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Nalfurafine, a G-Protein-Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics

Hypertension (Dallas, Tex. 1979), 2022-02, Vol.79 (2), p.379-390

2022

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Difelikefalin, a peripherally restricted KOR (kappa opioid receptor) agonist, produces diuresis through a central KOR pathway

Pharmacological research, 2022-11, Vol.185, p.106470-106470, Article 106470

2022

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Cardiovascular and renal effects of novel nonpeptide nociceptin opioid peptide receptor agonists

British journal of pharmacology, 2022-01, Vol.179 (2), p.287-300

2022

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Downregulation of Brain Gα12 Attenuates Angiotensin II-Dependent Hypertension

American journal of hypertension, 2020-02, Vol.33 (2), p.198-204

2020

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Interactive effects of (±)-trans-U50488 and its stereoisomers with cannabinoids

Pharmacology, biochemistry and behavior, 2021-08, Vol.207, p.173218-173218, Article 173218

2021

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3326 Radiofrequency Renal Denervation Prevents Further Progression of Hypertension and Decreases Renal Medullary Fibrosis in One-year-old Spontaneously Hypertensive Rats (SHR)

Journal of clinical and translational science, 2019-03, Vol.3 (s1), p.19-19

2019

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Difelikefalin, a peripherally restricted kappa opioid receptor agonist, evokes diuresis through a central kappa opioid receptor pathway

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Abstract 13956: Nalfurafine, an Orally Active, G Protein-Biased Kappa Opioid Receptor Agonist, Increases the Diuretic Response to Loop and Thiazide Diuretics and Limits Electrolyte Losses

Circulation (New York, N.Y.), 2021-11, Vol.144 (Suppl_1)

2021

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Nalfurafine Combined with Standard‐of‐Care Diuretics Increases Diuresis and Limits Electrolyte Losses

The FASEB journal, 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.02447

2021

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Nalfurafine, a G protein-biased kappa opioid receptor agonist, enhances the diuretic response and limits electrolyte losses to standard-of-care diuretics

Hypertension (Dallas, Tex. 1979), 2021-12, Vol.79 (2), p.379-390

2021

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U50,488 Enantiomers Differentially Contribute to its Analgesic, Diuretic, and Discriminative Stimulus Effects

The FASEB journal, 2019-04, Vol.33 (S1), p.808.6-808.6

2019

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Cardiovascular and renal effects of novel non-peptide nociceptin opioid peptide (NOP) receptor agonists

British journal of pharmacology, 2021-12, Vol.179 (2), p.287-300

2021

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Leukocytic Thy‐1 Expression Differs in Kidney Cortex and Medulla in Spontaneously Hypertensive Rats

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Modulation of Renal Excretory Function by the Conformationally Restricted Enantiomeric κ‐Opioid Receptor Agonists: (+) U‐50,488 and (−) U‐50,488

The FASEB journal, 2019-04, Vol.33 (S1), p.678.2-678.2

2019

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Radiofrequency Renal Denervation Prevents Further Progression of Hypertension and Decreases Renal Medullary Fibrosis in One‐year‐old Spontaneously Hypertensive Rats (SHR)

The FASEB journal, 2019-04, Vol.33 (S1), p.749.7-749.7

2019

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Mouse model systems of autism spectrum disorder: Replicability and informatics signature

Genes, brain and behavior, 2020-09, Vol.19 (7), p.e12676-n/a

2020

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Cognitive Training at a Young Age Attenuates Deficits in the zQ175 Mouse Model of HD

Frontiers in behavioral neuroscience, 2016-01, Vol.9, p.361-361

2016

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Deficits in a Simple Visual Go/No-go Discrimination Task in Two Mouse Models of Huntington's Disease

PLoS currents, 2013-11, Vol.5

2013

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A mixed fixed ratio/progressive ratio procedure reveals an apathy phenotype in the BAC HD and the z_Q175 KI mouse models of Huntington's disease

PLoS currents, 2012-04, Vol.4, p.e4f972cffe82c0-e4f972cffe82c0

2012

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Temporal Control Deficits in Murine Models of Huntington’s Disease

International journal of comparative psychology, 2015, Vol.28

2015

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HD mouse models reveal clear deficits in learning to perform a simple instrumental response

PLoS currents, 2011-11, Vol.3, p.RRN1282-RRN1282

2011

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Difelikefalin, a Peripherally Restricted KOR (Kappa Opioid Receptor) Agonist, Produces Diuresis Through a Central KOR Pathway

SSRN Electronic Journal

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Nalfurafine, a G-Protein-Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics

Difelikefalin, a peripherally restricted KOR (kappa opioid receptor) agonist, produces diuresis through a central KOR pathway

Cardiovascular and renal effects of novel nonpeptide nociceptin opioid peptide receptor agonists

Downregulation of Brain Gα12 Attenuates Angiotensin II-Dependent Hypertension

Interactive effects of (±)-trans-U50488 and its stereoisomers with cannabinoids

3326 Radiofrequency Renal Denervation Prevents Further Progression of Hypertension and Decreases Renal Medullary Fibrosis in One-year-old Spontaneously Hypertensive Rats (SHR)

Difelikefalin, a peripherally restricted kappa opioid receptor agonist, evokes diuresis through a central kappa opioid receptor pathway

Abstract 13956: Nalfurafine, an Orally Active, G Protein-Biased Kappa Opioid Receptor Agonist, Increases the Diuretic Response to Loop and Thiazide Diuretics and Limits Electrolyte Losses

Nalfurafine Combined with Standard‐of‐Care Diuretics Increases Diuresis and Limits Electrolyte Losses

Nalfurafine, a G protein-biased kappa opioid receptor agonist, enhances the diuretic response and limits electrolyte losses to standard-of-care diuretics

U50,488 Enantiomers Differentially Contribute to its Analgesic, Diuretic, and Discriminative Stimulus Effects

Cardiovascular and renal effects of novel non-peptide nociceptin opioid peptide (NOP) receptor agonists

Leukocytic Thy‐1 Expression Differs in Kidney Cortex and Medulla in Spontaneously Hypertensive Rats

Modulation of Renal Excretory Function by the Conformationally Restricted Enantiomeric κ‐Opioid Receptor Agonists: (+) U‐50,488 and (−) U‐50,488

Radiofrequency Renal Denervation Prevents Further Progression of Hypertension and Decreases Renal Medullary Fibrosis in One‐year‐old Spontaneously Hypertensive Rats (SHR)

Mouse model systems of autism spectrum disorder: Replicability and informatics signature

Cognitive Training at a Young Age Attenuates Deficits in the zQ175 Mouse Model of HD

Deficits in a Simple Visual Go/No-go Discrimination Task in Two Mouse Models of Huntington's Disease

A mixed fixed ratio/progressive ratio procedure reveals an apathy phenotype in the BAC HD and the z_Q175 KI mouse models of Huntington's disease

Temporal Control Deficits in Murine Models of Huntington’s Disease

HD mouse models reveal clear deficits in learning to perform a simple instrumental response

Difelikefalin, a Peripherally Restricted KOR (Kappa Opioid Receptor) Agonist, Produces Diuresis Through a Central KOR Pathway

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