesin antagonists inhibit proangiogenic factors in human experimental breast cancers

Cytotoxic Analogs of Luteinizing Hormone-Releasing Hormone Containing Doxorubicin or 2-Pyrrolinodoxorubicin, a Derivative 500-1000 Times More Potent

Effective Treatment of Metastatic MDA-MB-435 Human Estrogen-independent Breast Carcinomas with a Targeted Cytotoxic Analogue of Luteinizing Hormone-releasing Hormone AN-207

Inhibition of growth of OV-1063 human epithelial ovarian cancers and c-jun and c-fos oncogene expression by bombesin antagonists

Targeting of Cytotoxic Somatostatin Analog AN-238 to Somatostatin Receptor Subtypes 5 and/or 3 in Experimental Pancreatic Cancers

Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers

A targeted cytotoxic somatostatin (SST) analogue, AN-238, inhibits the growth of H-69 small-cell lung carcinoma (SCLC) and H-157 non-SCLC in nude mice

Growth inhibition of human ovarian cancers by cytotoxic analogues of luteinizing hormone-releasing hormone

Antagonists of growth hormone-releasing hormone (GH-RH) inhibit in vivo proliferation of experimental pancreatic cancers and decrease IGF-II levels in tumours

Targeted cytotoxic analogue of bombesin/ gastrin-releasing peptide inhibits the growth of H-69 human small-cell lung carcinoma in nude mice

Inhibition of growth of androgen-independent DU-145 prostate cancer in vivo by luteinising hormone-releasing hormone antagonist cetrorelix and bombesin antagonists RC-3940-II and RC-3950-II

Inhibition of Growth of Human Osteosarcomas by Antagonists of Growth Hormone-Releasing Hormone

The Expression of the Pituitary Growth Hormone-Releasing Hormone Receptor and Its Splice Variants in Normal and Neoplastic Human Tissues

Effective treatment of experimental U-87MG human glioblastoma in nude mice with a targeted cytotoxic bombesin analogue, AN-215

Calcitonin-secreting ovarian strumal carcinoid

Targeting of doxorubicin to ES-2 human ovarian cancers in nude mice by linking to an analog of luteinizing hormone-releasing hormone improves its effectiveness

Inhibition of growth of MDA-MB-231 human breast cancer xenografts in nude mice by bombesin/gastrin-releasing peptide (GRP) antagonists RC-3940-II and RC-3095

Inhibition of Growth of OV-1063 Human Epithelial Ovarian Cancer Xenografts in Nude Mice by Treatment with Luteinizing Hormone-Releasing Hormone Antagonist SB-75

The Expression of Growth Hormone-Releasing Hormone (GHRH) and Splice Variants of Its Receptor in Human Gastroenteropancreatic Carcinomas

Inhibitory Effect of Antagonists of Bombesin and Growth Hormone-Releasing Hormone on Orthotopic and Intraosseous Growth and Invasiveness of PC-3 Human Prostate Cancer in Nude Mice

Preclinical Evaluation of Targeted Cytotoxic Luteinizing Hormone-Releasing Hormone Analogue AN-152 in Androgen-Sensitive and Insensitive Prostate Cancers

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