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SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

Blood, 2013-08, Vol.122 (8), p.1455-1463

2013

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Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates

The Journal of biological chemistry, 2006-04, Vol.281 (15), p.10540-10547

2006

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Antibody-Dependent Cell-Mediated Cytotoxicity Overcomes NK Cell Resistance in MLL-Rearranged Leukemia Expressing Inhibitory KIR Ligands but Not Activating Ligands

Clinical cancer research, 2012-11, Vol.18 (22), p.6296-6305

2012

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Sclerostin Inhibition of Wnt-3a-induced C3H10T1/2 Cell Differentiation Is Indirect and Mediated by Bone Morphogenetic Proteins

The Journal of biological chemistry, 2005-01, Vol.280 (4), p.2498-2502

2005

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Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

The EMBO journal, 2003-12, Vol.22 (23), p.6267-6276

2003

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Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation

Bone (New York, N.Y.), 2004-10, Vol.35 (4), p.828-835

2004

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Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas

Blood, 2009-04, Vol.113 (18), p.4352-4361

2009

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Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia

Molecular cancer therapeutics, 2018-02, Vol.17 (2), p.554-564

2018

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Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts

Bone (New York, N.Y.), 2004-08, Vol.35 (2), p.448-454

2004

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Anti-leukemic activity of Lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia

mAbs, 2009-09, Vol.1 (5), p.481-490

2009

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5-Azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia

mAbs, 2010-07, Vol.2 (4), p.440-448

2010

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The Biological Activities of 1α,25-Dihydroxyvitamin D3 and Its Synthetic Analog 1α,25-Dihydroxy-16-ene-vitamin D3 in Normal Human Osteoblastic Cells and Human Osteosarcoma SaOS-2 Cells Are Modulated by 17-β Estradiol and Dependent on Stage of Differentiation

Biological and Pharmaceutical Bulletin, 2001, Vol.24(3), pp.242-248

2001

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IL-6 as a drug discovery target

Drug discovery today, 1998-05, Vol.3 (5), p.202-213

1998

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SP500263, a novel SERM, blocks osteoclastogenesis in a human bone cell model: role of IL-6 and GM-CSF

Cytokine (Philadelphia, Pa.), 2003-07, Vol.23 (1), p.1-14

2003

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A sugar engineered non-fucosylated anti-CD40 antibody, SEA-CD40, with enhanced immune stimulatory activity alone and in combination with immune checkpoint inhibitors

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.3074-3074

2015

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The biological activities of 1alpha,25-dihydroxyvitamin D3 and its synthetic analog 1alpha,25-dihydroxy-16-ene-vitamin D3 in normal human osteoblastic cells and human osteosarcoma SaOS-2 cells are modulated by 17-beta estradiol and dependent on stage of differentiation

Biological & pharmaceutical bulletin, 2001-03, Vol.24 (3), p.242-248

2001

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Effects of SP500263, a novel, potent antiestrogen, on breast cancer cells and in xenograft models

Cancer research (Chicago, Ill.), 2002-03, Vol.62 (5), p.1439-1442

2002

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5-azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia

mAbs, 2010-01, Vol.2 (4), p.440-448

2010

Volltextzugriff (PDF)

Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts : Fractures in osteoporosis

Bone (New York, N.Y.), 2004, Vol.35 (2), p.448-454

2004

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Differential response of estrogen receptors alpha and beta to SP500263, a novel potent selective estrogen receptor modulator

Molecular pharmacology, 2002-03, Vol.61 (3), p.562-568

2002

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Differential Response of Estrogen Receptors Î± and Î² to SP500263, a Novel Potent Selective Estrogen Receptor Modulator

Molecular pharmacology, 2002-03, Vol.61 (3), p.562

2002

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17β-estradiol and parathyroid hormone potentiate each other's stimulatory effects on alkaline phosphatase activity in SaOS-2 cells in a differentiation-dependent manner

Endocrinology (Philadelphia), 1994, Vol.134 (2), p.614-620

1994

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The Biological Activities of 1[alpha],25-Dihydroxyvitamin D3 and Its Synthetic Analog 1[alpha],25-Dihydroxy-16-ene-vitamin D3 in Normal Human Osteoblastic Cells and Human Osteosarcoma SaOS-2 Cells Are Modulated by 17-[beta] Estradiol and Dependent on Stage of Differentiation

Biological & pharmaceutical bulletin, 2001-03, Vol.24 (3), p.242

2001

Volltextzugriff (PDF)

The biological activities of 1α, 25-dihydroxyvitamin D3and its synthetic analog 1α, 25-dihydroxy-16-ene-vitamin D3 in normal human osteoblastic cells and human osteosarcoma SaOS-2 cells are modulated by 17-β estradiol and dependent on stage of differentiation

Biological & pharmaceutical bulletin, 2001, Vol.24 (3), p.242-248

2001

Volltextzugriff (PDF)

Reduction of vitamin D hormone receptor mRNA levels in Alzheimer as compared to Huntington hippocampus: correlation with calbindin-28k mRNA levels

Brain research. Molecular brain research., 1992-04, Vol.13 (3), p.239-250

1992

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SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates

Antibody-Dependent Cell-Mediated Cytotoxicity Overcomes NK Cell Resistance in MLL-Rearranged Leukemia Expressing Inhibitory KIR Ligands but Not Activating Ligands

Sclerostin Inhibition of Wnt-3a-induced C3H10T1/2 Cell Differentiation Is Indirect and Mediated by Bone Morphogenetic Proteins

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation

Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas

Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia

Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts

Anti-leukemic activity of Lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia

5-Azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia

The Biological Activities of 1α,25-Dihydroxyvitamin D3 and Its Synthetic Analog 1α,25-Dihydroxy-16-ene-vitamin D3 in Normal Human Osteoblastic Cells and Human Osteosarcoma SaOS-2 Cells Are Modulated by 17-β Estradiol and Dependent on Stage of Differentiation

IL-6 as a drug discovery target

SP500263, a novel SERM, blocks osteoclastogenesis in a human bone cell model: role of IL-6 and GM-CSF

A sugar engineered non-fucosylated anti-CD40 antibody, SEA-CD40, with enhanced immune stimulatory activity alone and in combination with immune checkpoint inhibitors

The biological activities of 1alpha,25-dihydroxyvitamin D3 and its synthetic analog 1alpha,25-dihydroxy-16-ene-vitamin D3 in normal human osteoblastic cells and human osteosarcoma SaOS-2 cells are modulated by 17-beta estradiol and dependent on stage of differentiation

Effects of SP500263, a novel, potent antiestrogen, on breast cancer cells and in xenograft models

5-azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia

Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts : Fractures in osteoporosis

Differential response of estrogen receptors alpha and beta to SP500263, a novel potent selective estrogen receptor modulator

Differential Response of Estrogen Receptors Î± and Î² to SP500263, a Novel Potent Selective Estrogen Receptor Modulator

17β-estradiol and parathyroid hormone potentiate each other's stimulatory effects on alkaline phosphatase activity in SaOS-2 cells in a differentiation-dependent manner

The Biological Activities of 1[alpha],25-Dihydroxyvitamin D3 and Its Synthetic Analog 1[alpha],25-Dihydroxy-16-ene-vitamin D3 in Normal Human Osteoblastic Cells and Human Osteosarcoma SaOS-2 Cells Are Modulated by 17-[beta] Estradiol and Dependent on Stage of Differentiation

The biological activities of 1α, 25-dihydroxyvitamin D3and its synthetic analog 1α, 25-dihydroxy-16-ene-vitamin D3 in normal human osteoblastic cells and human osteosarcoma SaOS-2 cells are modulated by 17-β estradiol and dependent on stage of differentiation

Reduction of vitamin D hormone receptor mRNA levels in Alzheimer as compared to Huntington hippocampus: correlation with calbindin-28k mRNA levels

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