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Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

British journal of pharmacology, 2000-04, Vol.129 (8), p.1748-1754

2000

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In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461

The Journal of pharmacology and experimental therapeutics, 1997-10, Vol.283 (1), p.157

1997

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Hypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48461

Atherosclerosis, 1995-05, Vol.115 (1), p.45-63

1995

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Antiplatelet and Antiproliferative Effects of SCH 51866, a Novel Type 1 and Type 5 Phosphodiesterase Inhibitor

Journal of cardiovascular pharmacology, 1996-12, Vol.28 (6), p.862-869

1996

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Interaction Between Sympathetic and Renin-angiotensin System

Journal of hypertension, 1984-12, Vol.2 (6), p.581-587

1984

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Modulation of Circulating Endothelin Levels in Hypertension and Endotoxemia in Rats

Journal of cardiovascular pharmacology, 1991-12, Vol.18 (6), p.895-903

1991

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Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats

European journal of pharmacology, 1998-05, Vol.349 (2), p.237-243

1998

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Diet-induced obese mice develop peripheral, but not central, resistance to leptin

The Journal of clinical investigation, 1997-02, Vol.99 (3), p.385-390

1997

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Atrial Natriuretic Factor-Potentiating and Antihypertensive Activity of SCH 34826: An Orally Active Neutral Metalloendopeptidase Inhibitor

Hypertension (Dallas, Tex. 1979), 1990-02, Vol.15 (2), p.152-161

1990

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Neutral metalloendopeptidase inhibitors as ANF potentiators: sites and mechanisms of action

Canadian journal of physiology and pharmacology, 1991-10, Vol.69 (10), p.1628-1635

1991

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Endopeptidase Inhibition in Angiotensin-Induced Hypertension: Effect of SCH 39370 in Sheep

Hypertension (Dallas, Tex. 1979), 1995-07, Vol.26 (1), p.89-94

1995

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Synthesis and pharmacological activity of angiotensin-converting enzyme inhibitors: N-(mercaptoacyl)-4-substituted-(S)-prolines

Journal of medicinal chemistry, 1988-04, Vol.31 (4), p.875-885

1988

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Angiotensin converting enzyme inhibitors: spirapril and related compounds

Journal of medicinal chemistry, 1989-07, Vol.32 (7), p.1600-1606

1989

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Hemodynamic and Hormonal Effects of Neutral Endopeptidase Inhibitor SCH 39370 in Sheep

Hypertension (Dallas, Tex. 1979), 1991-05, Vol.17 (5), p.643-651

1991

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Carboxyalkyl dipeptides with atrial natriuretic factor potentiating and antihypertensive activity

Journal of medicinal chemistry, 1989-04, Vol.32 (4), p.737-739

1989

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Mercaptoacyl aminoacid inhibitors of atriopeptidase. 1. Structure-activity relationship studies of methionine and S-alkylcysteine derivatives

Journal of medicinal chemistry, 1994-07, Vol.37 (15), p.2461-2476

1994

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Synthesis and comparison of some cardiovascular properties of the stereoisomers of labetalol

Journal of medicinal chemistry, 1982-11, Vol.25 (11), p.1363-1370

1982

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Effects of the Antihypertensive Dilevalol on Large Artery Compliance in Anesthetized Dogs

Journal of cardiovascular pharmacology, 1987, Vol.10 Suppl 11, p.S58-S63

1987

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Effects of the Antihypertensive Dilevalol on Aortic Compliance in Anesthetized Dogs

Journal of cardiovascular pharmacology, 1988-07, Vol.12 (1), p.42-50

1988

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Hemodynamic Actions of a Synthetic Atrial Natriuretic Factor

Journal of cardiovascular pharmacology, 1986-09, Vol.8 (5), p.898-905

1986

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Inhibition of endothelial derived relaxing factor (EDRF) aggravates ischemic acute renal failure in anesthetized rats

Naunyn-Schmiedeberg's archives of pharmacology, 1993-09, Vol.348 (3), p.305-310

1993

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Introduction. Emerging concepts underlying drug discovery in congestive heart failure

Drug development research, 1989, Vol.18 (4), p.263-264

1989

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Effects of the Antihypertensive Dilevalol on Large Artery Compliance in Anesthetized Dogs

Journal of cardiovascular pharmacology, 1987, Vol.10 Suppl 11 (Supplement), p.S58-S63

1987

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56 SCH-39370, an inhibitor of neutral metalloendopeptidase potentiates the biological actions and plasma levels of immunoreactive atrial natriuretic factor and lowers blood pressure in the deoxycorticosterone hypertensive rat

Journal of hypertension, 1988-12, Vol.6 (4), p.S715-S715

1988

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Pharmacologic, Metabolic, and Toxicologic Profile of Spirapril (SCH 33844), a New Angiotensin Converting Inhibitor

Journal of cardiovascular pharmacology, 1987, Vol.10 Suppl 7, p.105-108

1987

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Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461

Hypocholesterolemic activity of a novel inhibitor of cholesterol absorption, SCH 48461

Antiplatelet and Antiproliferative Effects of SCH 51866, a Novel Type 1 and Type 5 Phosphodiesterase Inhibitor

Interaction Between Sympathetic and Renin-angiotensin System

Modulation of Circulating Endothelin Levels in Hypertension and Endotoxemia in Rats

Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats

Diet-induced obese mice develop peripheral, but not central, resistance to leptin

Atrial Natriuretic Factor-Potentiating and Antihypertensive Activity of SCH 34826: An Orally Active Neutral Metalloendopeptidase Inhibitor

Neutral metalloendopeptidase inhibitors as ANF potentiators: sites and mechanisms of action

Endopeptidase Inhibition in Angiotensin-Induced Hypertension: Effect of SCH 39370 in Sheep

Synthesis and pharmacological activity of angiotensin-converting enzyme inhibitors: N-(mercaptoacyl)-4-substituted-(S)-prolines

Angiotensin converting enzyme inhibitors: spirapril and related compounds

Hemodynamic and Hormonal Effects of Neutral Endopeptidase Inhibitor SCH 39370 in Sheep

Carboxyalkyl dipeptides with atrial natriuretic factor potentiating and antihypertensive activity

Mercaptoacyl aminoacid inhibitors of atriopeptidase. 1. Structure-activity relationship studies of methionine and S-alkylcysteine derivatives

Synthesis and comparison of some cardiovascular properties of the stereoisomers of labetalol

Effects of the Antihypertensive Dilevalol on Large Artery Compliance in Anesthetized Dogs

Effects of the Antihypertensive Dilevalol on Aortic Compliance in Anesthetized Dogs

Hemodynamic Actions of a Synthetic Atrial Natriuretic Factor

Inhibition of endothelial derived relaxing factor (EDRF) aggravates ischemic acute renal failure in anesthetized rats

Introduction. Emerging concepts underlying drug discovery in congestive heart failure

Effects of the Antihypertensive Dilevalol on Large Artery Compliance in Anesthetized Dogs

56 SCH-39370, an inhibitor of neutral metalloendopeptidase potentiates the biological actions and plasma levels of immunoreactive atrial natriuretic factor and lowers blood pressure in the deoxycorticosterone hypertensive rat

Pharmacologic, Metabolic, and Toxicologic Profile of Spirapril (SCH 33844), a New Angiotensin Converting Inhibitor

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