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The Site of Action of Oxazolidinone Antibiotics in Living Bacteria and in Human Mitochondria

Molecular cell, 2007-05, Vol.26 (3), p.393-402

2007

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Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.1034-1040

2000

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Microscale Adaptation of In Vitro Transcription/Translation for High-Throughput Screening of Natural Product Extract Libraries

Chemical biology & drug design, 2015-12, Vol.86 (6), p.1331-1338

2015

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1H Nuclear Magnetic Resonance Study of Oxazolidinone Binding to Bacterial Ribosomes

Antimicrobial Agents and Chemotherapy, 2002-03, Vol.46 (3), p.625-629

2002

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Pyrimidine Thioethers: A Novel Class of HIV-1 Reverse Transcriptase Inhibitors with Activity Against BHAP-Resistant HIV

Journal of medicinal chemistry, 1998-09, Vol.41 (20), p.3793-3803

1998

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H Nuclear Magnetic Resonance Study of Oxazolidinone Binding to Bacterial Ribosomes

Antimicrobial agents and chemotherapy, 2002-03, Vol.46 (3), p.625-629

2002

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A Mutation in Reverse Transcriptase of Bis(heteroaryl)Piperazine-Resistant Human Immunodeficiency Virus Type 1 that Confers Increased Sensitivity to Other Nonnucleoside Inhibitors

Proceedings of the National Academy of Sciences - PNAS, 1993-05, Vol.90 (10), p.4713-4717

1993

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1 H Nuclear Magnetic Resonance Study of Oxazolidinone Binding to Bacterial Ribosomes

Antimicrobial agents and chemotherapy, 2002-03, Vol.46 (3), p.625-629

2002

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An active recombinant p15 RNase H domain is functionally distinct from the RNase H domain associated with human immunodeficiency virus type 1 reverse transcriptase

The Journal of biological chemistry, 1994-08, Vol.269 (34), p.21741-21747

1994

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Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

Nature communications, 2023-09, Vol.14 (1), p.6030-6030, Article 6030

2023

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What is the role of the board‐level technology committee?

The Journal of corporate accounting & finance, 2019-10, Vol.30 (4), p.43-47

2019

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Three year results of Blessed: Expanded access for DeltaRex-G for an intermediate size population with advanced pancreatic cancer and sarcoma (NCT04091295) and individual patient use of DeltaRex-G for solid malignancies (IND# 19130)

Frontiers in Molecular Medicine, 2022-12, Vol.2, p.1092286

2022

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Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action

Journal of bacteriology, 2000-10, Vol.182 (19), p.5325-5331

2000

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The Site of Action of Oxazolidinone Antibiotics in Living Bacteria and in Human Mitochondria

Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives

Microscale Adaptation of In Vitro Transcription/Translation for High-Throughput Screening of Natural Product Extract Libraries

1H Nuclear Magnetic Resonance Study of Oxazolidinone Binding to Bacterial Ribosomes

Pyrimidine Thioethers: A Novel Class of HIV-1 Reverse Transcriptase Inhibitors with Activity Against BHAP-Resistant HIV

H Nuclear Magnetic Resonance Study of Oxazolidinone Binding to Bacterial Ribosomes

(−)-6-Chloro-2-[(1-furo[2,3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a New Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor

A Mutation in Reverse Transcriptase of Bis(heteroaryl)Piperazine-Resistant Human Immunodeficiency Virus Type 1 that Confers Increased Sensitivity to Other Nonnucleoside Inhibitors

1 H Nuclear Magnetic Resonance Study of Oxazolidinone Binding to Bacterial Ribosomes

An active recombinant p15 RNase H domain is functionally distinct from the RNase H domain associated with human immunodeficiency virus type 1 reverse transcriptase

Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells

Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

What is the role of the board‐level technology committee?

Three year results of Blessed: Expanded access for DeltaRex-G for an intermediate size population with advanced pancreatic cancer and sarcoma (NCT04091295) and individual patient use of DeltaRex-G for solid malignancies (IND# 19130)

Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action

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