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Allyl isothiocyanate, an activator of TRPA1, increases gastric mucosal blood flow through calcitonin gene-related peptide and adrenomedullin in anesthetized rats

Journal of pharmacological sciences, 2023-04, Vol.151 (4), p.187-194

2023

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Juvenile social defeat stress exposure favors in later onset of irritable bowel syndrome-like symptoms in male mice

Scientific reports, 2021-08, Vol.11 (1), p.16276-16276, Article 16276

2021

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The rodent model of impaired gastric motility induced by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia

Journal of pharmacological sciences, 2021-01, Vol.145 (1), p.122-129

2021

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Su1316 – Daikenchuto, a Traditional Japanese (KAMPO) Medicine, Facilitates Gastrointestinal Motility in Isolated Mouse Distal Colons: Role of Trpa1 Channel and Calcitonin Generelated Peptide

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.S-539-S-539

2019

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Su1319 – Kampo Formula Daikenchuto Facilitates Mucosal Hyperemic Responses Through Activation of Trpa1 Channel-Expressing Neurons in Rats

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.S-540-S-540

2019

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EP24 EFFECT OF APREPITANT ON ALLYL ISHOTHIOCYANATE-INDUCED MUCOSAL INFLAMMATION AND GASTRIC MOTILITY IMPAIRMENT IN THE RODENT STOMACH

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.S-1512-S-1512

2024

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Role of transient receptor potential melastatin 2 (TRPM2) channels in visceral nociception and hypersensitivity

Experimental neurology, 2016-11, Vol.285 (Pt A), p.41-50

2016

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5-Fluorouracil induces diarrhea with changes in the expression of inflammatory cytokines and aquaporins in mouse intestines

PloS one, 2013-01, Vol.8 (1), p.e54788

2013

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Role of transient receptor potential melastatin 2 in surgical inflammation and dysmotility in a mouse model of postoperative ileus

American journal of physiology: Gastrointestinal and liver physiology, 2018-07, Vol.315 (1), p.G104-G116

2018

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Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice

Laboratory investigation, 2012-05, Vol.92 (5), p.769-782

2012

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Identification of Indole Alkaloid Structural Units Important for Stimulus-Selective TRPM8 Inhibition: SAR Study of Naturally Occurring Iboga Derivatives

Journal of natural products (Washington, D.C.), 2014-08, Vol.77 (8), p.1831-1838

2014

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Allyl Isothiocyanate, a Pungent Ingredient of Wasabi, Induces Gastric Low-Grade Inflammation in Rats to Lead to the Impaired Gastric Motility; Involvement of Prostaglandin, Capsaicin-Sensitive Sensory Neurons, and Nitric Oxide

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S563-S563

2017

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Neutrophil recruitment is critical for 5-fluorouracil-induced diarrhea and the decrease in aquaporins in the colon

Pharmacological research, 2014-09, Vol.87, p.71-79

2014

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Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine

European journal of pharmacology, 2007-12, Vol.576 (1), p.143-150

2007

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Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon

American journal of physiology: Gastrointestinal and liver physiology, 2009-08, Vol.297 (2), p.G348-G360

2009

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Protective Role of TRPA1 on TRPV1-Expessing Nerve Fibers Against Gastric Mucosal Barrier Break Induced by Allyl-isothiocyanate in Rats

Digestive diseases and sciences, 2022-05, Vol.60 (9), p.2561

2022

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Activation and Inhibition of Thermosensitive TRP Channels by Voacangine, an Alkaloid Present in Voacanga africana, an African Tree

Journal of natural products (Washington, D.C.), 2014-02, Vol.77 (2), p.285-297

2014

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Increased Expression of 5-HT3 and NK1 Receptors in 5-Fluorouracil-Induced Mucositis in Mouse Jejunum

Digestive diseases and sciences, 2013-12, Vol.58 (12), p.3440-3451

2013

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Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: Pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors

Pharmacological research, 2012-09, Vol.66 (3), p.226-234

2012

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Dietary agonists of TRPV1 inhibit gastric acid secretion in mice

Planta medica, 2012-11, Vol.78 (17), p.1801

2012

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Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa

Life sciences (1973), 2004-03, Vol.74 (17), p.2143-2155

2004

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Distribution of transient receptor potential cation channel subfamily V member 1-expressing nerve fibers in mouse esophagus

Histochemistry and cell biology, 2014-12, Vol.142 (6), p.635-644

2014

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1036 Activation of Luminal Chemosensor TRPV1 by Capsaicin Increases Gastric Motility in Conscious Mice Measured by 13C-Acetic Acid Breath Test

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.S-194-S-194

2013

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Studies on the Synthesis and Opioid Agonistic Activities of Mitragynine-Related Indole Alkaloids: Discovery of Opioid Agonists Structurally Different from Other Opioid Ligands

Journal of medicinal chemistry, 2002-04, Vol.45 (9), p.1949-1956

2002

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Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa

Life sciences (1973), 2005-11, Vol.78 (1), p.2-7

2005

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Allyl isothiocyanate, an activator of TRPA1, increases gastric mucosal blood flow through calcitonin gene-related peptide and adrenomedullin in anesthetized rats

Juvenile social defeat stress exposure favors in later onset of irritable bowel syndrome-like symptoms in male mice

The rodent model of impaired gastric motility induced by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia

Su1316 – Daikenchuto, a Traditional Japanese (KAMPO) Medicine, Facilitates Gastrointestinal Motility in Isolated Mouse Distal Colons: Role of Trpa1 Channel and Calcitonin Generelated Peptide

Su1319 – Kampo Formula Daikenchuto Facilitates Mucosal Hyperemic Responses Through Activation of Trpa1 Channel-Expressing Neurons in Rats

EP24 EFFECT OF APREPITANT ON ALLYL ISHOTHIOCYANATE-INDUCED MUCOSAL INFLAMMATION AND GASTRIC MOTILITY IMPAIRMENT IN THE RODENT STOMACH

Role of transient receptor potential melastatin 2 (TRPM2) channels in visceral nociception and hypersensitivity

5-Fluorouracil induces diarrhea with changes in the expression of inflammatory cytokines and aquaporins in mouse intestines

Role of transient receptor potential melastatin 2 in surgical inflammation and dysmotility in a mouse model of postoperative ileus

Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice

Identification of Indole Alkaloid Structural Units Important for Stimulus-Selective TRPM8 Inhibition: SAR Study of Naturally Occurring Iboga Derivatives

Allyl Isothiocyanate, a Pungent Ingredient of Wasabi, Induces Gastric Low-Grade Inflammation in Rats to Lead to the Impaired Gastric Motility; Involvement of Prostaglandin, Capsaicin-Sensitive Sensory Neurons, and Nitric Oxide

Neutrophil recruitment is critical for 5-fluorouracil-induced diarrhea and the decrease in aquaporins in the colon

Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine

Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon

Protective Role of TRPA1 on TRPV1-Expessing Nerve Fibers Against Gastric Mucosal Barrier Break Induced by Allyl-isothiocyanate in Rats

Activation and Inhibition of Thermosensitive TRP Channels by Voacangine, an Alkaloid Present in Voacanga africana, an African Tree

Increased Expression of 5-HT3 and NK1 Receptors in 5-Fluorouracil-Induced Mucositis in Mouse Jejunum

Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: Pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors

Dietary agonists of TRPV1 inhibit gastric acid secretion in mice

Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa

Distribution of transient receptor potential cation channel subfamily V member 1-expressing nerve fibers in mouse esophagus

1036 Activation of Luminal Chemosensor TRPV1 by Capsaicin Increases Gastric Motility in Conscious Mice Measured by 13C-Acetic Acid Breath Test

Studies on the Synthesis and Opioid Agonistic Activities of Mitragynine-Related Indole Alkaloids: Discovery of Opioid Agonists Structurally Different from Other Opioid Ligands

Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa

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