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Whole-body and Whole-Organ Clearing and Imaging Techniques with Single-Cell Resolution: Toward Organism-Level Systems Biology in Mammals

Cell chemical biology, 2016-01, Vol.23 (1), p.137-157

2016

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Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

Nature protocols, 2015-11, Vol.10 (11), p.1709-1727

2015

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Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

Cell, 2014-04, Vol.157 (3), p.726-739

2014

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Whole-body imaging with single-cell resolution by tissue decolorization

Cell, 2014-11, Vol.159 (4), p.911-924

2014

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Color-Changing Fluorescent Barcode Based on Strand Displacement Reaction Enables Simple Multiplexed Labeling

Journal of the American Chemical Society, 2022-02, Vol.144 (4), p.1572-1579

2022

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Lipopolysaccharides and Cellular Senescence: Involvement in Atherosclerosis

International journal of molecular sciences, 2022-09, Vol.23 (19), p.11148

2022

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The oral hypoxia-inducible factor prolyl hydroxylase inhibitor enarodustat counteracts alterations in renal energy metabolism in the early stages of diabetic kidney disease

Kidney international, 2020-05, Vol.97 (5), p.934-950

2020

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Versatile whole-organ/body staining and imaging based on electrolyte-gel properties of biological tissues

Nature communications, 2020-04, Vol.11 (1), p.1982-22, Article 1982

2020

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Involvement of Ca2+-Dependent Hyperpolarization in Sleep Duration in Mammals

Neuron (Cambridge, Mass.), 2016-04, Vol.90 (1), p.70-85

2016

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CUBIC pathology: three-dimensional imaging for pathological diagnosis

Scientific reports, 2017-08, Vol.7 (1), p.9269-14, Article 9269

2017

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Visualization and molecular characterization of whole-brain vascular networks with capillary resolution

Nature communications, 2020-02, Vol.11 (1), p.1104-1104, Article 1104

2020

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Comprehensive three-dimensional analysis (CUBIC-kidney) visualizes abnormal renal sympathetic nerves after ischemia/reperfusion injury

Kidney international, 2019-07, Vol.96 (1), p.129-138

2019

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Knockout-Rescue Embryonic Stem Cell-Derived Mouse Reveals Circadian-Period Control by Quality and Quantity of CRY1

Molecular cell, 2017-01, Vol.65 (1), p.176-190

2017

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Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism

Nature communications, 2017-12, Vol.8 (1), p.1930-10, Article 1930

2017

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Perspective: Extending the Utility of Three-Dimensional Organoids by Tissue Clearing Technologies

Frontiers in cell and developmental biology, 2021-06, Vol.9, p.679226

2021

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Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation

Nature communications, 2024-07, Vol.15 (1), p.6054-19, Article 6054

2024

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Comparison of the 3-D patterns of the parasympathetic nervous system in the lung at late developmental stages between mouse and chicken

Developmental biology, 2018-12, Vol.444, p.S325-S336

2018

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Sleep as a biological problem: an overview of frontiers in sleep research

The journal of physiological sciences, 2016-01, Vol.66 (1), p.1-13

2016

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Signal improved ultra-fast light-sheet microscope for large tissue imaging

Communications engineering, 2024-04, Vol.3 (1), p.59-13, Article 59

2024

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CUBIC-Cloud provides an integrative computational framework toward community-driven whole-mouse-brain mapping

Cell reports methods, 2021-06, Vol.1 (2), p.100038, Article 100038

2021

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Recent Developments in a Automated Diagnosis of Pathological Images and Three-dimensional Histopathology

Brain and nerve = Shinkei kenkyū no shinpo, 2019-07, Vol.71 (7), p.723

Susaki, Etsuo A

2019

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Non-enzymatic DNA cleavage reaction induced by 5-ethynyluracil in methylamine aqueous solution and application to DNA concatenation

PloS one, 2014-03, Vol.9 (3), p.e92369-e92369

2014

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Realization of cellomics to dive into the whole-body or whole-organ cell cloud

Nature methods, 2024-07, Vol.21 (7), p.1138-1142

2024

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Next-generation mammalian genetics toward organism-level systems biology

NPJ systems biology and applications, 2017-01, Vol.3 (1), p.15-11, Article 15

2017

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Whole-body and Whole-Organ Clearing and Imaging Techniques with Single-Cell Resolution: Toward Organism-Level Systems Biology in Mammals

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

Whole-body imaging with single-cell resolution by tissue decolorization

Color-Changing Fluorescent Barcode Based on Strand Displacement Reaction Enables Simple Multiplexed Labeling

Lipopolysaccharides and Cellular Senescence: Involvement in Atherosclerosis

The oral hypoxia-inducible factor prolyl hydroxylase inhibitor enarodustat counteracts alterations in renal energy metabolism in the early stages of diabetic kidney disease

Versatile whole-organ/body staining and imaging based on electrolyte-gel properties of biological tissues

Involvement of Ca2+-Dependent Hyperpolarization in Sleep Duration in Mammals

CUBIC pathology: three-dimensional imaging for pathological diagnosis

Visualization and molecular characterization of whole-brain vascular networks with capillary resolution

Comprehensive three-dimensional analysis (CUBIC-kidney) visualizes abnormal renal sympathetic nerves after ischemia/reperfusion injury

Knockout-Rescue Embryonic Stem Cell-Derived Mouse Reveals Circadian-Period Control by Quality and Quantity of CRY1

Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism

Perspective: Extending the Utility of Three-Dimensional Organoids by Tissue Clearing Technologies

Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation

Comparison of the 3-D patterns of the parasympathetic nervous system in the lung at late developmental stages between mouse and chicken

Sleep as a biological problem: an overview of frontiers in sleep research

Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo

Signal improved ultra-fast light-sheet microscope for large tissue imaging

CUBIC-Cloud provides an integrative computational framework toward community-driven whole-mouse-brain mapping

Recent Developments in a Automated Diagnosis of Pathological Images and Three-dimensional Histopathology

Non-enzymatic DNA cleavage reaction induced by 5-ethynyluracil in methylamine aqueous solution and application to DNA concatenation

Realization of cellomics to dive into the whole-body or whole-organ cell cloud

Next-generation mammalian genetics toward organism-level systems biology

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