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Redefining the architecture of ferlin proteins: Insights into multi-domain protein structure and function

PloS one, 2022-07, Vol.17 (7), p.e0270188-e0270188

2022

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Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder

Neuron (Cambridge, Mass.), 2020-07, Vol.107 (1), p.52-64.e7

2020

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Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY)

Biochemical journal, 2020-11, Vol.477 (21), p.4149-4165

2020

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A DNA aptamer reveals an allosteric site for inhibition in metallo-β-lactamases

PloS one, 2019-04, Vol.14 (4), p.e0214440

2019

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Ferlins: Regulators of Vesicle Fusion for Auditory Neurotransmission, Receptor Trafficking and Membrane Repair

Traffic (Copenhagen, Denmark), 2012-02, Vol.13 (2), p.185-194

2012

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Drosophila studies support a role for a presynaptic synaptotagmin mutation in a human congenital myasthenic syndrome

PloS one, 2017-09, Vol.12 (9), p.e0184817-e0184817

2017

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Maturation of the functional mouse CRES amyloid from globular form

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (28), p.16363-16372

2020

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The mouse epididymal amyloid matrix is a mammalian counterpart of a bacterial biofilm

iScience, 2024-06, Vol.27 (6), p.110152, Article 110152

2024

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Alternate Splicing of Dysferlin C2A Confers Ca2+-Dependent and Ca2+-Independent Binding for Membrane Repair

Structure (London), 2014-01, Vol.22 (1), p.104-115

2014

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Supertertiary structure of the synaptic MAGuK scaffold proteins is conserved

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (39), p.15775-15780

2012

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A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion

eLife, 2017-09, Vol.6

2017

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Current progress of adeno-associated-virus-based therapy for the treatment of cystic fibrosis in humans

The Southwest respiratory and critical care chronicles, 2018-04, Vol.6 (23), p.1-3

Sutton, R. Bryan

2018

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Conserved Structural Features of the Synaptic Fusion Complex: SNARE Proteins Reclassified as Q- and R-SNAREs

Proceedings of the National Academy of Sciences - PNAS, 1998-12, Vol.95 (26), p.15781-15786

1998

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Structural features of Dnase1L3 responsible for serum antigen clearance

Communications biology, 2022-08, Vol.5 (1), p.825-825, Article 825

2022

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Expression of Hsp90 chaperome proteins in human tumor tissue

International journal of biological macromolecules, 2009-10, Vol.45 (3), p.310-314

2009

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Dnase1 Family in Autoimmunity

Encyclopedia (Basel, Switzerland), 2021-07, Vol.1 (3), p.527-541

2021

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A chimeric anti-vascularization immunomodulator prevents high-risk corneal transplantation rejection via ex vivo gene therapy

Molecular therapy, 2024-09

2024

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Viral Transfer of Mini-Otoferlins Partially Restores the Fast Component of Exocytosis and Uncovers Ultrafast Endocytosis in Auditory Hair Cells of Otoferlin Knock-Out Mice

The Journal of neuroscience, 2019-05, Vol.39 (18), p.3394-3411

2019

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Temperature-dependent RNA editing in octopus extensively recodes the neural proteome

Cell, 2023-06, Vol.186 (12), p.2544-2555.e13

2023

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Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

Nature (London), 1998-09, Vol.395 (6700), p.347-353

1998

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Negative coupling as a mechanism for signal propagation between C2 domains of synaptotagmin I

PloS one, 2012-10, Vol.7 (10), p.e46748-e46748

2012

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Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice

Journal of leukocyte biology, 2023-11, Vol.114 (6), p.547-556

2023

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Structure-Based Designed Nano-Dysferlin Significantly Improves Dysferlinopathy in BLA/J Mice

Molecular therapy, 2017-09, Vol.25 (9), p.2150-2162

2017

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A unique C2 domain at the C terminus of Munc13 promotes synaptic vesicle priming

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (11), p.1

2021

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Redefining the architecture of ferlin proteins: Insights into multi-domain protein structure and function

Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder

Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY)

A DNA aptamer reveals an allosteric site for inhibition in metallo-β-lactamases

Ferlins: Regulators of Vesicle Fusion for Auditory Neurotransmission, Receptor Trafficking and Membrane Repair

Drosophila studies support a role for a presynaptic synaptotagmin mutation in a human congenital myasthenic syndrome

Maturation of the functional mouse CRES amyloid from globular form

The mouse epididymal amyloid matrix is a mammalian counterpart of a bacterial biofilm

Alternate Splicing of Dysferlin C2A Confers Ca2+-Dependent and Ca2+-Independent Binding for Membrane Repair

Supertertiary structure of the synaptic MAGuK scaffold proteins is conserved

A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion

Current progress of adeno-associated-virus-based therapy for the treatment of cystic fibrosis in humans

Conserved Structural Features of the Synaptic Fusion Complex: SNARE Proteins Reclassified as Q- and R-SNAREs

Structural features of Dnase1L3 responsible for serum antigen clearance

Expression of Hsp90 chaperome proteins in human tumor tissue

Dnase1 Family in Autoimmunity

Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses

A chimeric anti-vascularization immunomodulator prevents high-risk corneal transplantation rejection via ex vivo gene therapy

Viral Transfer of Mini-Otoferlins Partially Restores the Fast Component of Exocytosis and Uncovers Ultrafast Endocytosis in Auditory Hair Cells of Otoferlin Knock-Out Mice

Temperature-dependent RNA editing in octopus extensively recodes the neural proteome

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

Negative coupling as a mechanism for signal propagation between C2 domains of synaptotagmin I

Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice

Structure-Based Designed Nano-Dysferlin Significantly Improves Dysferlinopathy in BLA/J Mice

A unique C2 domain at the C terminus of Munc13 promotes synaptic vesicle priming

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