UB Paderborn / Katalog / Suche / in CDI

The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex

Nature chemical biology, 2017-04, Vol.13 (4), p.389

2017

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The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia

PloS one, 2015-07, Vol.10 (7), p.e0131716-e0131716

2015

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Design and Implementation of New, Silicon-Based, Cross-Coupling Reactions: Importance of Silicon−Oxygen Bonds

Accounts of chemical research, 2002-10, Vol.35 (10), p.835-846

2002

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Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a

ACS medicinal chemistry letters, 2014-02, Vol.5 (2), p.205-209

2014

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SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding

Bioorganic & medicinal chemistry letters, 2017-04, Vol.27 (7), p.1576-1583

2017

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Discovery of A‑893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2

ACS medicinal chemistry letters, 2015-06, Vol.6 (6), p.695-700

2015

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Cross-Coupling Reactions of Alkenylsilanolates. Investigation of the Mechanism and Identification of Key Intermediates through Kinetic Analysis

Journal of the American Chemical Society, 2004-04, Vol.126 (15), p.4876-4882

2004

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Fluoride-Free Cross-Coupling of Organosilanols

Journal of the American Chemical Society, 2001-07, Vol.123 (26), p.6439-6440

2001

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Target (In)Validation: A Critical, Sometimes Unheralded, Role of Modern Medicinal Chemistry

ACS medicinal chemistry letters, 2015-06, Vol.6 (6), p.618-621

Sweis, Ramzi F.

2015

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Fluoride-Promoted Cross-Coupling Reactions of Alkenylsilanols. Elucidation of the Mechanism through Spectroscopic and Kinetic Analysis

Journal of the American Chemical Society, 2004-04, Vol.126 (15), p.4865-4875

2004

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Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice

Free radical biology & medicine, 2021-02, Vol.164, p.223-232

2021

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Superoxide produced by mitochondrial site I Q inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice

Free radical biology & medicine, 2021-02, Vol.164, p.223

2021

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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (6), p.1890-1895

2011

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SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT)

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (15), p.3317-3325

2017

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Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5‑Selective Antagonists

ACS medicinal chemistry letters, 2018-11, Vol.9 (11), p.1088-1093

2018

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Cross-Coupling Reactions of Alkenylsilanols with Fluoroalkylsulfonates

Organic letters, 2002-10, Vol.4 (21), p.3771-3774

2002

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Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

ACS medicinal chemistry letters, 2016-12, Vol.7 (12), p.1107-1111

2016

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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Attenuation of hERG binding and improved HDLc-raising efficacy

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2597-2600

2011

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Recent Advances in Small-Molecule Modulation of Epigenetic Targets: Discovery and Development of Histone Methyltransferase and Bromodomain Inhibitors

Annual Reports in Medicinal Chemistry, 2013, Vol.48, p.185-203

2013

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Organosilicon Compounds in Cross‐Coupling Reactions

Metal‐Catalyzed Cross‐Coupling Reactions and More, 2014, p.475-532

2014

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The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia: e0131716

PloS one, 2015-07, Vol.10 (7)

2015

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PREPARATION OF n-BUTYL 4-CHLOROPHENYL SULFIDE

Organic syntheses, 2002, Vol.79, p.43

2002

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Recent Advances in Small-Molecule Modulation of Epigenetic Targets

Annual Reports in Medicinal Chemistry, 2013, Vol.48, p.185-203

2013

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Organosilicon Compounds in Cross-Coupling Reactions

ChemInform, 2005-07, Vol.36 (30), p.no-no

2005

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The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex

The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

Design and Implementation of New, Silicon-Based, Cross-Coupling Reactions: Importance of Silicon−Oxygen Bonds

Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a

SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding

Discovery of A‑893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2

Cross-Coupling Reactions of Alkenylsilanolates. Investigation of the Mechanism and Identification of Key Intermediates through Kinetic Analysis

Fluoride-Free Cross-Coupling of Organosilanols

Target (In)Validation: A Critical, Sometimes Unheralded, Role of Modern Medicinal Chemistry

Fluoride-Promoted Cross-Coupling Reactions of Alkenylsilanols. Elucidation of the Mechanism through Spectroscopic and Kinetic Analysis

Superoxide produced by mitochondrial site IQ inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice

Superoxide produced by mitochondrial site I Q inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice

2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Scaffold design and advancement in HDLc-raising efficacy

SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT)

Optimization of Preclinical Metabolism for Somatostatin Receptor Subtype 5‑Selective Antagonists

Cross-Coupling Reactions of Alkenylsilanols with Fluoroalkylsulfonates

Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes

2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: Attenuation of hERG binding and improved HDLc-raising efficacy

Recent Advances in Small-Molecule Modulation of Epigenetic Targets: Discovery and Development of Histone Methyltransferase and Bromodomain Inhibitors

Organosilicon Compounds in Cross‐Coupling Reactions

The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia: e0131716

PREPARATION OF n-BUTYL 4-CHLOROPHENYL SULFIDE

Recent Advances in Small-Molecule Modulation of Epigenetic Targets

Organosilicon Compounds in Cross-Coupling Reactions

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