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Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA+ Lon Protease

Molecular cell, 2013-01, Vol.49 (1), p.121-132

2013

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Multitasking in the mitochondrion by the ATP-dependent Lon protease

Biochimica et biophysica acta, 2012-01, Vol.1823 (1), p.56-66

2012

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Mitochondrial LonP1 protects cardiomyocytes from ischemia/reperfusion injury in vivo

Journal of molecular and cellular cardiology, 2019-03, Vol.128, p.38-50

2019

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CODAS Syndrome Is Associated with Mutations of LONP1, Encoding Mitochondrial AAA+ Lon Protease

American journal of human genetics, 2015-01, Vol.96 (1), p.121-135

2015

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Functional mechanics of the ATP-dependent Lon protease- lessons from endogenous protein and synthetic peptide substrates

Biochimica et biophysica acta, 2008-05, Vol.1784 (5), p.727-735

2008

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The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives

Blood, 2012-04, Vol.119 (14), p.3321-3329

2012

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Heat shock protein 22 (Hsp22) regulates oxidative phosphorylation upon its mitochondrial translocation with the inducible nitric oxide synthase in mammalian heart

PloS one, 2015-03, Vol.10 (3), p.e0119537-e0119537

2015

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Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM

Bioscience reports, 2017-06, Vol.37 (3)

2017

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Turnover of Mitochondrial Steroidogenic Acute Regulatory (StAR) Protein by Lon Protease: The Unexpected Effect of Proteasome Inhibitors

Molecular endocrinology (Baltimore, Md.), 2007-09, Vol.21 (9), p.2164-2177

2007

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Roles for the Human ATP-dependent Lon Protease in Mitochondrial DNA Maintenance

The Journal of biological chemistry, 2007-06, Vol.282 (24), p.17363-17374

2007

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LonP1 Links Mitochondria-ER Interaction to Regulate Heart Function

Research (Washington), 2023, Vol.6, p.0175-0175

2023

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DNA and RNA Binding by the Mitochondrial Lon Protease Is Regulated by Nucleotide and Protein Substrate

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.13902-13910

2004

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Cell stress management by the mitochondrial LonP1 protease – Insights into mitigating developmental, oncogenic and cardiac stress

Mitochondrion, 2020-03, Vol.51, p.46-61

2020

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Powering down the mitochondrial LonP1 protease: a novel strategy for anticancer therapeutics

Expert opinion on therapeutic targets, 2024, Vol.28 (1-2), p.9-15

2024

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HSP60 Takes a Hit: Inhibition of Mitochondrial Protein Folding

Cell chemical biology, 2017-05, Vol.24 (5), p.543-545

2017

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The Chaperones MPP11 and Hsp70L1 Form the Mammalian Ribosome-Associated Complex

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (29), p.10064-10069

2005

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Pharmacology, Pharmacotherapy, and Pharmacopolicy Through an Evidence-Based Medicine: A Novel Approach for First-Year Medical Students

MedEdPORTAL, 2020-07, Vol.16

2020

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Structure of the catalytic domain of the human mitochondrial Lon protease: Proposed relation of oligomer formation and activity

Protein science, 2010-05, Vol.19 (5), p.987-999

2010

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Tid1 Isoforms Are Mitochondrial DnaJ-like Chaperones with Unique Carboxyl Termini That Determine Cytosolic Fate

The Journal of biological chemistry, 2006-05, Vol.281 (19), p.13150-13158

2006

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Cleavage Site Selection within a Folded Substrate by the ATP-dependent Lon Protease

The Journal of biological chemistry, 2005-07, Vol.280 (26), p.25103-25110

2005

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Inhibition of mitochondrial LonP1 protease by allosteric blockade of ATP binding and hydrolysis via CDDO and its derivatives

The Journal of biological chemistry, 2022-03, Vol.298 (3), p.101719, Article 101719

2022

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Differential regulation of full-length genome and a single-stranded 7S DNA along the cell cycle in human mitochondria

Nucleic acids research, 2010-10, Vol.38 (19), p.6466

2010

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Effect of densely ionizing radiation on cardiomyocyte differentiation from human‐induced pluripotent stem cells

Physiological reports, 2017-08, Vol.5 (15), p.n/a

2017

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Mitochondrial LON protease-dependent degradation of cytochrome c oxidase subunits under hypoxia and myocardial ischemia

Biochimica et biophysica acta. Bioenergetics, 2017-07, Vol.1858 (7), p.519-528

2017

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Bi-allelic mutations of LONP1 encoding the mitochondrial LonP1 protease cause pyruvate dehydrogenase deficiency and profound neurodegeneration with progressive cerebellar atrophy

Human molecular genetics, 2019-01, Vol.28 (2), p.290-306

2019

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Phosphorylation of Human TFAM in Mitochondria Impairs DNA Binding and Promotes Degradation by the AAA+ Lon Protease

Multitasking in the mitochondrion by the ATP-dependent Lon protease

Mitochondrial LonP1 protects cardiomyocytes from ischemia/reperfusion injury in vivo

CODAS Syndrome Is Associated with Mutations of LONP1, Encoding Mitochondrial AAA+ Lon Protease

Functional mechanics of the ATP-dependent Lon protease- lessons from endogenous protein and synthetic peptide substrates

The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives

Heat shock protein 22 (Hsp22) regulates oxidative phosphorylation upon its mitochondrial translocation with the inducible nitric oxide synthase in mammalian heart

Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM

Turnover of Mitochondrial Steroidogenic Acute Regulatory (StAR) Protein by Lon Protease: The Unexpected Effect of Proteasome Inhibitors

Roles for the Human ATP-dependent Lon Protease in Mitochondrial DNA Maintenance

LonP1 Links Mitochondria-ER Interaction to Regulate Heart Function

DNA and RNA Binding by the Mitochondrial Lon Protease Is Regulated by Nucleotide and Protein Substrate

Cell stress management by the mitochondrial LonP1 protease – Insights into mitigating developmental, oncogenic and cardiac stress

Powering down the mitochondrial LonP1 protease: a novel strategy for anticancer therapeutics

HSP60 Takes a Hit: Inhibition of Mitochondrial Protein Folding

The Chaperones MPP11 and Hsp70L1 Form the Mammalian Ribosome-Associated Complex

Pharmacology, Pharmacotherapy, and Pharmacopolicy Through an Evidence-Based Medicine: A Novel Approach for First-Year Medical Students

Structure of the catalytic domain of the human mitochondrial Lon protease: Proposed relation of oligomer formation and activity

Tid1 Isoforms Are Mitochondrial DnaJ-like Chaperones with Unique Carboxyl Termini That Determine Cytosolic Fate

Cleavage Site Selection within a Folded Substrate by the ATP-dependent Lon Protease

Inhibition of mitochondrial LonP1 protease by allosteric blockade of ATP binding and hydrolysis via CDDO and its derivatives

Differential regulation of full-length genome and a single-stranded 7S DNA along the cell cycle in human mitochondria

Effect of densely ionizing radiation on cardiomyocyte differentiation from human‐induced pluripotent stem cells

Mitochondrial LON protease-dependent degradation of cytochrome c oxidase subunits under hypoxia and myocardial ischemia

Bi-allelic mutations of LONP1 encoding the mitochondrial LonP1 protease cause pyruvate dehydrogenase deficiency and profound neurodegeneration with progressive cerebellar atrophy

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