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Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

British journal of pharmacology, 2000-04, Vol.129 (8), p.1748-1754

2000

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Diet-induced obese mice develop peripheral, but not central, resistance to leptin

The Journal of clinical investigation, 1997-02, Vol.99 (3), p.385-390

1997

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Leptin increases energy expenditure and selectively promotes fat metabolism in ob/ob mice

American journal of physiology. Regulatory, integrative and comparative physiology, 1997-04, Vol.272 (4), p.1204-R1209

1997

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In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461

The Journal of pharmacology and experimental therapeutics, 1997-10, Vol.283 (1), p.157

1997

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Antiplatelet and Antiproliferative Effects of SCH 51866, a Novel Type 1 and Type 5 Phosphodiesterase Inhibitor

Journal of cardiovascular pharmacology, 1996-12, Vol.28 (6), p.862-869

1996

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Inhibition of endothelial derived relaxing factor (EDRF) aggravates ischemic acute renal failure in anesthetized rats

Naunyn-Schmiedeberg's archives of pharmacology, 1993-09, Vol.348 (3), p.305-310

1993

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Atrial Natriuretic Factor-Potentiating and Antihypertensive Activity of SCH 34826: An Orally Active Neutral Metalloendopeptidase Inhibitor

Hypertension (Dallas, Tex. 1979), 1990-02, Vol.15 (2), p.152-161

1990

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SCH 39370, a neutral metalloendopeptidase inhibitor, potentiates biological responses to atrial natriuretic factor and lowers blood pressure in desoxycorticosterone acetate-sodium hypertensive rats

The Journal of pharmacology and experimental therapeutics, 1989-08, Vol.250 (2), p.624

1989

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Modulation of Circulating Endothelin Levels in Hypertension and Endotoxemia in Rats

Journal of cardiovascular pharmacology, 1991-12, Vol.18 (6), p.895-903

1991

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Influence of C-ANF receptor and neutral endopeptidase on pharmacokinetics of ANF in rats

American journal of physiology. Regulatory, integrative and comparative physiology, 1991-01, Vol.260 (1), p.208-R216

1991

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Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats

European journal of pharmacology, 1998-05, Vol.349 (2), p.237-243

1998

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Phosphoramidon does not inhibit endogenous endothelin-1 release stimulated by hemorrhage, cytokines and hypoxia in rats

European journal of pharmacology, 1994-05, Vol.257 (1), p.95-102

1994

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Neutral metalloendopeptidase inhibition : a novel means of circulatory modulation

Journal of hypertension, 1990-12, Vol.8 (7), p.S161-S167

1990

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Phorbol dibutyrate contractions in rabbit aorta: calcium dependence and sensitivity to nitrovasodilators and 8-BR-cyclic GMP

The Journal of pharmacology and experimental therapeutics, 1986-10, Vol.239 (1), p.78

1986

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Inhibitors of PDE1 and PDE5 cGMP phosphodiesterases: patents and therapeutic potential

Expert opinion on therapeutic patents, 1997-06, Vol.7 (6), p.631-639

1997

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Characterization of in vitro and in vivo platelet responses to thrombin and thrombin receptor-activating peptides in guinea pigs

European journal of pharmacology, 1997-02, Vol.321 (1), p.129-135

1997

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Sympathoadrenal stimulation, not endothelin, plays a role in acute pressor response to cyclosporine in anesthetized rats

The Journal of pharmacology and experimental therapeutics, 1992-06, Vol.261 (3), p.994

1992

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Endopeptidase Inhibition in Angiotensin-Induced Hypertension: Effect of SCH 39370 in Sheep

Hypertension (Dallas, Tex. 1979), 1995-07, Vol.26 (1), p.89-94

1995

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SCH 34826: an overview of its profile as a neutral endopeptidase inhibitor and ANF potentiator

Clinical nephrology, 1991-10, Vol.36 (4), p.187

Sybertz, E J

1991

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Phorbol dibutyrate inhibits release and action of endothelium-derived relaxing factor(s) in canine blood vessels

The Journal of pharmacology and experimental therapeutics, 1989-06, Vol.249 (3), p.858

1989

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Elevation of plasma atrial natriuretic peptide in rats with chronic heart failure by SCH 39370, a neutral metalloendopeptidase inhibitor

The Journal of pharmacology and experimental therapeutics, 1990-08, Vol.254 (2), p.641

1990

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Cardiac, coronary and peripheral vascular effects of acetyl glyceryl ether phosphoryl choline in the anesthetized dog

The Journal of pharmacology and experimental therapeutics, 1985-01, Vol.232 (1), p.156

1985

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Synthesis and pharmacological activity of angiotensin-converting enzyme inhibitors: N-(mercaptoacyl)-4-substituted-(S)-prolines

Journal of medicinal chemistry, 1988-04, Vol.31 (4), p.875-885

1988

Volltextzugriff (PDF)

Atrial Natriuretic Factor Potentiating and Hemodynamic Effects of SCH 42495, a New, Neutral Metalloendopeptidase Inhibitor

American journal of hypertension, 1993-05, Vol.6 (5-Pt-1), p.357-368

1993

Volltextzugriff (PDF)

Localization and characterization of neutral metalloendopeptidase (EC 3.4.24.11), the degradative enzyme for atrial natriuretic peptide, in rat kidney using a radioiodinated neutral metalloendopeptidase inhibitor

The Journal of pharmacology and experimental therapeutics, 1992-06, Vol.261 (3), p.1231

1992

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Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

Diet-induced obese mice develop peripheral, but not central, resistance to leptin

Leptin increases energy expenditure and selectively promotes fat metabolism in ob/ob mice

In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461

Antiplatelet and Antiproliferative Effects of SCH 51866, a Novel Type 1 and Type 5 Phosphodiesterase Inhibitor

Inhibition of endothelial derived relaxing factor (EDRF) aggravates ischemic acute renal failure in anesthetized rats

Atrial Natriuretic Factor-Potentiating and Antihypertensive Activity of SCH 34826: An Orally Active Neutral Metalloendopeptidase Inhibitor

SCH 39370, a neutral metalloendopeptidase inhibitor, potentiates biological responses to atrial natriuretic factor and lowers blood pressure in desoxycorticosterone acetate-sodium hypertensive rats

Modulation of Circulating Endothelin Levels in Hypertension and Endotoxemia in Rats

Influence of C-ANF receptor and neutral endopeptidase on pharmacokinetics of ANF in rats

Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats

Phosphoramidon does not inhibit endogenous endothelin-1 release stimulated by hemorrhage, cytokines and hypoxia in rats

Neutral metalloendopeptidase inhibition : a novel means of circulatory modulation

Phorbol dibutyrate contractions in rabbit aorta: calcium dependence and sensitivity to nitrovasodilators and 8-BR-cyclic GMP

Inhibitors of PDE1 and PDE5 cGMP phosphodiesterases: patents and therapeutic potential

Characterization of in vitro and in vivo platelet responses to thrombin and thrombin receptor-activating peptides in guinea pigs

Sympathoadrenal stimulation, not endothelin, plays a role in acute pressor response to cyclosporine in anesthetized rats

Endopeptidase Inhibition in Angiotensin-Induced Hypertension: Effect of SCH 39370 in Sheep

SCH 34826: an overview of its profile as a neutral endopeptidase inhibitor and ANF potentiator

Phorbol dibutyrate inhibits release and action of endothelium-derived relaxing factor(s) in canine blood vessels

Elevation of plasma atrial natriuretic peptide in rats with chronic heart failure by SCH 39370, a neutral metalloendopeptidase inhibitor

Cardiac, coronary and peripheral vascular effects of acetyl glyceryl ether phosphoryl choline in the anesthetized dog

Synthesis and pharmacological activity of angiotensin-converting enzyme inhibitors: N-(mercaptoacyl)-4-substituted-(S)-prolines

Atrial Natriuretic Factor Potentiating and Hemodynamic Effects of SCH 42495, a New, Neutral Metalloendopeptidase Inhibitor

Localization and characterization of neutral metalloendopeptidase (EC 3.4.24.11), the degradative enzyme for atrial natriuretic peptide, in rat kidney using a radioiodinated neutral metalloendopeptidase inhibitor

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