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Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval--A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity

PloS one, 2015-08, Vol.10 (8), p.e0136369-e0136369

2015

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Celecoxib-tramadol co-crystal: A Randomized 4-Way Crossover Comparative Bioavailability Study

Clinical therapeutics, 2021-06, Vol.43 (6), p.1051-1065

2021

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Efficacy of a Novel Sigma-1 Receptor Antagonist for Oxaliplatin-Induced Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Clinical Trial

Neurotherapeutics, 2018-01, Vol.15 (1), p.178-189

2018

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Co-crystal of tramadol-celecoxib (CTC) for acute moderate-to-severe pain

Current medical research and opinion, 2024-03, Vol.40 (3), p.455-468

2024

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Single‐dose pharmacokinetics of co‐crystal of tramadol–celecoxib: Results of a four‐way randomized open‐label phase I clinical trial in healthy subjects

British journal of clinical pharmacology, 2017-12, Vol.83 (12), p.2718-2728

2017

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Safety, tolerability and pharmacokinetics of single and multiple doses of a novel sigma‐1 receptor antagonist in three randomized phase I studies

British journal of clinical pharmacology, 2013-01, Vol.75 (1), p.103-117

2013

Volltextzugriff (PDF)

Efficacy and safety of co‐crystal of tramadol‐celecoxib (CTC) in acute moderate‐to‐severe pain after abdominal hysterectomy: A randomized, double‐blind, phase 3 trial (STARDOM2)

European journal of pain, 2022-11, Vol.26 (10), p.2083-2096

2022

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A single-centre, open-label, controlled, randomized clinical trial to assess the preventive efficacy of a domperidone-based treatment programme against clinical canine leishmaniasis in a high prevalence area

Preventive veterinary medicine, 2014-07, Vol.115 (1-2), p.56-63

2014

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Efficacy of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: A Pooled Analysis of Data from Two Phase 3 Randomized Clinical Trials

Drugs in R&D, 2024-06, Vol.24 (2), p.239-252

2024

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Pharmacokinetics of multiple doses of co‐crystal of tramadol–celecoxib: findings from a four‐way randomized open‐label phase I clinical trial

British journal of clinical pharmacology, 2018-01, Vol.84 (1), p.64-78

2018

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Co-crystal of Tramadol-Celecoxib Versus Tramadol or Placebo for Acute Moderate-to-Severe Pain After Oral Surgery: Randomized, Double-Blind, Phase 3 Trial (STARDOM1)

Advances in therapy, 2024-03, Vol.41 (3), p.1025-1045

2024

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Effect of ketoprofen on pre-weaning piglet mortality on commercial farms

The veterinary journal (1997), 2014-09, Vol.201 (3), p.435-437

2014

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Celecoxib‐tramadol co‐crystal in patients with moderate‐to‐severe pain following bunionectomy with osteotomy: Secondary analyses by baseline pain intensity and use of rescue medication of a phase 3, randomized, double‐blind, factorial, active‐ and placebo‐controlled trial

Pain practice, 2024-07

2024

Volltextzugriff (PDF)

Co-crystal of Tramadol–Celecoxib in Patients with Moderate to Severe Acute Post-surgical Oral Pain: A Dose-Finding, Randomised, Double-Blind, Placebo- and Active-Controlled, Multicentre, Phase II Trial

Drugs in R&D, 2018-06, Vol.18 (2), p.137-148

2018

Volltextzugriff (PDF)

Cizolirtine Citrate, an Effective Treatment for Symptomatic Patients with Urinary Incontinence Secondary to Overactive Bladder: A Pilot Dose-Finding Study

European urology, 2009-07, Vol.56 (1), p.184-192

2009

Volltextzugriff (PDF)

Amphotericin B lipid complex versus meglumine antimoniate in the treatment of visceral leishmaniasis in patients infected with HIV: a randomized pilot study

Journal of antimicrobial chemotherapy, 2003-09, Vol.52 (3), p.464-468

2003

Volltextzugriff (PDF)

Cizolirtine Citrate, an Effective Treatment for Symptomatic Patients with Urinary Incontinence Secondary to Overactive Bladder: A Pilot Dose-Finding Study. Commentary

European urology, 2009, Vol.56 (1), p.184-192

2009

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How to ensure clinical trial sensitivity in psychotropic drug development: A case study

Clinical therapeutics, 2005-02, Vol.27 (2), p.252-254

2005

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Calcium Dobesilate for the Treatment of Erectile Dysfunction in Men with Diabetes Mellitus

Basic & clinical pharmacology & toxicology, 2008-10, Vol.103 (4), p.360-366

2008

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Comparison of cizolirtine citrate and metamizol sodium in the treatment of adult acute renal colic: A randomized, double-blind, clinical pilot study

Clinical therapeutics, 2004-07, Vol.26 (7), p.1061-1072

2004

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Treatment of type IIb familial combined hyperlipidemia with the combination pravastatin-piperazine sultosilate

European journal of pharmacology, 2004-08, Vol.496 (1), p.205-212

2004

Volltextzugriff (PDF)

Amphotericin B lipid complex versus meglumine antimoniate in thetreatment of visceral leishmaniasis in patients infected with HIV: arandomized pilotstudy

Journal of antimicrobial chemotherapy, 2003-09, Vol.52 (3), p.464-468

2003

Volltextzugriff (PDF)

Efficacy and safety of lesopitron in outpatients with generalized anxiety disorder

The Annals of pharmacotherapy, 2000-02, Vol.34 (2), p.147

2000

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Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval--A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity

Celecoxib-tramadol co-crystal: A Randomized 4-Way Crossover Comparative Bioavailability Study

Efficacy of a Novel Sigma-1 Receptor Antagonist for Oxaliplatin-Induced Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Clinical Trial

Co-crystal of tramadol-celecoxib (CTC) for acute moderate-to-severe pain

Single‐dose pharmacokinetics of co‐crystal of tramadol–celecoxib: Results of a four‐way randomized open‐label phase I clinical trial in healthy subjects

Safety, tolerability and pharmacokinetics of single and multiple doses of a novel sigma‐1 receptor antagonist in three randomized phase I studies

Efficacy and safety of co‐crystal of tramadol‐celecoxib (CTC) in acute moderate‐to‐severe pain after abdominal hysterectomy: A randomized, double‐blind, phase 3 trial (STARDOM2)

A single-centre, open-label, controlled, randomized clinical trial to assess the preventive efficacy of a domperidone-based treatment programme against clinical canine leishmaniasis in a high prevalence area

Efficacy of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: A Pooled Analysis of Data from Two Phase 3 Randomized Clinical Trials

Pharmacokinetics of multiple doses of co‐crystal of tramadol–celecoxib: findings from a four‐way randomized open‐label phase I clinical trial

Co-crystal of Tramadol-Celecoxib Versus Tramadol or Placebo for Acute Moderate-to-Severe Pain After Oral Surgery: Randomized, Double-Blind, Phase 3 Trial (STARDOM1)

Effect of ketoprofen on pre-weaning piglet mortality on commercial farms

Celecoxib‐tramadol co‐crystal in patients with moderate‐to‐severe pain following bunionectomy with osteotomy: Secondary analyses by baseline pain intensity and use of rescue medication of a phase 3, randomized, double‐blind, factorial, active‐ and placebo‐controlled trial

Celecoxib‐tramadol co‐crystal in patients with moderate‐to‐severe pain following bunionectomy with osteotomy: A phase 3, randomized, double‐blind, factorial, active‐ and placebo‐controlled trial

Co-crystal of Tramadol–Celecoxib in Patients with Moderate to Severe Acute Post-surgical Oral Pain: A Dose-Finding, Randomised, Double-Blind, Placebo- and Active-Controlled, Multicentre, Phase II Trial

Cizolirtine Citrate, an Effective Treatment for Symptomatic Patients with Urinary Incontinence Secondary to Overactive Bladder: A Pilot Dose-Finding Study

Amphotericin B lipid complex versus meglumine antimoniate in the treatment of visceral leishmaniasis in patients infected with HIV: a randomized pilot study

Cizolirtine Citrate, an Effective Treatment for Symptomatic Patients with Urinary Incontinence Secondary to Overactive Bladder: A Pilot Dose-Finding Study. Commentary

How to ensure clinical trial sensitivity in psychotropic drug development: A case study

Calcium Dobesilate for the Treatment of Erectile Dysfunction in Men with Diabetes Mellitus

Comparison of cizolirtine citrate and metamizol sodium in the treatment of adult acute renal colic: A randomized, double-blind, clinical pilot study

Treatment of type IIb familial combined hyperlipidemia with the combination pravastatin-piperazine sultosilate

Amphotericin B lipid complex versus meglumine antimoniate in thetreatment of visceral leishmaniasis in patients infected with HIV: arandomized pilotstudy

Efficacy and safety of lesopitron in outpatients with generalized anxiety disorder

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