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A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy

Science advances, 2016-09, Vol.2 (9), p.e1601167-e1601167

2016

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A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication

PLoS pathogens, 2015-03, Vol.11 (3), p.e1004682

2015

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Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (48), p.14834-14839

2015

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Engineering of serine protease for improved thermostability and catalytic activity using rational design

International journal of biological macromolecules, 2019-04, Vol.126, p.229-237

2019

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Investigating the molecular basis of Siah1 and Siah2 E3 ubiquitin ligase substrate specificity

PloS one, 2014-09, Vol.9 (9), p.e106547-e106547

2014

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Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis

Nature (London), 2012-03, Vol.483 (7389), p.355-358

2012

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Crystal Structure of Arabidopsis Cyclophilin38 Reveals a Previously Uncharacterized Immunophilin Fold and a Possible Autoinhibitory Mechanism

The Plant cell, 2012-06, Vol.24 (6), p.2666-2674

2012

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Crystal structure of the PAC1R extracellular domain unifies a consensus fold for hormone recognition by class B G-protein coupled receptors

PloS one, 2011-05, Vol.6 (5), p.e19682-e19682

2011

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Avathrin: a novel thrombin inhibitor derived from a multicopy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum

The FASEB journal, 2017-07, Vol.31 (7), p.2981-2995

2017

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Structure of a diguanylate cyclase from Thermotoga maritima: insights into activation, feedback inhibition and thermostability

PloS one, 2014-10, Vol.9 (10), p.e110912-e110912

2014

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Structural and Functional Studies of trans-Encoded HLA-DQ2.3 (DQA103:01/DQB102:01) Protein Molecule

The Journal of biological chemistry, 2012-04, Vol.287 (17), p.13611-13619

2012

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H2O2 inhibits ABA-signaling protein phosphatase HAB1

PloS one, 2014-12, Vol.9 (12), p.e113643

2014

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α-Glucan pathway as a novel Mtb drug target: structural insights and cues for polypharmcological targeting of GlgB and GlgE

Current medicinal chemistry, 2014-01, Vol.21 (35), p.4074-4084

2014

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Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - experimental validation in human breast and colon cancer

Bioscience, biotechnology, and biochemistry, 2016-11, Vol.80 (11), p.2122-2131

2016

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Crystal structure of thrombin in complex with S-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors

PloS one, 2011-10, Vol.6 (10), p.e26367-e26367

2011

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Validation of drug-like inhibitors against Mycobacterium tuberculosis L-aspartate α-decarboxylase using nuclear magnetic resonance (1H NMR)

PloS one, 2012-09, Vol.7 (9), p.e45947

2012

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Chemoinformatic identification of novel inhibitors against Mycobacterium tuberculosis L-aspartate α-decarboxylase

PloS one, 2012-03, Vol.7 (3), p.e33521-e33521

2012

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Identification and molecular characterization of human antibody fragments specific for dengue NS5 protein

Virus research, 2014-01, Vol.179, p.225-230

2014

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Hibiscus chlorotic ringspot virus coat protein is essential for cell-to-cell and long-distance movement but not for viral RNA replication

PloS one, 2014-11, Vol.9 (11), p.e113347-e113347

2014

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Interaction of Mycobacterium tuberculosis RshA and SigH is mediated by salt bridges

PloS one, 2012-08, Vol.7 (8), p.e43676

2012

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Happy Marriages among Biophysical Techniques

Biophysical journal, 2013-01, Vol.104 (2), p.184a-184a

Swaminathan, Kunchithapadam

2013

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Structural analysis uncovers a role for redox in regulating FKBP13, an immunophilin of the chloroplast thylakoid lumen

Proceedings of the National Academy of Sciences - PNAS, 2004-09, Vol.101 (38), p.13945-13950

2004

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Lack of TNFα expression protects anaplastic lymphoma kinase-positive T-cell lymphoma (ALK+ TCL) cells from apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (37), p.15843-15848

2009

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A HEX-1 crystal lattice required for Woronin body function in Neurospora crassa

Nature structural & molecular biology, 2003-04, Vol.10 (4), p.264-270

2003

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Modifying the substrate specificity of Carcinoscorpius rotundicauda serine protease inhibitor domain 1 to target thrombin

PloS one, 2010-12, Vol.5 (12), p.e15258

2010

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A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy

A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication

Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)

Engineering of serine protease for improved thermostability and catalytic activity using rational design

Investigating the molecular basis of Siah1 and Siah2 E3 ubiquitin ligase substrate specificity

Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis

Crystal Structure of Arabidopsis Cyclophilin38 Reveals a Previously Uncharacterized Immunophilin Fold and a Possible Autoinhibitory Mechanism

Crystal structure of the PAC1R extracellular domain unifies a consensus fold for hormone recognition by class B G-protein coupled receptors

Avathrin: a novel thrombin inhibitor derived from a multicopy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum

Structure of a diguanylate cyclase from Thermotoga maritima: insights into activation, feedback inhibition and thermostability

Structural and Functional Studies of trans-Encoded HLA-DQ2.3 (DQA103:01/DQB102:01) Protein Molecule

H2O2 inhibits ABA-signaling protein phosphatase HAB1

α-Glucan pathway as a novel Mtb drug target: structural insights and cues for polypharmcological targeting of GlgB and GlgE

Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - experimental validation in human breast and colon cancer

Crystal structure of thrombin in complex with S-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors

Validation of drug-like inhibitors against Mycobacterium tuberculosis L-aspartate α-decarboxylase using nuclear magnetic resonance (1H NMR)

Chemoinformatic identification of novel inhibitors against Mycobacterium tuberculosis L-aspartate α-decarboxylase

Identification and molecular characterization of human antibody fragments specific for dengue NS5 protein

Hibiscus chlorotic ringspot virus coat protein is essential for cell-to-cell and long-distance movement but not for viral RNA replication

Interaction of Mycobacterium tuberculosis RshA and SigH is mediated by salt bridges

Happy Marriages among Biophysical Techniques

Structural analysis uncovers a role for redox in regulating FKBP13, an immunophilin of the chloroplast thylakoid lumen

Lack of TNFα expression protects anaplastic lymphoma kinase-positive T-cell lymphoma (ALK+ TCL) cells from apoptosis

A HEX-1 crystal lattice required for Woronin body function in Neurospora crassa

Modifying the substrate specificity of Carcinoscorpius rotundicauda serine protease inhibitor domain 1 to target thrombin

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