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Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

Cell, 1987-10, Vol.51 (2), p.199-209

1987

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Ustekinumab in adolescent patients age 12 to 17 years with moderate-to-severe plaque psoriasis: Results of the randomized phase 3 CADMUS study

Journal of the American Academy of Dermatology, 2015-10, Vol.73 (4), p.594-603

2015

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Guselkumab (an IL-23–specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis

Journal of allergy and clinical immunology, 2014-04, Vol.133 (4), p.1032-1040

2014

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A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis

Molecular and Cellular Biology, 1987-12, Vol.7 (12), p.4568-4571

1987

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Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

The Lancet (British edition), 2008-05, Vol.371 (9625), p.1675-1684

2008

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Ligand-Induced Stimulation of Epidermal Growth Factor Receptor Mutants with Altered Transmembrane Regions

Proceedings of the National Academy of Sciences - PNAS, 1988-12, Vol.85 (24), p.9567-9571

1988

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Glucocorticoid Receptor Ligand Binding Domain Is Sufficient for the Modulation of Glucocorticoid Induction Properties by Homologous Receptors, Coactivator Transcription Intermediary Factor 2, and Ubc9

Molecular endocrinology (Baltimore, Md.), 2005-02, Vol.19 (2), p.290-311

2005

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Kinetic parameters of the protein tyrosine kinase activity of EGF‐receptor mutants with individually altered autophosphorylation sites

The EMBO journal, 1988-10, Vol.7 (10), p.3053-3060

1988

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Modulation of Induction Properties of Glucocorticoid Receptor-Agonist and -Antagonist Complexes by Coactivators Involves Binding to Receptors but Is Independent of Ability of Coactivators to Augment Transactivation

The Journal of biological chemistry, 2002-12, Vol.277 (51), p.49256-49266

2002

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Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor-regulated gene expression

Molecular endocrinology (Baltimore, Md.), 1999-12, Vol.13 (12), p.2108-2121

1999

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A new Cis-acting element involved in tissue-selective glucocorticoid inducibility of tyrosine aminotransferase gene expression

Molecular endocrinology (Baltimore, Md.), 1993-08, Vol.7 (8), p.941-952

1993

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Ustekinumab significantly improves symptoms of anxiety, depression, and skin-related quality of life in patients with moderate-to-severe psoriasis: Results from a randomized, double-blind, placebo-controlled phase III trial

Journal of the American Academy of Dermatology, 2010-09, Vol.63 (3), p.457-465

2010

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Long-term safety experience of ustekinumab in patients with moderate to severe psoriasis (Part II of II): Results from analyses of infections and malignancy from pooled phase II and III clinical trials

Journal of the American Academy of Dermatology, 2012-05, Vol.66 (5), p.742-751

2012

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Underdiagnosis and undertreatment of cardiovascular risk factors in patients with moderate to severe psoriasis

Journal of the American Academy of Dermatology, 2012-07, Vol.67 (1), p.76-85

2012

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CXCL16 Is a Marker of Inflammation, Atherosclerosis, and Acute Coronary Syndromes in Humans

Journal of the American College of Cardiology, 2007-01, Vol.49 (4), p.442-449

2007

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Impact of weight on the efficacy and safety of ustekinumab in patients with moderate to severe psoriasis: Rationale for dosing recommendations

Journal of the American Academy of Dermatology, 2010-10, Vol.63 (4), p.571-579

2010

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Long-term safety experience of ustekinumab in patients with moderate-to-severe psoriasis (Part I of II): Results from analyses of general safety parameters from pooled Phase 2 and 3 clinical trials

Journal of the American Academy of Dermatology, 2012-05, Vol.66 (5), p.731-741

2012

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The Influence of Pravastatin and Atorvastatin on Markers of Oxidative Stress in Hypercholesterolemic Humans

Journal of the American College of Cardiology, 2008-04, Vol.51 (17), p.1653-1662

2008

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Induction Properties of a Transiently Transfected Glucocorticoid-responsive Gene Vary with Glucocorticoid Receptor Concentration

The Journal of biological chemistry, 1996-11, Vol.271 (48), p.30576-30582

1996

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New antiprogestins with partial agonist activity: potential selective progesterone receptor modulators (SPRMs) and probes for receptor- and coregulator-induced changes in progesterone receptor induction properties

Molecular endocrinology (Baltimore, Md.), 2001-02, Vol.15 (2), p.255-270

2001

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Early Dynamics of P-selectin and Interleukin 6 Predicts Outcomes in Ischemic Stroke

Journal of stroke and cerebrovascular diseases, 2015-08, Vol.24 (8), p.1938-1947

2015

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The Factor Binding to the Glucocorticoid Modulatory Element of the Tyrosine Aminotransferase Gene Is a Novel and Ubiquitous Heteromeric Complex (∗)

The Journal of biological chemistry, 1995-09, Vol.270 (37), p.21893-21901

1995

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Restriction enzyme digestions identify discrete domains in the chromatin around the promoter of the mouse alpha 2(I) collagen gene

The Journal of biological chemistry, 1986-08, Vol.261 (24), p.11362-11368

1986

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The L-arginine Pathway in Acute Ischemic Stroke and Severe Carotid Stenosis: Temporal Profiles and Association with Biomarkers and Outcome

Journal of stroke and cerebrovascular diseases, 2014-09, Vol.23 (8), p.2206-2214

2014

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Restriction enzyme digestions identify discrete domains in the chromatin around the promoter of the mouse α2(I) collagen gene

The Journal of biological chemistry, 1986, Vol.261 (24), p.11362-11368

1986

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Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

Ustekinumab in adolescent patients age 12 to 17 years with moderate-to-severe plaque psoriasis: Results of the randomized phase 3 CADMUS study

Guselkumab (an IL-23–specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis

A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

Ligand-Induced Stimulation of Epidermal Growth Factor Receptor Mutants with Altered Transmembrane Regions

Glucocorticoid Receptor Ligand Binding Domain Is Sufficient for the Modulation of Glucocorticoid Induction Properties by Homologous Receptors, Coactivator Transcription Intermediary Factor 2, and Ubc9

Kinetic parameters of the protein tyrosine kinase activity of EGF‐receptor mutants with individually altered autophosphorylation sites

Modulation of Induction Properties of Glucocorticoid Receptor-Agonist and -Antagonist Complexes by Coactivators Involves Binding to Receptors but Is Independent of Ability of Coactivators to Augment Transactivation

Opposing effects of corepressor and coactivators in determining the dose-response curve of agonists, and residual agonist activity of antagonists, for glucocorticoid receptor-regulated gene expression

A new Cis-acting element involved in tissue-selective glucocorticoid inducibility of tyrosine aminotransferase gene expression

Ustekinumab significantly improves symptoms of anxiety, depression, and skin-related quality of life in patients with moderate-to-severe psoriasis: Results from a randomized, double-blind, placebo-controlled phase III trial

Long-term safety experience of ustekinumab in patients with moderate to severe psoriasis (Part II of II): Results from analyses of infections and malignancy from pooled phase II and III clinical trials

Underdiagnosis and undertreatment of cardiovascular risk factors in patients with moderate to severe psoriasis

CXCL16 Is a Marker of Inflammation, Atherosclerosis, and Acute Coronary Syndromes in Humans

Impact of weight on the efficacy and safety of ustekinumab in patients with moderate to severe psoriasis: Rationale for dosing recommendations

Long-term safety experience of ustekinumab in patients with moderate-to-severe psoriasis (Part I of II): Results from analyses of general safety parameters from pooled Phase 2 and 3 clinical trials

The Influence of Pravastatin and Atorvastatin on Markers of Oxidative Stress in Hypercholesterolemic Humans

Induction Properties of a Transiently Transfected Glucocorticoid-responsive Gene Vary with Glucocorticoid Receptor Concentration

New antiprogestins with partial agonist activity: potential selective progesterone receptor modulators (SPRMs) and probes for receptor- and coregulator-induced changes in progesterone receptor induction properties

Early Dynamics of P-selectin and Interleukin 6 Predicts Outcomes in Ischemic Stroke

The Factor Binding to the Glucocorticoid Modulatory Element of the Tyrosine Aminotransferase Gene Is a Novel and Ubiquitous Heteromeric Complex (∗)

Restriction enzyme digestions identify discrete domains in the chromatin around the promoter of the mouse alpha 2(I) collagen gene

The L-arginine Pathway in Acute Ischemic Stroke and Severe Carotid Stenosis: Temporal Profiles and Association with Biomarkers and Outcome

Restriction enzyme digestions identify discrete domains in the chromatin around the promoter of the mouse α2(I) collagen gene

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