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Preclinical pharmacology of AZD2327: a highly selective agonist of the δ-opioid receptor

The Journal of pharmacology and experimental therapeutics, 2011-07, Vol.338 (1), p.195

2011

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Effects of the δ opioid agonist AZD2327 upon operant behaviors and assessment of its potential for abuse

Pharmacology, biochemistry and behavior, 2014-09, Vol.124, p.48-57

2014

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Discriminative stimulus functions of CNS sedative drugs assessed by drug versus drug discrimination procedures in gerbils

Psychopharmacologia, 1998-01, Vol.135 (2), p.201-212

1998

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Reinforcing Effects of Nicotinic Compounds: Intravenous Self-administration in Drug-Naive Mice

Pharmacology, biochemistry and behavior, 1998-06, Vol.60 (2), p.567-573

1998

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Synthesis of Novel GABA Uptake Inhibitors. 3. Diaryloxime and Diarylvinyl Ether Derivatives of Nipecotic Acid and Guvacine as Anticonvulsant Agents

Journal of medicinal chemistry, 1999-09, Vol.42 (18), p.3447-3462

1999

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Synthesis of Novel GABA Uptake Inhibitors. 4. Bioisosteric Transformation and Successive Optimization of Known GABA Uptake Inhibitors Leading to a Series of Potent Anticonvulsant Drug Candidates

Journal of medicinal chemistry, 1999-10, Vol.42 (21), p.4281-4291

1999

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Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice

European journal of pharmacology, 2000-08, Vol.402 (3), p.241-246

2000

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Discriminative stimulus effects of intravenous l-nicotine and nicotine analogs or metabolites in squirrel monkeys

Psychopharmacologia, 1989-01, Vol.99 (2), p.208-212

1989

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Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5 R,6 R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane

European journal of pharmacology, 1998-09, Vol.356 (2), p.109-119

1998

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Muscarinic Agonists with Antipsychotic-like Activity: Structure−Activity Relationships of 1,2,5-Thiadiazole Analogues with Functional Dopamine Antagonist Activity

Journal of medicinal chemistry, 1998-10, Vol.41 (22), p.4378-4384

1998

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The mouse grid-shock analgesia test: pharmacological characterization of latency to vocalization threshold as an index of antinociception

The Journal of pharmacology and experimental therapeutics, 1994-06, Vol.269 (3), p.1021

Swedberg, M D

1994

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Muscarinic Analgesics with Potent and Selective Effects on the Gastrointestinal Tract: Potential Application for the Treatment of Irritable Bowel Syndrome

Journal of medicinal chemistry, 1997-02, Vol.40 (4), p.538-546

1997

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Conformationally Constrained Analogues of the Muscarinic Agonist 3-(4-(Methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine. Synthesis, Receptor Affinity, and Antinociceptive Activity

Journal of medicinal chemistry, 1998-01, Vol.41 (1), p.109-116

1998

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NNC 19-1228 and NNC 22-0031, novel neuroleptics with a mesolimbic-selective behavioral profile

Psychopharmacologia, 1997-01, Vol.129 (2), p.168-178

1997

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Anticonvulsant profile of the imidazoquinazolines NNC 14-0185 and NNC 14-0189 in rats and mice

European journal of pharmacology, 1996-07, Vol.308 (1), p.21-30

1996

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D-16949 (anpirtoline): a novel serotonergic (5-HT1B) psychotherapeutic agent assessed by its discriminative effects in the rat

The Journal of pharmacology and experimental therapeutics, 1992-12, Vol.263 (3), p.1015

1992

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Identification of novel (isoxazole)methylene-1-azabicyclic compounds with high affinity for the central nicotinic cholinergic receptor

Bioorganic & medicinal chemistry letters, 1997-08, Vol.7 (15), p.1963-1968

1997

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3-(3-Alkylthio-1,2,5-thiadiazol-4-yl)-1-azabicycles. Structure—activity relationships for antinociception mediated by central muscarinic receptors

European journal of medicinal chemistry, 1996, Vol.31 (3), p.221-230

1996

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Pharmacological mechanisms of action of flupirtine: a novel, centrally acting, nonopioid analgesic evaluated by its discriminative effects in the rat

The Journal of pharmacology and experimental therapeutics, 1988-09, Vol.246 (3), p.1067

1988

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Drug discrimination procedures: roles of relative stimulus control in two-drug cases

Psychopharmacologia, 1985, Vol.86 (4), p.444-451

1985

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Functionally selective M1 muscarinic agonists. III: Side chains and azacycles contributing to functional muscarinic selectivity among pyrazinylazacycles

Journal of medicinal chemistry, 1995, Vol.38 (18), p.3469-3481

1995

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Drug discrimination procedures: differential characteristics of the drug A vs drug B and the drug A vs drug B vs no drug cases

Psychopharmacologia, 1986-01, Vol.90 (3), p.341-346

1986

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In vivo labeling of the central GABA uptake carrier with 3H-tiagabine

Life sciences (1973), 1992, Vol.51 (24), p.1857-1868

1992

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Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study

The Lancet (British edition), 2010-09, Vol.376 (9744), p.875-885

2010

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Xanomeline : A selective muscarinic agonist for the treatment of Alzheimer's disease: Challenges and opportunities for developing muscarinic receptor subtype-based therapeutic agents

Drug development research, 1997, Vol.40 (2), p.158-170

1997

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Preclinical pharmacology of AZD2327: a highly selective agonist of the δ-opioid receptor

Effects of the δ opioid agonist AZD2327 upon operant behaviors and assessment of its potential for abuse

Discriminative stimulus functions of CNS sedative drugs assessed by drug versus drug discrimination procedures in gerbils

Reinforcing Effects of Nicotinic Compounds: Intravenous Self-administration in Drug-Naive Mice

Synthesis of Novel GABA Uptake Inhibitors. 3. Diaryloxime and Diarylvinyl Ether Derivatives of Nipecotic Acid and Guvacine as Anticonvulsant Agents

Synthesis of Novel GABA Uptake Inhibitors. 4. Bioisosteric Transformation and Successive Optimization of Known GABA Uptake Inhibitors Leading to a Series of Potent Anticonvulsant Drug Candidates

Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice

Discriminative stimulus effects of intravenous l-nicotine and nicotine analogs or metabolites in squirrel monkeys

Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5 R,6 R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane

Muscarinic Agonists with Antipsychotic-like Activity: Structure−Activity Relationships of 1,2,5-Thiadiazole Analogues with Functional Dopamine Antagonist Activity

The mouse grid-shock analgesia test: pharmacological characterization of latency to vocalization threshold as an index of antinociception

Muscarinic Analgesics with Potent and Selective Effects on the Gastrointestinal Tract: Potential Application for the Treatment of Irritable Bowel Syndrome

Conformationally Constrained Analogues of the Muscarinic Agonist 3-(4-(Methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine. Synthesis, Receptor Affinity, and Antinociceptive Activity

NNC 19-1228 and NNC 22-0031, novel neuroleptics with a mesolimbic-selective behavioral profile

Anticonvulsant profile of the imidazoquinazolines NNC 14-0185 and NNC 14-0189 in rats and mice

D-16949 (anpirtoline): a novel serotonergic (5-HT1B) psychotherapeutic agent assessed by its discriminative effects in the rat

Identification of novel (isoxazole)methylene-1-azabicyclic compounds with high affinity for the central nicotinic cholinergic receptor

3-(3-Alkylthio-1,2,5-thiadiazol-4-yl)-1-azabicycles. Structure—activity relationships for antinociception mediated by central muscarinic receptors

Pharmacological mechanisms of action of flupirtine: a novel, centrally acting, nonopioid analgesic evaluated by its discriminative effects in the rat

Drug discrimination procedures: roles of relative stimulus control in two-drug cases

Functionally selective M1 muscarinic agonists. III: Side chains and azacycles contributing to functional muscarinic selectivity among pyrazinylazacycles

Drug discrimination procedures: differential characteristics of the drug A vs drug B and the drug A vs drug B vs no drug cases

In vivo labeling of the central GABA uptake carrier with 3H-tiagabine

Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study

Xanomeline : A selective muscarinic agonist for the treatment of Alzheimer's disease: Challenges and opportunities for developing muscarinic receptor subtype-based therapeutic agents

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