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An overview of CDK3 in cancer: clinical significance and pharmacological implications

Pharmacological research, 2022-06, Vol.180, p.106249-106249, Article 106249

2022

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Discovery of N ,4-Di(1 H -pyrazol-4-yl)pyrimidin-2-amine-Derived CDK2 Inhibitors as Potential Anticancer Agents: Design, Synthesis, and Evaluation

Molecules (Basel, Switzerland), 2023-03, Vol.28 (7), p.2951

2023

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Pharmacologic co-inhibition of Mnks and mTORC1 synergistically suppresses proliferation and perturbs cell cycle progression in blast crisis-chronic myeloid leukemia cells

Cancer letters, 2015-02, Vol.357 (2), p.612-623

2015

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Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division

Frontiers in microbiology, 2022-08, Vol.13, p.967949-967949

2022

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Discovery of 5-(2-(Phenylamino)pyrimidin-4-yl)thiazol-2(3H)-one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation

ChemMedChem, 2014-05, Vol.9 (5), p.962-972

2014

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Prediction of Metabolism by Cytochrome P450 2C9: Alignment and Docking Studies of a Validated Database of Substrates

Journal of medicinal chemistry, 2008-02, Vol.51 (4), p.780-791

2008

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A Systematic Review and Meta-Analysis Considering the Risk for Congenital Heart Defects of Antidepressant Classes and Individual Antidepressants

Drug safety, 2021-03, Vol.44 (3), p.291-312

2021

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Therapeutic Potential of a Novel Vitamin D3 Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding

Biomolecules (Basel, Switzerland), 2022-07, Vol.12 (7), p.960

2022

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Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids

Expert opinion on drug metabolism & toxicology, 2007-04, Vol.3 (2), p.159-168

2007

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Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance

European journal of medicinal chemistry, 2021-03, Vol.213, p.113049, Article 113049

2021

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Application of an Integrative Drug Safety Model for Detection of Adverse Drug Events Associated With Inhibition of Glutathione Peroxidase 1 in Chronic Obstructive Pulmonary Disease

Pharmaceutical research, 2023-06, Vol.40 (6), p.1553-1568

2023

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Chronic Obstructive Pulmonary Disease Adverse Event Signals Associated with Potential Inhibitors of Glutathione Peroxidase 1: A Sequence Symmetry Analysis

Drug safety, 2024, Vol.47 (1), p.59-70

2024

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2-Anilino-4-(1-methyl-1H-pyrazol-4-yl)pyrimidine-derived CDK2 inhibitors as anticancer agents: Design, synthesis & evaluation

Bioorganic & medicinal chemistry, 2023-02, Vol.80, p.117158-117158, Article 117158

2023

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Molecular Modeling Approaches for the Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes

Journal of chemical information and modeling, 2006-11, Vol.46 (6), p.2661-2673

2006

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Proton pump inhibitors may contribute to progression or development of chronic obstructive pulmonary disease—A sequence symmetry analysis approach

Journal of clinical pharmacy and therapeutics, 2021-12, Vol.46 (6), p.1687-1694

2021

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Neuron-specific responses to acetylcholine within the spinal dorsal horn circuits of rodent and primate

Neuropharmacology, 2021-10, Vol.198, p.108755-108755, Article 108755

2021

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Polymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicity

PLoS genetics, 2012-06, Vol.8 (6), p.e1002755

2012

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Combined Structure- and Ligand-Based Approach for the Identification of Inhibitors of AcrAB-TolC in Escherichia coli

ACS infectious diseases, 2023-12, Vol.9 (12), p.2504-2522

2023

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Pharmacologic Inhibition of MNKs in Acute Myeloid Leukemia

Molecular pharmacology, 2015-08, Vol.88 (2), p.380-389

2015

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Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance

Bioorganic chemistry, 2020-12, Vol.105, p.104394-104394, Article 104394

2020

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In Search of Novel CDK8 Inhibitors by Virtual Screening

Journal of chemical information and modeling, 2017-03, Vol.57 (3), p.413-416

2017

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Tripeptide analogues of MG132 as protease inhibitors

Bioorganic & medicinal chemistry, 2019-01, Vol.27 (2), p.436-441

2019

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Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome

Experimental eye research, 2016-05, Vol.146, p.212-223

2016

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An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis

European journal of medicinal chemistry, 2015-10, Vol.103, p.539-550

2015

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Discovery of CDK5 Inhibitors through Structure-Guided Approach

ACS medicinal chemistry letters, 2019-05, Vol.10 (5), p.786-791

2019

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An overview of CDK3 in cancer: clinical significance and pharmacological implications

Discovery of N ,4-Di(1 H -pyrazol-4-yl)pyrimidin-2-amine-Derived CDK2 Inhibitors as Potential Anticancer Agents: Design, Synthesis, and Evaluation

Pharmacologic co-inhibition of Mnks and mTORC1 synergistically suppresses proliferation and perturbs cell cycle progression in blast crisis-chronic myeloid leukemia cells

Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division

Discovery of 5-(2-(Phenylamino)pyrimidin-4-yl)thiazol-2(3H)-one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation

Prediction of Metabolism by Cytochrome P450 2C9: Alignment and Docking Studies of a Validated Database of Substrates

A Systematic Review and Meta-Analysis Considering the Risk for Congenital Heart Defects of Antidepressant Classes and Individual Antidepressants

Therapeutic Potential of a Novel Vitamin D3 Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding

Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids

Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance

Application of an Integrative Drug Safety Model for Detection of Adverse Drug Events Associated With Inhibition of Glutathione Peroxidase 1 in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease Adverse Event Signals Associated with Potential Inhibitors of Glutathione Peroxidase 1: A Sequence Symmetry Analysis

2-Anilino-4-(1-methyl-1H-pyrazol-4-yl)pyrimidine-derived CDK2 inhibitors as anticancer agents: Design, synthesis & evaluation

Molecular Modeling Approaches for the Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes

Proton pump inhibitors may contribute to progression or development of chronic obstructive pulmonary disease—A sequence symmetry analysis approach

Neuron-specific responses to acetylcholine within the spinal dorsal horn circuits of rodent and primate

Polymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicity

Combined Structure- and Ligand-Based Approach for the Identification of Inhibitors of AcrAB-TolC in Escherichia coli

Pharmacologic Inhibition of MNKs in Acute Myeloid Leukemia

Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance

In Search of Novel CDK8 Inhibitors by Virtual Screening

Tripeptide analogues of MG132 as protease inhibitors

Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome

An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis

Discovery of CDK5 Inhibitors through Structure-Guided Approach

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