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Induction of AMPK activation by N,N'-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers

PloS one, 2019-03, Vol.14 (3), p.e0209392

2019

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Epigenetic Regulation of Wnt Signaling by Carboxamide-Substituted Benzhydryl Amines that Function as Histone Demethylase Inhibitors

iScience, 2020-12, Vol.23 (12), p.101795-101795, Article 101795

2020

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A crystal structure of coil 1B of vimentin in the filamentous form provides a model of a high‐order assembly of a vimentin filament

The FEBS journal, 2018-08, Vol.285 (15), p.2888-2899

2018

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One-Pot Synthesis of B‑Ring Ortho-Hydroxylated Sappanin-Type Homoisoflavonoids

Journal of organic chemistry, 2019-06, Vol.84 (11), p.7138-7147

2019

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Arylquins target vimentin to trigger Par-4 secretion for tumor cell apoptosis

Nature chemical biology, 2014-11, Vol.10 (11), p.924-926

2014

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An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors

Journal of medicinal chemistry, 2019-12, Vol.62 (24), p.11348-11358

2019

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Potent Synergistic Effect on C-Myc-Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor

Molecular cancer therapeutics, 2021-10, Vol.20 (10), p.1893-1903

2021

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Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents

Journal of medicinal chemistry, 2021-08, Vol.64 (16), p.12152-12162

2021

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Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)

Organic & biomolecular chemistry, 2017-09, Vol.15 (36), p.7623-7629

2017

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Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

Scientific reports, 2019-04, Vol.9 (1), p.6439-6439, Article 6439

2019

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2′,6′-Dihalostyrylanilines, Pyridines, and Pyrimidines for the Inhibition of the Catalytic Subunit of Methionine S‑Adenosyltransferase‑2

Journal of medicinal chemistry, 2014-07, Vol.57 (14), p.6083-6091

2014

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Pictet-Spengler condensations using 4-(2-aminoethyl)coumarins

New journal of chemistry, 2020-08, Vol.44 (31), p.13415-13429

2020

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Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells

Molecular cancer therapeutics, 2017-05, Vol.16 (5), p.831-837

2017

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Chemoselective synthesis of 3-trifluoromethylpyrazole-deoxybenzoin hybrids

Journal of fluorine chemistry, 2021-02, Vol.242, p.109698, Article 109698

2021

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Abstract 1222: Fluorinated N, N-diarylureas treatment as effective strategy to target colorectal cancer stem cells

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1222-1222

2016

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Analysis of trans-2,6-difluoro-4′-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite identification and pharmacokinetics

Analytical and bioanalytical chemistry, 2015-09, Vol.407 (24), p.7319-7332

2015

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A Direct Synthesis of 2‐(ω‐Carboxyalkyl)isoflavones from ortho‐Hydroxylated Deoxybenzoins

European journal of organic chemistry, 2018-10, Vol.2018 (39), p.5460-5463

2018

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Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals

Organic & biomolecular chemistry, 2015-01, Vol.13 (4), p.1053-1067

2015

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Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents

Organic & biomolecular chemistry, 2015-12, Vol.13 (46), p.11292-11301

2015

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Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin

Organic & biomolecular chemistry, 2016-01, Vol.14 (1), p.74-84

2016

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Bis(N-amidinohydrazones) and N-(amidino)-N′-aryl-bishydrazones: New classes of antibacterial/antifungal agents

Bioorganic & medicinal chemistry, 2017-01, Vol.25 (1), p.58-66

2017

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N-Aryl benzenesulfonamide inhibitors of [3H]-thymidine incorporation and β-catenin signaling in human hepatocyte-derived Huh-7 carcinoma cells

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (18), p.3897-3899

2015

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Crizotinib induces Par-4 secretion from normal cells and GRP78 expression on the cancer cell surface for selective tumor growth inhibition

American journal of cancer research, 2023-01, Vol.13 (3), p.976-991

2023

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Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases

ChemMedChem, 2016-03, Vol.11 (6), p.600-611

2016

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Development of 6H-chromeno[3,4-c]pyrido[3′,2′:4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 secretagogues

Tetrahedron letters, 2015-06, Vol.56 (23), p.3382-3384

2015

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Induction of AMPK activation by N,N'-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers

Epigenetic Regulation of Wnt Signaling by Carboxamide-Substituted Benzhydryl Amines that Function as Histone Demethylase Inhibitors

A crystal structure of coil 1B of vimentin in the filamentous form provides a model of a high‐order assembly of a vimentin filament

One-Pot Synthesis of B‑Ring Ortho-Hydroxylated Sappanin-Type Homoisoflavonoids

Arylquins target vimentin to trigger Par-4 secretion for tumor cell apoptosis

An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors

Potent Synergistic Effect on C-Myc-Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor

Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents

Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)

Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

2′,6′-Dihalostyrylanilines, Pyridines, and Pyrimidines for the Inhibition of the Catalytic Subunit of Methionine S‑Adenosyltransferase‑2

Pictet-Spengler condensations using 4-(2-aminoethyl)coumarins

Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells

Chemoselective synthesis of 3-trifluoromethylpyrazole-deoxybenzoin hybrids

Abstract 1222: Fluorinated N, N-diarylureas treatment as effective strategy to target colorectal cancer stem cells

Analysis of trans-2,6-difluoro-4′-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite identification and pharmacokinetics

A Direct Synthesis of 2‐(ω‐Carboxyalkyl)isoflavones from ortho‐Hydroxylated Deoxybenzoins

Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals

Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents

Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin

Bis(N-amidinohydrazones) and N-(amidino)-N′-aryl-bishydrazones: New classes of antibacterial/antifungal agents

N-Aryl benzenesulfonamide inhibitors of [3H]-thymidine incorporation and β-catenin signaling in human hepatocyte-derived Huh-7 carcinoma cells

Crizotinib induces Par-4 secretion from normal cells and GRP78 expression on the cancer cell surface for selective tumor growth inhibition

Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases

Development of 6H-chromeno[3,4-c]pyrido[3′,2′:4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 secretagogues

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